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The map label for this gene is hyi [H]

Identifier: 29143173

GI number: 29143173

Start: 2894357

End: 2895133

Strand: Reverse

Name: hyi [H]

Synonym: t2816

Alternate gene names: 29143173

Gene position: 2895133-2894357 (Counterclockwise)

Preceding gene: 29143174

Following gene: 29143172

Centisome position: 60.42

GC content: 57.53

Gene sequence:

>777_bases
ATGCCGCGTTTTGCCGCCGATTTGTCGATGATGTTTACCGAAGTGCCGTTTATCGAGCGTTTTGCCGCTGCTGCCGAAGC
CGGTTTTCAGGCCGTTGAGTTTCTGTTCCCCTACGGCTTTGCCGCCAGCGAGATTAAAGCCCAGCTATCGCGTCATGATC
TGACGCTGGCGCTGTTTAATACTTCGGCGGGTGATACCGCGGCGGGCGAGTGGGGACGTGCCGCGCTACCGGGGCGCGAA
CACGACGCGCGCGCCGATATTGATCTGGCTCTGGAATACGCTCTGGCGCTGGAATGCGAGCAGGTTCACATCATGGCGGG
CGTCGTGCCGGATGGCGCTGATGGCGCACGTTATCGCGCCACGTTTATCGATAATTTGCGTTATGCCGCCGGCCGGTTTG
CCGCCCACGATAAACGTATTTTGATCGAAGCGCTGAGTCCCGGCGTTAAACCCGGCTACCTCTTTTCCAGCCAATATCAG
GCGCTGGGCATCGCAGAAGAGGTTGACCGCCCAAATGTATTCATCCAGCTCGACACTTTCCACGCGCAAAAAGTGGATGG
CAATTTGAGTCACCTGATTCGCGAGTACGCGGGCCGCTATGCCCATGTACAAATCGCCTCGCTACCGGACAGACATGAAC
CGGATGATGGCGAGATCAACTACCCGTGGCTGTTCCGGCTGTTCGATGACGTAGGTTATTGCGGCTGGATAGGCTGCGAA
TACCAACCACGGAATACCACTCAGGAGGGGCTTGGCTGGTTTAACGCCTGGCGCTAA

Upstream 100 bases:

>100_bases
GAGGAGCTGGAAGAGACGGCAAAGCTGATTTTTATCCTTGGCGAACGCCCGATTCGTTATTTAACCACCGAAGAAATTGC
GCAGTTAAGGAGATAACCCG

Downstream 100 bases:

>100_bases
CCCTGAACTACCCTACACAACAATAAAGAGGACATCCGGATGCAGATTATCATTACCGGCGGGGGCGGCTTTTTAGGCCA
GAAACTCGCAAGCGCCTTAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MPRFAADLSMMFTEVPFIERFAAAAEAGFQAVEFLFPYGFAASEIKAQLSRHDLTLALFNTSAGDTAAGEWGRAALPGRE
HDARADIDLALEYALALECEQVHIMAGVVPDGADGARYRATFIDNLRYAAGRFAAHDKRILIEALSPGVKPGYLFSSQYQ
ALGIAEEVDRPNVFIQLDTFHAQKVDGNLSHLIREYAGRYAHVQIASLPDRHEPDDGEINYPWLFRLFDDVGYCGWIGCE
YQPRNTTQEGLGWFNAWR

Sequences:

>Translated_258_residues
MPRFAADLSMMFTEVPFIERFAAAAEAGFQAVEFLFPYGFAASEIKAQLSRHDLTLALFNTSAGDTAAGEWGRAALPGRE
HDARADIDLALEYALALECEQVHIMAGVVPDGADGARYRATFIDNLRYAAGRFAAHDKRILIEALSPGVKPGYLFSSQYQ
ALGIAEEVDRPNVFIQLDTFHAQKVDGNLSHLIREYAGRYAHVQIASLPDRHEPDDGEINYPWLFRLFDDVGYCGWIGCE
YQPRNTTQEGLGWFNAWR
>Mature_257_residues
PRFAADLSMMFTEVPFIERFAAAAEAGFQAVEFLFPYGFAASEIKAQLSRHDLTLALFNTSAGDTAAGEWGRAALPGREH
DARADIDLALEYALALECEQVHIMAGVVPDGADGARYRATFIDNLRYAAGRFAAHDKRILIEALSPGVKPGYLFSSQYQA
LGIAEEVDRPNVFIQLDTFHAQKVDGNLSHLIREYAGRYAHVQIASLPDRHEPDDGEINYPWLFRLFDDVGYCGWIGCEY
QPRNTTQEGLGWFNAWR

Specific function: Unknown

COG id: COG3622

COG function: function code G; Hydroxypyruvate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hyi family [H]

Homologues:

Organism=Homo sapiens, GI300068962, Length=262, Percent_Identity=42.7480916030534, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI300068964, Length=243, Percent_Identity=41.5637860082305, Blast_Score=180, Evalue=1e-45,
Organism=Escherichia coli, GI1789095, Length=258, Percent_Identity=79.8449612403101, Blast_Score=433, Evalue=1e-123,
Organism=Escherichia coli, GI1786718, Length=258, Percent_Identity=41.0852713178295, Blast_Score=216, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17552022, Length=240, Percent_Identity=34.1666666666667, Blast_Score=150, Evalue=7e-37,
Organism=Drosophila melanogaster, GI17530883, Length=258, Percent_Identity=35.2713178294574, Blast_Score=164, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: NA

Molecular weight: Translated: 28799; Mature: 28667

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRFAADLSMMFTEVPFIERFAAAAEAGFQAVEFLFPYGFAASEIKAQLSRHDLTLALFN
CCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEEEE
TSAGDTAAGEWGRAALPGREHDARADIDLALEYALALECEQVHIMAGVVPDGADGARYRA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEECCEEEEEEEECCCCCCCCEEEH
TFIDNLRYAAGRFAAHDKRILIEALSPGVKPGYLFSSQYQALGIAEEVDRPNVFIQLDTF
HHHHHHHHHHHHHHCCCCEEEEEHHCCCCCCCEEECCCCHHHCCHHHCCCCCEEEEEECC
HAQKVDGNLSHLIREYAGRYAHVQIASLPDRHEPDDGEINYPWLFRLFDDVGYCGWIGCE
CCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCEEEECCC
YQPRNTTQEGLGWFNAWR
CCCCCCCHHHCCHHHCCC
>Mature Secondary Structure 
PRFAADLSMMFTEVPFIERFAAAAEAGFQAVEFLFPYGFAASEIKAQLSRHDLTLALFN
CCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCEEEEEEE
TSAGDTAAGEWGRAALPGREHDARADIDLALEYALALECEQVHIMAGVVPDGADGARYRA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHEECCEEEEEEEECCCCCCCCEEEH
TFIDNLRYAAGRFAAHDKRILIEALSPGVKPGYLFSSQYQALGIAEEVDRPNVFIQLDTF
HHHHHHHHHHHHHHCCCCEEEEEHHCCCCCCCEEECCCCHHHCCHHHCCCCCEEEEEECC
HAQKVDGNLSHLIREYAGRYAHVQIASLPDRHEPDDGEINYPWLFRLFDDVGYCGWIGCE
CCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCEEEECCC
YQPRNTTQEGLGWFNAWR
CCCCCCCHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]