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The map label for this gene is spaR [H]

Identifier: 29143149

GI number: 29143149

Start: 2870447

End: 2871238

Strand: Reverse

Name: spaR [H]

Synonym: t2790

Alternate gene names: 29143149

Gene position: 2871238-2870447 (Counterclockwise)

Preceding gene: 29143150

Following gene: 29143148

Centisome position: 59.92

GC content: 49.75

Gene sequence:

>792_bases
ATGCTTTACGCGTTGTACTTTGAAATTCATCACCTGGTTGCGTCTGCGGCACTAGGGTTTGCTCGCGTAGCGCCGATTTT
TTTCTTCCTGCCGTTTTTGAATAGCGGGGTATTAAGCGGCGCGCCGAGAAACGCCATTATCATCCTGGTGGCATTGGGAG
TATGGCCGCATGCATTGAACGAGGCGCCGCCGTTTTTATCGGTGGCGATGATCCCGTTAGTTCTGCAAGAAGCGGCGGTA
GGCGTCATGCTGGGCTGTCTGCTGTCATGGCCTTTTTGGGTTATGCATGCGCTGGGTTGTATTATCGATAACCAGCGAGG
GGCAACGCTAAGTAGCAGTATCGATCCGGCAAACGGTATTGATACCTCGGAAATGGCTAATTTCCTGAATATGTTTGCCG
CTGTCGTTTATTTACAAAACGGCGGTCTGGTCACGATGGTTGACGTGTTAAATAAAAGCTATCAGCTATGCGATCCGATG
AACGAGTGCACGCCTTCATTACCGCCGCTATTAACGTTTATTAATCAGGTGGCTCAAAACGCCTTGGTTCTGGCCAGTCC
GGTGGTATTAGTGCTGTTGCTGTCAGAAGTATTCCTGGGTTTATTGTCGCGCTTTGCTCCGCAAATGAACGCTTTTGCGA
TTTCACTGACGGTAAAAAGCGGCATTGCCGTTTTAATTATGCTGCTTTATTTCTCTCCGGTACTACCGGACAATGTACCG
CGACTCTCTTTCCAGGCCACAGGGTTAAGCAGTTGGTTTTACGAGCGAGGGGCGACGCATGTCCTCGAATAA

Upstream 100 bases:

>100_bases
CGTGTGTTTATGCTTGTTTTTACTGTCTGGCTGGTATGGCGAAGTTTTACTCTCTTACGGGCGTCAGGTGATATTCCTGG
CGTTGGCTAAGGGGTAAAAA

Downstream 100 bases:

>100_bases
AACAGAAAAACCGACTAAAAAACGGCTGGAAGACTCCGCTAAAAAAGGCCAGTCATTTAAAAGTAAAGATCTCATTATCG
CCTGTCTGACGCTGGGAGGA

Product: virulence-associated secretory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MLYALYFEIHHLVASAALGFARVAPIFFFLPFLNSGVLSGAPRNAIIILVALGVWPHALNEAPPFLSVAMIPLVLQEAAV
GVMLGCLLSWPFWVMHALGCIIDNQRGATLSSSIDPANGIDTSEMANFLNMFAAVVYLQNGGLVTMVDVLNKSYQLCDPM
NECTPSLPPLLTFINQVAQNALVLASPVVLVLLLSEVFLGLLSRFAPQMNAFAISLTVKSGIAVLIMLLYFSPVLPDNVP
RLSFQATGLSSWFYERGATHVLE

Sequences:

>Translated_263_residues
MLYALYFEIHHLVASAALGFARVAPIFFFLPFLNSGVLSGAPRNAIIILVALGVWPHALNEAPPFLSVAMIPLVLQEAAV
GVMLGCLLSWPFWVMHALGCIIDNQRGATLSSSIDPANGIDTSEMANFLNMFAAVVYLQNGGLVTMVDVLNKSYQLCDPM
NECTPSLPPLLTFINQVAQNALVLASPVVLVLLLSEVFLGLLSRFAPQMNAFAISLTVKSGIAVLIMLLYFSPVLPDNVP
RLSFQATGLSSWFYERGATHVLE
>Mature_263_residues
MLYALYFEIHHLVASAALGFARVAPIFFFLPFLNSGVLSGAPRNAIIILVALGVWPHALNEAPPFLSVAMIPLVLQEAAV
GVMLGCLLSWPFWVMHALGCIIDNQRGATLSSSIDPANGIDTSEMANFLNMFAAVVYLQNGGLVTMVDVLNKSYQLCDPM
NECTPSLPPLLTFINQVAQNALVLASPVVLVLLLSEVFLGLLSRFAPQMNAFAISLTVKSGIAVLIMLLYFSPVLPDNVP
RLSFQATGLSSWFYERGATHVLE

Specific function: Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells [H]

COG id: COG4791

COG function: function code U; Type III secretory pathway, component EscT

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliR/mopE/spaR family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002010
- InterPro:   IPR006304 [H]

Pfam domain/function: PF01311 Bac_export_1 [H]

EC number: NA

Molecular weight: Translated: 28437; Mature: 28437

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYALYFEIHHLVASAALGFARVAPIFFFLPFLNSGVLSGAPRNAIIILVALGVWPHALN
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHCCHHHHC
EAPPFLSVAMIPLVLQEAAVGVMLGCLLSWPFWVMHALGCIIDNQRGATLSSSIDPANGI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
DTSEMANFLNMFAAVVYLQNGGLVTMVDVLNKSYQLCDPMNECTPSLPPLLTFINQVAQN
CHHHHHHHHHHHHHHHHHCCCCEEHHHHHHCCHHHHCCCHHHCCCCCCHHHHHHHHHHHH
ALVLASPVVLVLLLSEVFLGLLSRFAPQMNAFAISLTVKSGIAVLIMLLYFSPVLPDNVP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCC
RLSFQATGLSSWFYERGATHVLE
CCEEECCCHHHHHHHCCCHHCCC
>Mature Secondary Structure
MLYALYFEIHHLVASAALGFARVAPIFFFLPFLNSGVLSGAPRNAIIILVALGVWPHALN
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEHHCCHHHHC
EAPPFLSVAMIPLVLQEAAVGVMLGCLLSWPFWVMHALGCIIDNQRGATLSSSIDPANGI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
DTSEMANFLNMFAAVVYLQNGGLVTMVDVLNKSYQLCDPMNECTPSLPPLLTFINQVAQN
CHHHHHHHHHHHHHHHHHCCCCEEHHHHHHCCHHHHCCCHHHCCCCCCHHHHHHHHHHHH
ALVLASPVVLVLLLSEVFLGLLSRFAPQMNAFAISLTVKSGIAVLIMLLYFSPVLPDNVP
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCC
RLSFQATGLSSWFYERGATHVLE
CCEEECCCHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8404849; 11677609 [H]