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The map label for this gene is hypD [H]

Identifier: 29143118

GI number: 29143118

Start: 2840106

End: 2841227

Strand: Direct

Name: hypD [H]

Synonym: t2759

Alternate gene names: 29143118

Gene position: 2840106-2841227 (Clockwise)

Preceding gene: 29143117

Following gene: 29143119

Centisome position: 59.27

GC content: 58.2

Gene sequence:

>1122_bases
ATGCGTTTTGTTGACGAGTACCGTGCGCCGGAACAGGTAATGCAGCTCATTGAACACCTGCGTGAACGCGCCGCCCTTCT
TCCTTACACTGCTGAACGACCGCTGCGCATTATGGAAGTCTGCGGGGGTCATACCCACGCGATTTTTAAATTTGGTCTCG
ATCAGTTACTGCCCGAAAACGTGGAGTTTATTCACGGCCCCGGTTGTCCGGTCTGCGTGCTGCCAATGGGACGCATCGAC
AGTTGCGTGGAAATCGCCAGCCATCCGGAGGTGATTTTCTGCACCTTTGGCGATGCCATGCGCGTGCCGGGGAAACAGGG
TTCTCTGTTGCAGGCTAAAGCGCGCGGCGCGGATGTGCGTATTGTTTATTCTCCGATGGACGCGCTGAAGCTGGCGCAGG
ATAACCCGACCCGCAAAGTGGTATTTTTCGGGCTGGGCTTTGAAACCACCATGCCGACCACCGCCATCACGCTACAGCAG
GCAAAACAGCGTGACGTGCGAAACTTCTACTTTTTCTGCCAGCACATTACACTGATCCCGACGCTGCGTAGCCTACTGGA
GCAGCCGGACAACGGCATTGACGCCTTTCTTGCGCCAGGCCACGTCAGCATGGTCATCGGCACCGAGGCGTACCAGTTTA
TCGCCGCCGATTTTCATCGCCCGCTGGTGGTGGCTGGATTCGAACCGCTTGATCTACTGCAAGGCGTGGTCATGCTGGTT
GAGCAGAAAATAGCGGCCCTAAGCCAGGTTGAAAACCAATACCGTCGCGTGGTGCCGGATGCCGGAAACATGCTGGCGCA
GCAGGCCATCGCCGATGTGTTCTGCGTTAATGGCGACAGCGAGTGGCGCGGCCTGGGCGTGATTGAATCCTCCGGCGTCC
ACCTGACGCCGGAGTATCAGCGCTTTGACGCCGAAGCGCATTTCCGCCCAGCGCCACAGCAGGTCTATGACGATCCGCGC
GCCCGCTGCGGCGAAGTGCTGACCGGCAGATGCAAGCCGCATCAGTGCCCGCTATTTGGTAAAACATGTAATCCAGAGAC
CGCGTTCGGCGCGCTGATGGTCTCTTCCGAAGGCGCATGCGCCGCCTGGTATCAGTATCGTCAGCAGGAGTGTGAAGTTT
GA

Upstream 100 bases:

>100_bases
TCATTAACGAAGCGGAAGCGCGCGACACGCTCGACGCGCTACAAAATATGTTTGATGTTGAGCCGGACGTCGGCGCACTG
CTGTATGGTGAGGAGAGATA

Downstream 100 bases:

>100_bases
ACAATATACAACTCGCCCACGGCAGCGGCGGCCAGGCTATGCAACAGTTGATTAATAGCCTGTTTATGGAGGCCTTTGCC
AACCCGTGGCTGGCGGAACA

Product: hydrogenase isoenzyme formation protein HypD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MRFVDEYRAPEQVMQLIEHLRERAALLPYTAERPLRIMEVCGGHTHAIFKFGLDQLLPENVEFIHGPGCPVCVLPMGRID
SCVEIASHPEVIFCTFGDAMRVPGKQGSLLQAKARGADVRIVYSPMDALKLAQDNPTRKVVFFGLGFETTMPTTAITLQQ
AKQRDVRNFYFFCQHITLIPTLRSLLEQPDNGIDAFLAPGHVSMVIGTEAYQFIAADFHRPLVVAGFEPLDLLQGVVMLV
EQKIAALSQVENQYRRVVPDAGNMLAQQAIADVFCVNGDSEWRGLGVIESSGVHLTPEYQRFDAEAHFRPAPQQVYDDPR
ARCGEVLTGRCKPHQCPLFGKTCNPETAFGALMVSSEGACAAWYQYRQQECEV

Sequences:

>Translated_373_residues
MRFVDEYRAPEQVMQLIEHLRERAALLPYTAERPLRIMEVCGGHTHAIFKFGLDQLLPENVEFIHGPGCPVCVLPMGRID
SCVEIASHPEVIFCTFGDAMRVPGKQGSLLQAKARGADVRIVYSPMDALKLAQDNPTRKVVFFGLGFETTMPTTAITLQQ
AKQRDVRNFYFFCQHITLIPTLRSLLEQPDNGIDAFLAPGHVSMVIGTEAYQFIAADFHRPLVVAGFEPLDLLQGVVMLV
EQKIAALSQVENQYRRVVPDAGNMLAQQAIADVFCVNGDSEWRGLGVIESSGVHLTPEYQRFDAEAHFRPAPQQVYDDPR
ARCGEVLTGRCKPHQCPLFGKTCNPETAFGALMVSSEGACAAWYQYRQQECEV
>Mature_373_residues
MRFVDEYRAPEQVMQLIEHLRERAALLPYTAERPLRIMEVCGGHTHAIFKFGLDQLLPENVEFIHGPGCPVCVLPMGRID
SCVEIASHPEVIFCTFGDAMRVPGKQGSLLQAKARGADVRIVYSPMDALKLAQDNPTRKVVFFGLGFETTMPTTAITLQQ
AKQRDVRNFYFFCQHITLIPTLRSLLEQPDNGIDAFLAPGHVSMVIGTEAYQFIAADFHRPLVVAGFEPLDLLQGVVMLV
EQKIAALSQVENQYRRVVPDAGNMLAQQAIADVFCVNGDSEWRGLGVIESSGVHLTPEYQRFDAEAHFRPAPQQVYDDPR
ARCGEVLTGRCKPHQCPLFGKTCNPETAFGALMVSSEGACAAWYQYRQQECEV

Specific function: Required for the formation of all three hydrogenase isoenzymes [H]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=372, Percent_Identity=94.6236559139785, Blast_Score=736, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 41559; Mature: 41559

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFVDEYRAPEQVMQLIEHLRERAALLPYTAERPLRIMEVCGGHTHAIFKFGLDQLLPEN
CCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHCHHHHCCCC
VEFIHGPGCPVCVLPMGRIDSCVEIASHPEVIFCTFGDAMRVPGKQGSLLQAKARGADVR
CCEEECCCCCEEEEECCCHHHHHHHHCCCCEEEEECCCHHCCCCCCCCEEEHHCCCCCEE
IVYSPMDALKLAQDNPTRKVVFFGLGFETTMPTTAITLQQAKQRDVRNFYFFCQHITLIP
EEECCHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLRSLLEQPDNGIDAFLAPGHVSMVIGTEAYQFIAADFHRPLVVAGFEPLDLLQGVVMLV
HHHHHHHCCCCCCCEEECCCEEEEEECCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHH
EQKIAALSQVENQYRRVVPDAGNMLAQQAIADVFCVNGDSEWRGLGVIESSGVHLTPEYQ
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEECCCCCCCEEEEEECCCCEECCHHH
RFDAEAHFRPAPQQVYDDPRARCGEVLTGRCKPHQCPLFGKTCNPETAFGALMVSSEGAC
HCCCCCCCCCCCHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHEEEEEECCCCH
AAWYQYRQQECEV
HHHHHHHHHHCCC
>Mature Secondary Structure
MRFVDEYRAPEQVMQLIEHLRERAALLPYTAERPLRIMEVCGGHTHAIFKFGLDQLLPEN
CCCHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHHHHCHHHHCCCC
VEFIHGPGCPVCVLPMGRIDSCVEIASHPEVIFCTFGDAMRVPGKQGSLLQAKARGADVR
CCEEECCCCCEEEEECCCHHHHHHHHCCCCEEEEECCCHHCCCCCCCCEEEHHCCCCCEE
IVYSPMDALKLAQDNPTRKVVFFGLGFETTMPTTAITLQQAKQRDVRNFYFFCQHITLIP
EEECCHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLRSLLEQPDNGIDAFLAPGHVSMVIGTEAYQFIAADFHRPLVVAGFEPLDLLQGVVMLV
HHHHHHHCCCCCCCEEECCCEEEEEECCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHH
EQKIAALSQVENQYRRVVPDAGNMLAQQAIADVFCVNGDSEWRGLGVIESSGVHLTPEYQ
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEEEECCCCCCCEEEEEECCCCEECCHHH
RFDAEAHFRPAPQQVYDDPRARCGEVLTGRCKPHQCPLFGKTCNPETAFGALMVSSEGAC
HCCCCCCCCCCCHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHEEEEEECCCCH
AAWYQYRQQECEV
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]