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The map label for this gene is hycA [H]

Identifier: 29143114

GI number: 29143114

Start: 2837874

End: 2838335

Strand: Reverse

Name: hycA [H]

Synonym: t2755

Alternate gene names: 29143114

Gene position: 2838335-2837874 (Counterclockwise)

Preceding gene: 29143121

Following gene: 29143113

Centisome position: 59.23

GC content: 51.08

Gene sequence:

>462_bases
ATGACTATTTGGGAAATAAGCGAAAAGGCCGATTACATCGCGCAACGGCATCGTCGCCTACAGGACCAGTGGCATATTTA
CTGCAACTCGCTGGTTCAGGGGATCACCCTCTCGAAAGCGCGCCTGCATCACGCAATGAGCTGCGCGCCGGAAAGGGATC
TTTGCTTTGTCCTGTTTGAGCACTTTCGTATTTACGTTGCGTTGGCGGATGGTTTTAACAGCCACACCATTGAGTACTAC
GTTGAAACCAAAGATGGCGAAGATAAGCAATTGATTGCACAGGCGCAGCTCGATATCGACGGCAAGGTTGACGAACGGGT
TAACAACCGCGATCGCGAGCAGGTGCTGGAGCACTATCTGGAAAAAATCGCCAGCGTTTACGACAGCCTCTATACCGCTG
TAGAAACCAACTCGCCGGTTAATTTGCGCCAATTGGTAAAGGGACACAGCCCGGCTGTATAA

Upstream 100 bases:

>100_bases
AACGGCAGTAACTGTGCGCGTCTTCCATTAAAAACAATAAGTTAAAAATTGGCATGGAAAATGCTTAACGCAGGCATCTC
TGTTAAACGGGTAACCTGAC

Downstream 100 bases:

>100_bases
GCCTGAGGCGTTGCCCGCTTTGATTCGCGATGTGGCGTTGCGCCATGTCATGAATGTTTTGGGGATGGGCGTGTCGATAA
GTGTCGAAAATGACATTTCA

Product: formate hydrogenlyase regulatory protein HycA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MTIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKARLHHAMSCAPERDLCFVLFEHFRIYVALADGFNSHTIEYY
VETKDGEDKQLIAQAQLDIDGKVDERVNNRDREQVLEHYLEKIASVYDSLYTAVETNSPVNLRQLVKGHSPAV

Sequences:

>Translated_153_residues
MTIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKARLHHAMSCAPERDLCFVLFEHFRIYVALADGFNSHTIEYY
VETKDGEDKQLIAQAQLDIDGKVDERVNNRDREQVLEHYLEKIASVYDSLYTAVETNSPVNLRQLVKGHSPAV
>Mature_152_residues
TIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKARLHHAMSCAPERDLCFVLFEHFRIYVALADGFNSHTIEYYV
ETKDGEDKQLIAQAQLDIDGKVDERVNNRDREQVLEHYLEKIASVYDSLYTAVETNSPVNLRQLVKGHSPAV

Specific function: Regulatory protein for the formate hydrogenlyase system. Could act by directly interacting with fhlA or by preventing the binding of fhlA to the upstream activatory sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789080, Length=152, Percent_Identity=88.8157894736842, Blast_Score=287, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021285 [H]

Pfam domain/function: PF11046 HycA_repressor [H]

EC number: NA

Molecular weight: Translated: 17791; Mature: 17660

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKARLHHAMSCAPERDLCFVLFE
CCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
HFRIYVALADGFNSHTIEYYVETKDGEDKQLIAQAQLDIDGKVDERVNNRDREQVLEHYL
HHHEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHH
EKIASVYDSLYTAVETNSPVNLRQLVKGHSPAV
HHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure 
TIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKARLHHAMSCAPERDLCFVLFE
CEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
HFRIYVALADGFNSHTIEYYVETKDGEDKQLIAQAQLDIDGKVDERVNNRDREQVLEHYL
HHHEEEEEECCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHH
EKIASVYDSLYTAVETNSPVNLRQLVKGHSPAV
HHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]