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The map label for this gene is allR [H]

Identifier: 29142735

GI number: 29142735

Start: 2410496

End: 2411314

Strand: Reverse

Name: allR [H]

Synonym: t2344

Alternate gene names: 29142735

Gene position: 2411314-2410496 (Counterclockwise)

Preceding gene: 29142738

Following gene: 29142734

Centisome position: 50.32

GC content: 54.46

Gene sequence:

>819_bases
ATGACGGAAGTAAGACGACGCGGCAGGCCAGGACAGGCAGAGCCGACTGCGCAGAAAGGCGCTCAGGCGCTGGAGAGGGG
CATAGCGATATTGCAATATCTCGAAAGAAGCGGCGGCAGTTCATCAGTTAGCGATATTTCCGGCAGCCTGGATTTACCGC
TTTCTACGACGTTTCGCCTGTTAAAGGTACTGCAAGCGGCTGATTTTGTGTACCAGGATAGCCAGCTTGGCTGGTGGCAT
ATTGGTTTAGGCGTATTTAATGTGGGCTCTGCGTATATTCATAATCGCGATGTCCTCTCGGTGGCCGGGCCCTTTATGCA
CCGACTTATGCTGCTTTCTGGCGAGACGGTCAACGTAGCGATTCGCAACGGTAATGAAGCGGTGTTAATCGGTCAAAAGG
AGTGCAAATCGATGGTCAGAATGTGCGCGCCCTTAGGGAGTCGTCTGCCGTTACATGCTTCCGGCGCCGGAAAAGCGCTG
CTTTACCCGCTCACCGAAGAAGAGCTGGTGGGGATCGTTGTCAATACTGGTTTGCGGCGGTTTACGCCGACCACTTTGGT
GGATTTACCTATCCTGCTTAAAAATCTGGAGCGGGCGCGTGAACAGGGCTATACCGTTGACCAGGAAGAACATGTTGTCG
GGCTGAATTGTATCGCCTCCGCTATCTATGACGATGCGGGCAGCGTGGTCGCCGCTATCTCAATATCGGGACCGGCTTCC
CGGCTGACGGAAGATCGCTTTATCAGCCAGGGTGAACTGGTACGGGATACCGCGAAAGACATCAGTACGGCGCTTGGGCT
AAAACCCCCTGTAGCCTGA

Upstream 100 bases:

>100_bases
ACATGAACTCTGTTTTGCGTGACGCTATTGGCCTTCTTGCATAAGATGAACATATTGTTCATTGTTTATGCTCATATTTT
GGGCCGGAGTTAACGTAAAT

Downstream 100 bases:

>100_bases
GCCGCATCCCGCTCGCTGGAGCGGGACTTTTTTAAAATTTTTAAAAGTTGGAAACTTTTTCCAATAAAAAGAGGTAGCAA
TAAAATGGCAAAAATGAGAG

Product: DNA-binding transcriptional repressor AllR

Products: NA

Alternate protein names: Negative regulator of allantoin and glyoxylate utilization operons [H]

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MTEVRRRGRPGQAEPTAQKGAQALERGIAILQYLERSGGSSSVSDISGSLDLPLSTTFRLLKVLQAADFVYQDSQLGWWH
IGLGVFNVGSAYIHNRDVLSVAGPFMHRLMLLSGETVNVAIRNGNEAVLIGQKECKSMVRMCAPLGSRLPLHASGAGKAL
LYPLTEEELVGIVVNTGLRRFTPTTLVDLPILLKNLERAREQGYTVDQEEHVVGLNCIASAIYDDAGSVVAAISISGPAS
RLTEDRFISQGELVRDTAKDISTALGLKPPVA

Sequences:

>Translated_272_residues
MTEVRRRGRPGQAEPTAQKGAQALERGIAILQYLERSGGSSSVSDISGSLDLPLSTTFRLLKVLQAADFVYQDSQLGWWH
IGLGVFNVGSAYIHNRDVLSVAGPFMHRLMLLSGETVNVAIRNGNEAVLIGQKECKSMVRMCAPLGSRLPLHASGAGKAL
LYPLTEEELVGIVVNTGLRRFTPTTLVDLPILLKNLERAREQGYTVDQEEHVVGLNCIASAIYDDAGSVVAAISISGPAS
RLTEDRFISQGELVRDTAKDISTALGLKPPVA
>Mature_271_residues
TEVRRRGRPGQAEPTAQKGAQALERGIAILQYLERSGGSSSVSDISGSLDLPLSTTFRLLKVLQAADFVYQDSQLGWWHI
GLGVFNVGSAYIHNRDVLSVAGPFMHRLMLLSGETVNVAIRNGNEAVLIGQKECKSMVRMCAPLGSRLPLHASGAGKALL
YPLTEEELVGIVVNTGLRRFTPTTLVDLPILLKNLERAREQGYTVDQEEHVVGLNCIASAIYDDAGSVVAAISISGPASR
LTEDRFISQGELVRDTAKDISTALGLKPPVA

Specific function: Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786715, Length=268, Percent_Identity=90.6716417910448, Blast_Score=501, Evalue=1e-143,
Organism=Escherichia coli, GI87082359, Length=264, Percent_Identity=42.0454545454545, Blast_Score=216, Evalue=9e-58,
Organism=Escherichia coli, GI1786468, Length=245, Percent_Identity=30.6122448979592, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1788131, Length=241, Percent_Identity=30.2904564315353, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1789999, Length=252, Percent_Identity=28.968253968254, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790752, Length=252, Percent_Identity=26.984126984127, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1788581, Length=249, Percent_Identity=28.1124497991968, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29248; Mature: 29117

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEVRRRGRPGQAEPTAQKGAQALERGIAILQYLERSGGSSSVSDISGSLDLPLSTTFRL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHH
LKVLQAADFVYQDSQLGWWHIGLGVFNVGSAYIHNRDVLSVAGPFMHRLMLLSGETVNVA
HHHHHHHHHHEECCCCCEEEECCHHHHCCCHHEECCCHHHHHHHHHHHHHHHCCCEEEEE
IRNGNEAVLIGQKECKSMVRMCAPLGSRLPLHASGAGKALLYPLTEEELVGIVVNTGLRR
EECCCEEEEEEHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEECCHHHHEEHHHHCCCHH
FTPTTLVDLPILLKNLERAREQGYTVDQEEHVVGLNCIASAIYDDAGSVVAAISISGPAS
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHCCCCCEEEEEEECCCHH
RLTEDRFISQGELVRDTAKDISTALGLKPPVA
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TEVRRRGRPGQAEPTAQKGAQALERGIAILQYLERSGGSSSVSDISGSLDLPLSTTFRL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHH
LKVLQAADFVYQDSQLGWWHIGLGVFNVGSAYIHNRDVLSVAGPFMHRLMLLSGETVNVA
HHHHHHHHHHEECCCCCEEEECCHHHHCCCHHEECCCHHHHHHHHHHHHHHHCCCEEEEE
IRNGNEAVLIGQKECKSMVRMCAPLGSRLPLHASGAGKALLYPLTEEELVGIVVNTGLRR
EECCCEEEEEEHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEECCHHHHEEHHHHCCCHH
FTPTTLVDLPILLKNLERAREQGYTVDQEEHVVGLNCIASAIYDDAGSVVAAISISGPAS
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHCCCCCEEEEEEECCCHH
RLTEDRFISQGELVRDTAKDISTALGLKPPVA
HHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA