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The map label for this gene is dcuC [H]

Identifier: 29142640

GI number: 29142640

Start: 2304531

End: 2305916

Strand: Direct

Name: dcuC [H]

Synonym: t2240

Alternate gene names: 29142640

Gene position: 2304531-2305916 (Clockwise)

Preceding gene: 29142637

Following gene: 29142643

Centisome position: 48.09

GC content: 53.9

Gene sequence:

>1386_bases
ATGCTAACAGTTATAGAGCTCCTTATCGGAGTCGTCGTTATTGTGGGTGTAGCACGCTACATCATTAAGGGATATTCCGC
CACTGGCGTTTTATTTGTCGGCGGTCTGGTTCTGCTTATTATCAGCGCGCTGATGGGGCATAAGGTATTACCTGCCAGCG
AAACCAGTACCGGCTATACCGCAACAGATATTGTTGAATACATCAAAATTTTGCTTATGAGTCGCGGCGGCGATCTTGGC
ATGATGATCATGATGCTGTGCGGCTTTGCCGCCTATATGACGCATATCGGCGCAAATGATATGGTCGTGAAGCTGGCGTC
GAAACCTTTACAGTATATAAACTCGCCCTACCTGTTGATGATTGCCGCCTATTTTGTCGCCTGCCTGATGTCGCTGGCCG
TCTCTTCCGCGACGGGGCTTGGCGTACTGCTCATGGCTACTCTCTTCCCGGTGATGGTCAACGTCGGCATTAGCCGCGGC
GCGGCGGCGGCTATTTGCGCTTCGCCGGCCGCCATCATCCTCTCGCCAACGTCTGGCGATGTGGTTTTAGCCGCAAAAGC
GGCGGAGATGCCGTTAATCGATTTCGCGTTCAAAACCACGCTGCCGATTTCCATCGCCGCCATTATCGGTATGGCGATTG
CGCATTTTTTCTGGCAACGCTATCTGGATAAAAAAGAGAACATTTCACATGAGATGCTGGACGTGGCGGAGATTACCACC
ACGGCCCCGGCGTTTTATGCCCTTTTGCCGTTCACGCCCATTATCGGCGTACTGATTTTTGACGGTAAATGGGGGCCGCA
GTTGCACATTATTACCATTCTGGTCATCTGTATGCTGCTGGCCGCCGTGCTGGAATTCGTGCGCGGCTTCAACACGCAAA
ATGTGTTTTCCGGCCTGGAAGTGGCTTATCGCGGCATGGCGGATGCGTTTGCCGGCGTTGTGATGCTGCTGGTCGCGGCG
GGCGTTTTCGCCCAGGGGCTGAGCACCATTGGCTTTATCCAAAGTCTGATCTCGATTGCCACTTCTTTTGGGTCCGCCAG
CATTATTCTGATGCTGGTCTTAGTGATTTTAACCATGCTGGCCGCGATGACCACCGGTTCAGGCAATGCGCCTTTTTACG
CCTTTGTTGAGATGATCCCTAAACTGGCGCACTCCTCCGGTATCAACCCAGCCTATTTATCCATCCCAATGCTGCAAGCC
TCAAACCTGGGGCGCACGATTTCGCCGGTCTCCGGCGTCGTGGTCGCTGTCGCCGGGATGGCTAAAATATCACCGTTTGA
AGTGGTGAAGCGCACGTCCGTTCCGGTCATCGTCGGTCTGTTGATCGTCATTATCGCTACGGAAATTATGGTGCCAGGCG
CCTCTTCCGCCGTCACCGGCGGCTGA

Upstream 100 bases:

>100_bases
TGATTTTAATCAGTAAGGCGCCATCCTTTATTCGGTACATTTTTATACCACTTTTGTGGTTCTTATTTTTACTCTGGGTG
TCGATAAGACAGGGGAAACA

Downstream 100 bases:

>100_bases
TAGCCGGTAAGCCGGGGCGAGGGAAAACATCGCTCCGGCATCTTAAAGCGGGCTTAGCCGCCGTGATAAATACGCTGCGG
CCTGCCCACTTTGCCATGAA

Product: C4-dicarboxylate transporter DcuC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MLTVIELLIGVVVIVGVARYIIKGYSATGVLFVGGLVLLIISALMGHKVLPASETSTGYTATDIVEYIKILLMSRGGDLG
MMIMMLCGFAAYMTHIGANDMVVKLASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRG
AAAAICASPAAIILSPTSGDVVLAAKAAEMPLIDFAFKTTLPISIAAIIGMAIAHFFWQRYLDKKENISHEMLDVAEITT
TAPAFYALLPFTPIIGVLIFDGKWGPQLHIITILVICMLLAAVLEFVRGFNTQNVFSGLEVAYRGMADAFAGVVMLLVAA
GVFAQGLSTIGFIQSLISIATSFGSASIILMLVLVILTMLAAMTTGSGNAPFYAFVEMIPKLAHSSGINPAYLSIPMLQA
SNLGRTISPVSGVVVAVAGMAKISPFEVVKRTSVPVIVGLLIVIIATEIMVPGASSAVTGG

Sequences:

>Translated_461_residues
MLTVIELLIGVVVIVGVARYIIKGYSATGVLFVGGLVLLIISALMGHKVLPASETSTGYTATDIVEYIKILLMSRGGDLG
MMIMMLCGFAAYMTHIGANDMVVKLASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRG
AAAAICASPAAIILSPTSGDVVLAAKAAEMPLIDFAFKTTLPISIAAIIGMAIAHFFWQRYLDKKENISHEMLDVAEITT
TAPAFYALLPFTPIIGVLIFDGKWGPQLHIITILVICMLLAAVLEFVRGFNTQNVFSGLEVAYRGMADAFAGVVMLLVAA
GVFAQGLSTIGFIQSLISIATSFGSASIILMLVLVILTMLAAMTTGSGNAPFYAFVEMIPKLAHSSGINPAYLSIPMLQA
SNLGRTISPVSGVVVAVAGMAKISPFEVVKRTSVPVIVGLLIVIIATEIMVPGASSAVTGG
>Mature_461_residues
MLTVIELLIGVVVIVGVARYIIKGYSATGVLFVGGLVLLIISALMGHKVLPASETSTGYTATDIVEYIKILLMSRGGDLG
MMIMMLCGFAAYMTHIGANDMVVKLASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRG
AAAAICASPAAIILSPTSGDVVLAAKAAEMPLIDFAFKTTLPISIAAIIGMAIAHFFWQRYLDKKENISHEMLDVAEITT
TAPAFYALLPFTPIIGVLIFDGKWGPQLHIITILVICMLLAAVLEFVRGFNTQNVFSGLEVAYRGMADAFAGVVMLLVAA
GVFAQGLSTIGFIQSLISIATSFGSASIILMLVLVILTMLAAMTTGSGNAPFYAFVEMIPKLAHSSGINPAYLSIPMLQA
SNLGRTISPVSGVVVAVAGMAKISPFEVVKRTSVPVIVGLLIVIIATEIMVPGASSAVTGG

Specific function: Responsible for the transport of C4-dicarboxylates during anaerobic growth [H]

COG id: COG3069

COG function: function code C; C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuC/dcuD transporter (TC 2.A.61) family [H]

Homologues:

Organism=Escherichia coli, GI1786839, Length=460, Percent_Identity=93.0434782608696, Blast_Score=721, Evalue=0.0,
Organism=Escherichia coli, GI1789622, Length=447, Percent_Identity=35.7941834451902, Blast_Score=277, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018385
- InterPro:   IPR004669 [H]

Pfam domain/function: PF03606 DcuC [H]

EC number: NA

Molecular weight: Translated: 48197; Mature: 48197

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTVIELLIGVVVIVGVARYIIKGYSATGVLFVGGLVLLIISALMGHKVLPASETSTGYT
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ATDIVEYIKILLMSRGGDLGMMIMMLCGFAAYMTHIGANDMVVKLASKPLQYINSPYLLM
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHH
IAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRGAAAAICASPAAIILSPTSGD
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEECCCCC
VVLAAKAAEMPLIDFAFKTTLPISIAAIIGMAIAHFFWQRYLDKKENISHEMLDVAEITT
EEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHH
TAPAFYALLPFTPIIGVLIFDGKWGPQLHIITILVICMLLAAVLEFVRGFNTQNVFSGLE
HHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VAYRGMADAFAGVVMLLVAAGVFAQGLSTIGFIQSLISIATSFGSASIILMLVLVILTML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AAMTTGSGNAPFYAFVEMIPKLAHSSGINPAYLSIPMLQASNLGRTISPVSGVVVAVAGM
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHEEEEHHHHCCCCCCCCHHHHHHHHHHHH
AKISPFEVVKRTSVPVIVGLLIVIIATEIMVPGASSAVTGG
HHCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLTVIELLIGVVVIVGVARYIIKGYSATGVLFVGGLVLLIISALMGHKVLPASETSTGYT
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ATDIVEYIKILLMSRGGDLGMMIMMLCGFAAYMTHIGANDMVVKLASKPLQYINSPYLLM
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHH
IAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRGAAAAICASPAAIILSPTSGD
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEECCCCC
VVLAAKAAEMPLIDFAFKTTLPISIAAIIGMAIAHFFWQRYLDKKENISHEMLDVAEITT
EEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHCCHHHHHHHHHHHH
TAPAFYALLPFTPIIGVLIFDGKWGPQLHIITILVICMLLAAVLEFVRGFNTQNVFSGLE
HHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VAYRGMADAFAGVVMLLVAAGVFAQGLSTIGFIQSLISIATSFGSASIILMLVLVILTML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AAMTTGSGNAPFYAFVEMIPKLAHSSGINPAYLSIPMLQASNLGRTISPVSGVVVAVAGM
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHEEEEHHHHCCCCCCCCHHHHHHHHHHHH
AKISPFEVVKRTSVPVIVGLLIVIIATEIMVPGASSAVTGG
HHCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]