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The map label for this gene is citC [H]

Identifier: 29142643

GI number: 29142643

Start: 2308715

End: 2309740

Strand: Direct

Name: citC [H]

Synonym: t2243

Alternate gene names: 29142643

Gene position: 2308715-2309740 (Clockwise)

Preceding gene: 29142640

Following gene: 29142644

Centisome position: 48.18

GC content: 52.63

Gene sequence:

>1026_bases
ATGGCGGAGATCGCTCACTTTCTCAAAGAGAATGATTTAAGCGTCGATACCACTGTAGAAGTGTTTATTACCGTCAGCCG
TGATGACCGTCTTATTGCCTGCGGCGGTATTGCCGGAAATATCATTAAATGCGTGGCCATTAGCGAATCAGTACGCGGTG
AAGGCTTAGCGTTAACGCTGGCGACGGAATTGATTAATCTCGCCTGGGAACGGCACTGCACCCATCTTTTTATTTATACC
AAAACGGAATACGAAGCGCTGTTTAAACAGTGCAGCTTTTCGACGATAGCCAGCGTCCCTGGCGTGATGGTCTTAATGGA
AAATAGCGCGACCCGGTTGAAACGGTATGCGGAATCGCTGGCGACATTGCGTCACGAGGGAAAGAAAATTGGCTGTATTG
TGATGAACGCCAATCCTTTCACGCACGGCCATCGCTATCTGATCCAACAGGCGGCGGCACAGTGCGACTGGCTGCATCTG
TTCCTGGTCAAAGAAGATACGTCACGCTTTCCCTATGAAGACCGACTCGATCTGGTCCTTAAAGGGACTACCGATATCCC
GCGCTTAACCGTTCATCGCGGCTCCGAATACATTATTTCTCGTGCGACGTTCCCCTGCTATTTCATTAAAGAGCAGAGCG
TCATTAATCACTGTTATACCGAAATCGACCTGAAGATTTTCCGCCAGTATCTGGCGCCCGCGCTTGGCATCACACACCGC
TTTGTCGGTACGGAGCCGTTTTGTACCGTTACCGCCCAGTACAACCTTGATATGCGTTTCTGGCTGGAGACGCCAACGCT
TCCCGCCCCACCCATTACGCTGGTGGAAATAGAGCGGCTTTGCTTCCAGGAGACGCCGATATCCGCCTCCTGGGTACGCA
AGCTGCTGGTTAAACACGATCTCACGGCTATCGCGCCGCTGGTTCCCGACGCCACCCTGCGCTATTTGCAGGGCATGGTC
GAACGCCATCCGGGCAGCGCGGCAGCCCGTCAAAAGTCCCCCGTATTAGCAACAGGTGAAAAATGA

Upstream 100 bases:

>100_bases
AACATATACAGAAAAGTGGCAACAAGCATATCACCAGGATATTTCTTACTATGTTTGGCAATAATGTATTCACTCGGGTA
AAACGCTCTGAAAATAAAAA

Downstream 100 bases:

>100_bases
AAATAAACCAGCTAGCCGTCGCAGGCACGCTTGAGTCCGGCGATGTGATGATACGCATTGCGCCGCTCGATACGCAGGAT
ATTGACCTGCAAATTAACAG

Product: [citrate (pro-3S)-lyase] ligase

Products: NA

Alternate protein names: Acetate:SH-citrate lyase ligase; Citrate lyase synthetase [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MAEIAHFLKENDLSVDTTVEVFITVSRDDRLIACGGIAGNIIKCVAISESVRGEGLALTLATELINLAWERHCTHLFIYT
KTEYEALFKQCSFSTIASVPGVMVLMENSATRLKRYAESLATLRHEGKKIGCIVMNANPFTHGHRYLIQQAAAQCDWLHL
FLVKEDTSRFPYEDRLDLVLKGTTDIPRLTVHRGSEYIISRATFPCYFIKEQSVINHCYTEIDLKIFRQYLAPALGITHR
FVGTEPFCTVTAQYNLDMRFWLETPTLPAPPITLVEIERLCFQETPISASWVRKLLVKHDLTAIAPLVPDATLRYLQGMV
ERHPGSAAARQKSPVLATGEK

Sequences:

>Translated_341_residues
MAEIAHFLKENDLSVDTTVEVFITVSRDDRLIACGGIAGNIIKCVAISESVRGEGLALTLATELINLAWERHCTHLFIYT
KTEYEALFKQCSFSTIASVPGVMVLMENSATRLKRYAESLATLRHEGKKIGCIVMNANPFTHGHRYLIQQAAAQCDWLHL
FLVKEDTSRFPYEDRLDLVLKGTTDIPRLTVHRGSEYIISRATFPCYFIKEQSVINHCYTEIDLKIFRQYLAPALGITHR
FVGTEPFCTVTAQYNLDMRFWLETPTLPAPPITLVEIERLCFQETPISASWVRKLLVKHDLTAIAPLVPDATLRYLQGMV
ERHPGSAAARQKSPVLATGEK
>Mature_340_residues
AEIAHFLKENDLSVDTTVEVFITVSRDDRLIACGGIAGNIIKCVAISESVRGEGLALTLATELINLAWERHCTHLFIYTK
TEYEALFKQCSFSTIASVPGVMVLMENSATRLKRYAESLATLRHEGKKIGCIVMNANPFTHGHRYLIQQAAAQCDWLHLF
LVKEDTSRFPYEDRLDLVLKGTTDIPRLTVHRGSEYIISRATFPCYFIKEQSVINHCYTEIDLKIFRQYLAPALGITHRF
VGTEPFCTVTAQYNLDMRFWLETPTLPAPPITLVEIERLCFQETPISASWVRKLLVKHDLTAIAPLVPDATLRYLQGMVE
RHPGSAAARQKSPVLATGEK

Specific function: Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase [H]

COG id: COG3053

COG function: function code C; Citrate lyase synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI87081765, Length=334, Percent_Identity=86.5269461077844, Blast_Score=605, Evalue=1e-174,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005216
- InterPro:   IPR013166
- InterPro:   IPR004821
- InterPro:   IPR014729 [H]

Pfam domain/function: PF08218 Citrate_ly_lig [H]

EC number: =6.2.1.22 [H]

Molecular weight: Translated: 38430; Mature: 38299

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEIAHFLKENDLSVDTTVEVFITVSRDDRLIACGGIAGNIIKCVAISESVRGEGLALTL
CCHHHHHHHCCCCCEEEEEEEEEEECCCCCEEEECCCCCCEEEEEEECCCCCCCCEEEHH
ATELINLAWERHCTHLFIYTKTEYEALFKQCSFSTIASVPGVMVLMENSATRLKRYAESL
HHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCHHHHCCCEEEEEECCCHHHHHHHHHHH
ATLRHEGKKIGCIVMNANPFTHGHRYLIQQAAAQCDWLHLFLVKEDTSRFPYEDRLDLVL
HHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCEEEEE
KGTTDIPRLTVHRGSEYIISRATFPCYFIKEQSVINHCYTEIDLKIFRQYLAPALGITHR
ECCCCCCEEEEECCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVGTEPFCTVTAQYNLDMRFWLETPTLPAPPITLVEIERLCFQETPISASWVRKLLVKHD
HCCCCCEEEEEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHC
LTAIAPLVPDATLRYLQGMVERHPGSAAARQKSPVLATGEK
HHHHHHCCCHHHHHHHHHHHHCCCCCHHHHCCCCCEECCCC
>Mature Secondary Structure 
AEIAHFLKENDLSVDTTVEVFITVSRDDRLIACGGIAGNIIKCVAISESVRGEGLALTL
CHHHHHHHCCCCCEEEEEEEEEEECCCCCEEEECCCCCCEEEEEEECCCCCCCCEEEHH
ATELINLAWERHCTHLFIYTKTEYEALFKQCSFSTIASVPGVMVLMENSATRLKRYAESL
HHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCHHHHCCCEEEEEECCCHHHHHHHHHHH
ATLRHEGKKIGCIVMNANPFTHGHRYLIQQAAAQCDWLHLFLVKEDTSRFPYEDRLDLVL
HHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCEEEEE
KGTTDIPRLTVHRGSEYIISRATFPCYFIKEQSVINHCYTEIDLKIFRQYLAPALGITHR
ECCCCCCEEEEECCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVGTEPFCTVTAQYNLDMRFWLETPTLPAPPITLVEIERLCFQETPISASWVRKLLVKHD
HCCCCCEEEEEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHC
LTAIAPLVPDATLRYLQGMVERHPGSAAARQKSPVLATGEK
HHHHHHCCCHHHHHHHHHHHHCCCCCHHHHCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]