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The map label for this gene is kdgT2

Identifier: 29142617

GI number: 29142617

Start: 2281845

End: 2282798

Strand: Reverse

Name: kdgT2

Synonym: t2216

Alternate gene names: 29142617

Gene position: 2282798-2281845 (Counterclockwise)

Preceding gene: 29142618

Following gene: 29142616

Centisome position: 47.64

GC content: 52.41

Gene sequence:

>954_bases
ATGAAAATTAAAAAAACACTGGAACGTTTTCCTGGTGGTATGATGGTTGTACCGCTGATCATCGGCGCCTTGTTTAAAAC
TTTTGCGCCGGAGGCGCTGGAAATAGGCGGTTTTGTCATCTCTATTTCGCATGGCGCAATGGCGATTTTAGGCATGTTTT
TAGTCTGTATGGGCGCGGATATCCAGTTTAAAGCCGCGCCGAAAGCGTTGAAAAAAGGCGCTGCGATCACCTTTGCGAAA
TTTGCCAGCGGCGTGATTATTGGCATTCTGGTCGGGAAATTTTGCGGCCCGGATGGGTTATTAGGTCTGTCGGCTTTAGC
GATTATTTCGGCGATGACCAACTCGAACAGTGGGTTATATGCCGCGTTGGTGGGGGAGTACGGCGATGAAACCGACGGCG
GCGCGATTGCGGTAATATCGTTGAACGATGGTCCCTTTTTCACCATGCTGGCGTTAGGATCGGCAGGCATGGTGTCGATA
CCCTTTATGAATCTGGTGGCGGTTATTATTCCCATTATCATTGGCATGATTTTGGGCAATCTGGATGAGGACATGCGCAA
GTTTCTTAAACAGGGCAGCGTGGTAACGATTCCCTTTTTTGCCTTTGGGTTAGGATACAGTATTGATTTCGCAAGACTTA
TCACGGCAGGTTCTTCAGGCATTTTACTGGGACTCATGACGGTGGCGATTGGCGGATTTTTTAATATTTTCGCCGATCGT
GTGACGGGAGGCAGCGGCGTGGCAGGCGCGGCGGTATCCACCACCTCTGGCAACGCCGTCGCGACGCCAGCGGCAATCGC
GCTGCTCGATCCGCATTTTACCGACCTGGCGTCGACGGCGGCGGCGCAGGTGGCGGCCTCGACGATTATTACCGCTCTGT
GCGCCCCCTTCCTGACCGTATGGATAAAAAAACGCTACGATCGTAAACTGAACCCAGCCGCCGCAGGCGGTTAG

Upstream 100 bases:

>100_bases
GATTTAGGTCATAACGAATTCTCTATTTATAAGATCGCGCCGACGTTCTGATACCAAATCGGGCAGCACAAGCTGTCCGG
TTATCTCCTGGGAATAAGCT

Downstream 100 bases:

>100_bases
CGTTTCGGCGGAAAATAAATCACGACGGGCGGTCTCGCCCGTTTATAAACCAACAGGATGGTGAGTGATGAATAAGACGA
AAGATATAGCCGCATCTCCT

Product: 2-keto-3-deoxygluconate permease

Products: Proton [Cytoplasm]; 2-dehydro-3-deoxy-D-gluconate [Cytoplasm] [C]

Alternate protein names: KDG permease 2

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MKIKKTLERFPGGMMVVPLIIGALFKTFAPEALEIGGFVISISHGAMAILGMFLVCMGADIQFKAAPKALKKGAAITFAK
FASGVIIGILVGKFCGPDGLLGLSALAIISAMTNSNSGLYAALVGEYGDETDGGAIAVISLNDGPFFTMLALGSAGMVSI
PFMNLVAVIIPIIIGMILGNLDEDMRKFLKQGSVVTIPFFAFGLGYSIDFARLITAGSSGILLGLMTVAIGGFFNIFADR
VTGGSGVAGAAVSTTSGNAVATPAAIALLDPHFTDLASTAAAQVAASTIITALCAPFLTVWIKKRYDRKLNPAAAGG

Sequences:

>Translated_317_residues
MKIKKTLERFPGGMMVVPLIIGALFKTFAPEALEIGGFVISISHGAMAILGMFLVCMGADIQFKAAPKALKKGAAITFAK
FASGVIIGILVGKFCGPDGLLGLSALAIISAMTNSNSGLYAALVGEYGDETDGGAIAVISLNDGPFFTMLALGSAGMVSI
PFMNLVAVIIPIIIGMILGNLDEDMRKFLKQGSVVTIPFFAFGLGYSIDFARLITAGSSGILLGLMTVAIGGFFNIFADR
VTGGSGVAGAAVSTTSGNAVATPAAIALLDPHFTDLASTAAAQVAASTIITALCAPFLTVWIKKRYDRKLNPAAAGG
>Mature_317_residues
MKIKKTLERFPGGMMVVPLIIGALFKTFAPEALEIGGFVISISHGAMAILGMFLVCMGADIQFKAAPKALKKGAAITFAK
FASGVIIGILVGKFCGPDGLLGLSALAIISAMTNSNSGLYAALVGEYGDETDGGAIAVISLNDGPFFTMLALGSAGMVSI
PFMNLVAVIIPIIIGMILGNLDEDMRKFLKQGSVVTIPFFAFGLGYSIDFARLITAGSSGILLGLMTVAIGGFFNIFADR
VTGGSGVAGAAVSTTSGNAVATPAAIALLDPHFTDLASTAAAQVAASTIITALCAPFLTVWIKKRYDRKLNPAAAGG

Specific function: The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdgT transporter family

Homologues:

Organism=Escherichia coli, GI87082349, Length=316, Percent_Identity=38.2911392405063, Blast_Score=187, Evalue=6e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDGT2_SALTI (Q8Z8H3)

Other databases:

- EMBL:   AL627267
- EMBL:   AE014613
- RefSeq:   NP_455227.1
- RefSeq:   NP_805959.1
- GeneID:   1067247
- GeneID:   1247160
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t2216
- KEGG:   sty:STY0702
- HOGENOM:   HBG322377
- OMA:   IGANSSI
- ProtClustDB:   PRK05274
- BioCyc:   SENT209261:T2216-MONOMER
- BioCyc:   SENT220341:STY0702-MONOMER
- HAMAP:   MF_00070
- InterPro:   IPR004684
- ProDom:   PD024513

Pfam domain/function: PF03812 KdgT

EC number: NA

Molecular weight: Translated: 32395; Mature: 32395

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf87142c)-; HASH(0xfafb908)-; HASH(0xfe562e4)-; HASH(0xfecfc38)-; HASH(0xfa50af0)-; HASH(0xf0ee0b8)-; HASH(0xf7f271c)-; HASH(0xfa92984)-; HASH(0xf627c2c)-; HASH(0xfac3ef8)-;

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKKTLERFPGGMMVVPLIIGALFKTFAPEALEIGGFVISISHGAMAILGMFLVCMGAD
CCCHHHHHHCCCCEEHHHHHHHHHHHHHCCCHHHHCCEEEEECCCHHHHHHHHHHHHCCC
IQFKAAPKALKKGAAITFAKFASGVIIGILVGKFCGPDGLLGLSALAIISAMTNSNSGLY
CEECCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEE
AALVGEYGDETDGGAIAVISLNDGPFFTMLALGSAGMVSIPFMNLVAVIIPIIIGMILGN
EEEECCCCCCCCCCEEEEEEECCCCEEEHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCC
LDEDMRKFLKQGSVVTIPFFAFGLGYSIDFARLITAGSSGILLGLMTVAIGGFFNIFADR
CCHHHHHHHHCCCEEEEHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VTGGSGVAGAAVSTTSGNAVATPAAIALLDPHFTDLASTAAAQVAASTIITALCAPFLTV
CCCCCCCCCCEEECCCCCCEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WIKKRYDRKLNPAAAGG
HHHHHHCCCCCCCCCCH
>Mature Secondary Structure
MKIKKTLERFPGGMMVVPLIIGALFKTFAPEALEIGGFVISISHGAMAILGMFLVCMGAD
CCCHHHHHHCCCCEEHHHHHHHHHHHHHCCCHHHHCCEEEEECCCHHHHHHHHHHHHCCC
IQFKAAPKALKKGAAITFAKFASGVIIGILVGKFCGPDGLLGLSALAIISAMTNSNSGLY
CEECCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEE
AALVGEYGDETDGGAIAVISLNDGPFFTMLALGSAGMVSIPFMNLVAVIIPIIIGMILGN
EEEECCCCCCCCCCEEEEEEECCCCEEEHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCC
LDEDMRKFLKQGSVVTIPFFAFGLGYSIDFARLITAGSSGILLGLMTVAIGGFFNIFADR
CCHHHHHHHHCCCEEEEHHHHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VTGGSGVAGAAVSTTSGNAVATPAAIALLDPHFTDLASTAAAQVAASTIITALCAPFLTV
CCCCCCCCCCEEECCCCCCEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WIKKRYDRKLNPAAAGG
HHHHHHCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 2-dehydro-3-deoxy-D-gluconate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 2-dehydro-3-deoxy-D-gluconate [Periplasm] = Proton [Cytoplasm] + 2-dehydro-3-deoxy-D-gluconate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504