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The map label for this gene is pgm [H]

Identifier: 29142585

GI number: 29142585

Start: 2243687

End: 2245327

Strand: Reverse

Name: pgm [H]

Synonym: t2177

Alternate gene names: 29142585

Gene position: 2245327-2243687 (Counterclockwise)

Preceding gene: 29142586

Following gene: 29142577

Centisome position: 46.86

GC content: 56.12

Gene sequence:

>1641_bases
ATGGCAATCCACAACCGCGCAGGACAACCCGCGCAACAGAGTGATTTGATTAACGTCGCCCAACTGACAGCGCAGTATTA
TGTACTGAAACCGGAGGCAGGGAATGCAGAACATGCCGTGAAATTTGGCACTTCCGGCCATCGCGGCAGCGCAGGTCGTC
ACAGTTTCAACGAACCGCATATTCTGGCGATCGCCCAGGCGATTGCTGAAGAGCGGGCGAAAAATGGCATTACCGGCCCC
TGCTATGTGGGGAAAGACACCCATGCGCTCTCGGAACCGGCCTTCATTTCCGTGCTGGAAGTGCTGGCGGCAAACGGCGT
AGACGTTATCGTGCAGGAAAATAATGGCTTCACGCCAACGCCTGCCGTGTCAAATGCTATCCTGGTCCATAACAAAAAAG
GCGGCCCGCTGGCAGATGGTATTGTCATTACACCGTCGCACAACCCGCCGGAAGATGGCGGTATTAAATATAATCCGCCC
AATGGCGGCCCGGCGGATACCAACGTCACTAAAGTGGTAGAAGATCGCGCCAATGCGCTGCTGGCGGATGGCCTGCAAGG
CGTTAAGCGCATCTCTCTGGATGCGGCAATGGCCTCGGGTCACGTTAAAGCGGTAGATCTGGTACAGCCGTTTGTCGAAG
GGCTGGCGGATATCGTTGATATGGCGGCGATTCAGAAAGCCGGTCTGACGCTGGGCGTTGATCCGCTGGGCGGCTCTGGT
ATTGAATACTGGAAACGTATCGCTGAGCATTACAAGCTTAACCTGACGTTAGTCAACGATCAGGTTGATCAAACCTTCCG
CTTTATGCACCTTGATAAAGATGGCGCGATCCGCATGGATTGCTCCTCCGAATGTGCGATGGCGGGTTTGCTGGCGCTGC
GTGACAAGTTTGACCTGGCCTTCGCCAACGACCCGGACTACGACCGTCATGGCATCGTGACGCCTGCAGGGCTGATGAAC
CCGAACCATTATCTGGCGGTCGCCATTAACTATCTGTTCCAGCATCGTCCGCTGTGGGGCAAAGACGTGGCTGTCGGTAA
AACGCTGGTCTCTTCCGCGATGATTGACCGCGTGGTGAATGATTTGGGACGCAAGCTGGTAGAAGTGCCGGTTGGCTTCA
AATGGTTTGTTGACGGTTTGTTCGACGGCAGCTTTGGTTTCGGCGGGGAAGAGAGCGCGGGCGCTTCGTTCCTGCGTTTC
GACGGTACGCCGTGGTCTACCGATAAAGACGGGATCATCATGTGCCTGCTGGCGGCGGAAATCACCGCCGTTACCGGGAA
AAACCCGCAAGAGCATTACAATGAACTGGCAGCGCGTTTTGGCGCGCCGAGCTATAACCGTCTGCAGGCGGCAGCGACCT
CGGCCCAGAAAGCGGCATTGTCTAAACTGTCTCCGGAAATGGTGAGCGCCAGCACGCTGGCAGGCGACCCGATTACCGCG
CGTCTTACCGCAGCGCCGGGTAATGGCGCATCGATTGGCGGCCTGAAGGTAATGACCGACAACGGCTGGTTCGCCGCGCG
TCCATCCGGTACGGAAGACGCTTACAAGATCTATTGCGAAAGCTTCCTGGGGGAAGAACATCGCAAGCAGATTGAGAAAG
AAGCCGTTGAAATCGTTAGCGAAGTATTGAAAAACGCCTGA

Upstream 100 bases:

>100_bases
CAGCATGATCGAACACATCATGCAGTCAATGCAATTCCCGGCGGAATTGATTGAAAAGGTTTGCGGAACAATTTAATCCT
TGCATTAGAAGGACCAGGCA

Downstream 100 bases:

>100_bases
TGGGCGATATGGAAGAAAAAGGAGCCTTACGGCTCCTTTTTTGTATTAACGGCGCTGCGCTTATCAGGCCTGTAAACCGC
CTCCAGGCCGGATAAGGCGC

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 546; Mature: 545

Protein sequence:

>546_residues
MAIHNRAGQPAQQSDLINVAQLTAQYYVLKPEAGNAEHAVKFGTSGHRGSAGRHSFNEPHILAIAQAIAEERAKNGITGP
CYVGKDTHALSEPAFISVLEVLAANGVDVIVQENNGFTPTPAVSNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPP
NGGPADTNVTKVVEDRANALLADGLQGVKRISLDAAMASGHVKAVDLVQPFVEGLADIVDMAAIQKAGLTLGVDPLGGSG
IEYWKRIAEHYKLNLTLVNDQVDQTFRFMHLDKDGAIRMDCSSECAMAGLLALRDKFDLAFANDPDYDRHGIVTPAGLMN
PNHYLAVAINYLFQHRPLWGKDVAVGKTLVSSAMIDRVVNDLGRKLVEVPVGFKWFVDGLFDGSFGFGGEESAGASFLRF
DGTPWSTDKDGIIMCLLAAEITAVTGKNPQEHYNELAARFGAPSYNRLQAAATSAQKAALSKLSPEMVSASTLAGDPITA
RLTAAPGNGASIGGLKVMTDNGWFAARPSGTEDAYKIYCESFLGEEHRKQIEKEAVEIVSEVLKNA

Sequences:

>Translated_546_residues
MAIHNRAGQPAQQSDLINVAQLTAQYYVLKPEAGNAEHAVKFGTSGHRGSAGRHSFNEPHILAIAQAIAEERAKNGITGP
CYVGKDTHALSEPAFISVLEVLAANGVDVIVQENNGFTPTPAVSNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPP
NGGPADTNVTKVVEDRANALLADGLQGVKRISLDAAMASGHVKAVDLVQPFVEGLADIVDMAAIQKAGLTLGVDPLGGSG
IEYWKRIAEHYKLNLTLVNDQVDQTFRFMHLDKDGAIRMDCSSECAMAGLLALRDKFDLAFANDPDYDRHGIVTPAGLMN
PNHYLAVAINYLFQHRPLWGKDVAVGKTLVSSAMIDRVVNDLGRKLVEVPVGFKWFVDGLFDGSFGFGGEESAGASFLRF
DGTPWSTDKDGIIMCLLAAEITAVTGKNPQEHYNELAARFGAPSYNRLQAAATSAQKAALSKLSPEMVSASTLAGDPITA
RLTAAPGNGASIGGLKVMTDNGWFAARPSGTEDAYKIYCESFLGEEHRKQIEKEAVEIVSEVLKNA
>Mature_545_residues
AIHNRAGQPAQQSDLINVAQLTAQYYVLKPEAGNAEHAVKFGTSGHRGSAGRHSFNEPHILAIAQAIAEERAKNGITGPC
YVGKDTHALSEPAFISVLEVLAANGVDVIVQENNGFTPTPAVSNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPPN
GGPADTNVTKVVEDRANALLADGLQGVKRISLDAAMASGHVKAVDLVQPFVEGLADIVDMAAIQKAGLTLGVDPLGGSGI
EYWKRIAEHYKLNLTLVNDQVDQTFRFMHLDKDGAIRMDCSSECAMAGLLALRDKFDLAFANDPDYDRHGIVTPAGLMNP
NHYLAVAINYLFQHRPLWGKDVAVGKTLVSSAMIDRVVNDLGRKLVEVPVGFKWFVDGLFDGSFGFGGEESAGASFLRFD
GTPWSTDKDGIIMCLLAAEITAVTGKNPQEHYNELAARFGAPSYNRLQAAATSAQKAALSKLSPEMVSASTLAGDPITAR
LTAAPGNGASIGGLKVMTDNGWFAARPSGTEDAYKIYCESFLGEEHRKQIEKEAVEIVSEVLKNA

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI133922562, Length=416, Percent_Identity=25.2403846153846, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI290463102, Length=451, Percent_Identity=26.8292682926829, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI21361621, Length=403, Percent_Identity=27.5434243176179, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1786904, Length=546, Percent_Identity=97.985347985348, Blast_Score=1082, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535441, Length=568, Percent_Identity=26.056338028169, Blast_Score=87, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323752, Length=562, Percent_Identity=25.9786476868327, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322722, Length=535, Percent_Identity=27.1028037383178, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17864244, Length=452, Percent_Identity=28.9823008849558, Blast_Score=108, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 58132; Mature: 58001

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIHNRAGQPAQQSDLINVAQLTAQYYVLKPEAGNAEHAVKFGTSGHRGSAGRHSFNEPH
CCCCCCCCCCCHHHHHHHHHHHCEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCH
ILAIAQAIAEERAKNGITGPCYVGKDTHALSEPAFISVLEVLAANGVDVIVQENNGFTPT
HHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCC
PAVSNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPPNGGPADTNVTKVVEDRANAL
CCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHH
LADGLQGVKRISLDAAMASGHVKAVDLVQPFVEGLADIVDMAAIQKAGLTLGVDPLGGSG
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCH
IEYWKRIAEHYKLNLTLVNDQVDQTFRFMHLDKDGAIRMDCSSECAMAGLLALRDKFDLA
HHHHHHHHHHEEEEEEEECCCHHHHEEEEEECCCCCEEECCCCHHHHHHHHHHHHCCCEE
FANDPDYDRHGIVTPAGLMNPNHYLAVAINYLFQHRPLWGKDVAVGKTLVSSAMIDRVVN
ECCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
DLGRKLVEVPVGFKWFVDGLFDGSFGFGGEESAGASFLRFDGTPWSTDKDGIIMCLLAAE
HHHHHHHHCCCCCEEHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEHHH
ITAVTGKNPQEHYNELAARFGAPSYNRLQAAATSAQKAALSKLSPEMVSASTLAGDPITA
HHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEE
RLTAAPGNGASIGGLKVMTDNGWFAARPSGTEDAYKIYCESFLGEEHRKQIEKEAVEIVS
EEEECCCCCCCCCCEEEEECCCEEEECCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHH
EVLKNA
HHHHCC
>Mature Secondary Structure 
AIHNRAGQPAQQSDLINVAQLTAQYYVLKPEAGNAEHAVKFGTSGHRGSAGRHSFNEPH
CCCCCCCCCCHHHHHHHHHHHCEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCH
ILAIAQAIAEERAKNGITGPCYVGKDTHALSEPAFISVLEVLAANGVDVIVQENNGFTPT
HHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCC
PAVSNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPPNGGPADTNVTKVVEDRANAL
CCCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHH
LADGLQGVKRISLDAAMASGHVKAVDLVQPFVEGLADIVDMAAIQKAGLTLGVDPLGGSG
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCH
IEYWKRIAEHYKLNLTLVNDQVDQTFRFMHLDKDGAIRMDCSSECAMAGLLALRDKFDLA
HHHHHHHHHHEEEEEEEECCCHHHHEEEEEECCCCCEEECCCCHHHHHHHHHHHHCCCEE
FANDPDYDRHGIVTPAGLMNPNHYLAVAINYLFQHRPLWGKDVAVGKTLVSSAMIDRVVN
ECCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
DLGRKLVEVPVGFKWFVDGLFDGSFGFGGEESAGASFLRFDGTPWSTDKDGIIMCLLAAE
HHHHHHHHCCCCCEEHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEEHHH
ITAVTGKNPQEHYNELAARFGAPSYNRLQAAATSAQKAALSKLSPEMVSASTLAGDPITA
HHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEE
RLTAAPGNGASIGGLKVMTDNGWFAARPSGTEDAYKIYCESFLGEEHRKQIEKEAVEIVS
EEEECCCCCCCCCCEEEEECCCEEEECCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHH
EVLKNA
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083177; 8905232; 9278503; 8011018 [H]