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The map label for this gene is supH [H]

Identifier: 29142468

GI number: 29142468

Start: 2107475

End: 2108284

Strand: Reverse

Name: supH [H]

Synonym: t2047

Alternate gene names: 29142468

Gene position: 2108284-2107475 (Counterclockwise)

Preceding gene: 29142470

Following gene: 29142463

Centisome position: 44.0

GC content: 49.26

Gene sequence:

>810_bases
ATGACCGTTAACGTTGTCGTTACCGATATGGACGGCACTTTTCTCGACGATGCCAAGCAGTACGATCGTGTACGCTTCAT
GGCGCAATACCAGGAACTGAAAAAACGTAATATCGAATTTGTGGTCGCCAGCGGTAATCAGTACTATCAGTTGATCTCCT
TCTTCCCCGAGCTGAAAGACGAAATTTCCTTCGTCGCAGAAAATGGCGCGCTGGTGTATGAACATGGCAAGCAGTTGTTT
CACGGAGAGCTAACCCGGCATGAATCGCGTATTGTGATTGGCGAACTGCTGAAGGATAAGCAGCTTAACTTCGTCGCCTG
CGGTCTGAAAAGCGCTTATGTCAGCAAAAACGCTCCCGAGACTTTCGTGGCGCTGATGGCCAAACATTATCACCGCCTGC
AGCCGGTAAACGATTATCACGACATTGACGATATCCTGTTTAAGTTCTCCCTGAATTTGCCCGATGAACAAATTCCGCTG
GTTATCGACAAACTGCACGTATCTCTGGATGGCATCATGAAGCCTGTCACCAGCGGCTTCGGTTTTATCGACCTGATTAT
CCCGGGACTGCATAAAGCGAATGGCATCAGTCGTCTGTTAAAGCGCTGGAACAGGTCGCCACAGAATGTCGTCGCCATTG
GCGACAGCGGTAATGATGCGGAAATGTTGAAAATGGCGCATTACTCTTTTGCCATGGGCAATGCCGCAGACAATATCAAA
GCGCTTTCACGTTATCACACTGATGATAATAACCATCAAGGCGCGCTCAACGTCATTCAGGCCGTGCTTGACGGCACCGA
TCCCTTCTGA

Upstream 100 bases:

>100_bases
TTCCTTTCGTTCAGCCACTTTTCATTCGAAATAAATTTGTGGTTCTGCTCACATTGTTATTAAAATGTTTCTGGTCGCAG
TTACAGCCAGGAGCTTAAGT

Downstream 100 bases:

>100_bases
TTAACAGGCCTGCGTAGGCCTGTTAAGCGTAGCGCCATCAGGCAGTTCGGACATATTGCCGATGGCGCCTGGGCAAATTA
CAGCATATGTTCGGTACGGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MTVNVVVTDMDGTFLDDAKQYDRVRFMAQYQELKKRNIEFVVASGNQYYQLISFFPELKDEISFVAENGALVYEHGKQLF
HGELTRHESRIVIGELLKDKQLNFVACGLKSAYVSKNAPETFVALMAKHYHRLQPVNDYHDIDDILFKFSLNLPDEQIPL
VIDKLHVSLDGIMKPVTSGFGFIDLIIPGLHKANGISRLLKRWNRSPQNVVAIGDSGNDAEMLKMAHYSFAMGNAADNIK
ALSRYHTDDNNHQGALNVIQAVLDGTDPF

Sequences:

>Translated_269_residues
MTVNVVVTDMDGTFLDDAKQYDRVRFMAQYQELKKRNIEFVVASGNQYYQLISFFPELKDEISFVAENGALVYEHGKQLF
HGELTRHESRIVIGELLKDKQLNFVACGLKSAYVSKNAPETFVALMAKHYHRLQPVNDYHDIDDILFKFSLNLPDEQIPL
VIDKLHVSLDGIMKPVTSGFGFIDLIIPGLHKANGISRLLKRWNRSPQNVVAIGDSGNDAEMLKMAHYSFAMGNAADNIK
ALSRYHTDDNNHQGALNVIQAVLDGTDPF
>Mature_268_residues
TVNVVVTDMDGTFLDDAKQYDRVRFMAQYQELKKRNIEFVVASGNQYYQLISFFPELKDEISFVAENGALVYEHGKQLFH
GELTRHESRIVIGELLKDKQLNFVACGLKSAYVSKNAPETFVALMAKHYHRLQPVNDYHDIDDILFKFSLNLPDEQIPLV
IDKLHVSLDGIMKPVTSGFGFIDLIIPGLHKANGISRLLKRWNRSPQNVVAIGDSGNDAEMLKMAHYSFAMGNAADNIKA
LSRYHTDDNNHQGALNVIQAVLDGTDPF

Specific function: Catalyzes the hydrolysis of sugar phosphate to sugar and inorganic phosphate. Has a wide substrate specificity catalyzing the hydrolysis of fructose-1-P most efficiently, but it remains uncertain if this is the real substrate in vivo [H]

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family. SupH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787043, Length=269, Percent_Identity=88.8475836431227, Blast_Score=502, Evalue=1e-144,
Organism=Escherichia coli, GI87081790, Length=269, Percent_Identity=49.4423791821561, Blast_Score=270, Evalue=5e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.23 [H]

Molecular weight: Translated: 30359; Mature: 30228

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVNVVVTDMDGTFLDDAKQYDRVRFMAQYQELKKRNIEFVVASGNQYYQLISFFPELKD
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHH
EISFVAENGALVYEHGKQLFHGELTRHESRIVIGELLKDKQLNFVACGLKSAYVSKNAPE
HHHHHHCCCEEEEECCHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEECCHHHHHCCCCHH
TFVALMAKHYHRLQPVNDYHDIDDILFKFSLNLPDEQIPLVIDKLHVSLDGIMKPVTSGF
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
GFIDLIIPGLHKANGISRLLKRWNRSPQNVVAIGDSGNDAEMLKMAHYSFAMGNAADNIK
CCHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHH
ALSRYHTDDNNHQGALNVIQAVLDGTDPF
HHHHHCCCCCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TVNVVVTDMDGTFLDDAKQYDRVRFMAQYQELKKRNIEFVVASGNQYYQLISFFPELKD
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHH
EISFVAENGALVYEHGKQLFHGELTRHESRIVIGELLKDKQLNFVACGLKSAYVSKNAPE
HHHHHHCCCEEEEECCHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEECCHHHHHCCCCHH
TFVALMAKHYHRLQPVNDYHDIDDILFKFSLNLPDEQIPLVIDKLHVSLDGIMKPVTSGF
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
GFIDLIIPGLHKANGISRLLKRWNRSPQNVVAIGDSGNDAEMLKMAHYSFAMGNAADNIK
CCHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHH
ALSRYHTDDNNHQGALNVIQAVLDGTDPF
HHHHHCCCCCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]