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The map label for this gene is ybjY [H]

Identifier: 29142413

GI number: 29142413

Start: 2049649

End: 2050767

Strand: Reverse

Name: ybjY [H]

Synonym: t1992

Alternate gene names: 29142413

Gene position: 2050767-2049649 (Counterclockwise)

Preceding gene: 29142415

Following gene: 29142412

Centisome position: 42.8

GC content: 53.17

Gene sequence:

>1119_bases
ATGCGTGCTAAGGGAAAGAAATTTAAAAAGCGTTATCTGGTCATTATTTTAATTCTTTTAGTGGGGGGGATGGTTAGCTG
GCGAATGATAAATGCGCCGCTGCCAACTTATCAGACATTAATCGTGCGGCCAGGCGATCTTGAACAGAGTGTACTGGCGA
CTGGAAAACTGGACGCGTTGCGTAAAGTGGATGTCGGCGCGCAGGTGAGCGGCCAGTTGAAAACGCTGCTGGTCTCCATT
GGCGATAACGTTAAAAAAGATCAGCTACTCGGCGTGATTGACCCAGATCAGGCGGAGAACCAGATAAAAGAGGTCGAGGC
CACCCTGATGGAGCTGAACGCGGAGCGTCAGCAGGCAGCCGCTGAGTTAAAGCTGGCGCGGGTTACGCTGGCGCGCCAGC
AGCAGTTAGCTAAGACTCAGGCGGTATCGCAACAGGATCTGGATACTGCGGCGACGGAGTTGGCGGTTAAACAGGCGCGT
ATTGGCACCATAGATGCCCAGATCAAACGTAATCGGGCCTCGTTGGACACCGCGAAAACCAACCTGGAATATACCCGTAT
TGTCGCCCCCATGGCGGGGGAAGTGACGCAAATCACTACCCTGCAAGGACAAACGGTGATTGCAGCTCAGCAGGCGCCCA
ATATTCTGACGCTGGCGGATATGAGCACCATGCTGGTAAAAGCGCAGGTCTCGGAAGCGGACGTGATCCATCTTCGGGCG
GGGCAGAAAGCATGGTTCACCATTGCAGGCGATCCGCAAACGCGCTATGAAGGCGTTTTAAAAGATATTCTGCCGACGCC
GGAAAAGATCAACGACGCTATTTTTTATTACGCCCGGTTTGAAGTGCCGAATCCCAAAAGAATCTTGCGTCTTGATATGA
CCGCACAGGTTTATATTCAACTCATGGATGTCAAAAATGTGCTGATTATTCCTCTCGCCGCGCTTGGCGAGCCGGTGGGC
GGTAATCGTTATAAAGTGGCGCTGTTGCGTAACGGCGAAAAACGTGAGCGCGAAGTGGTCATTGGCGAGCGTAACGATAC
AGACGTGGAAGTGGTTAAAGGTCTGGAAGCGGGCGATGAGGTGATCATCGGCGAGAGCAGGCCAGGAGCGACGCCATGA

Upstream 100 bases:

>100_bases
ACATTAACCAATCGTCAATACAGCCGGCGCTATCTTTATTGCGTCAGGTTTGTTTAGATACGGTTTACTTTCTGGTTAAA
ATTTTGCCGTCAGGGTTTCT

Downstream 100 bases:

>100_bases
CGGCATTGCTTGAACTGTGCAATGTGAGCCGCAGCTACCCCTCCGGAGAAGAGCAGGTGGCGGTGTTGAAAGATATCTCC
CTGCAAATCCACGCCGGGGA

Product: macrolide transporter subunit MacA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MRAKGKKFKKRYLVIILILLVGGMVSWRMINAPLPTYQTLIVRPGDLEQSVLATGKLDALRKVDVGAQVSGQLKTLLVSI
GDNVKKDQLLGVIDPDQAENQIKEVEATLMELNAERQQAAAELKLARVTLARQQQLAKTQAVSQQDLDTAATELAVKQAR
IGTIDAQIKRNRASLDTAKTNLEYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLRA
GQKAWFTIAGDPQTRYEGVLKDILPTPEKINDAIFYYARFEVPNPKRILRLDMTAQVYIQLMDVKNVLIIPLAALGEPVG
GNRYKVALLRNGEKREREVVIGERNDTDVEVVKGLEAGDEVIIGESRPGATP

Sequences:

>Translated_372_residues
MRAKGKKFKKRYLVIILILLVGGMVSWRMINAPLPTYQTLIVRPGDLEQSVLATGKLDALRKVDVGAQVSGQLKTLLVSI
GDNVKKDQLLGVIDPDQAENQIKEVEATLMELNAERQQAAAELKLARVTLARQQQLAKTQAVSQQDLDTAATELAVKQAR
IGTIDAQIKRNRASLDTAKTNLEYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLRA
GQKAWFTIAGDPQTRYEGVLKDILPTPEKINDAIFYYARFEVPNPKRILRLDMTAQVYIQLMDVKNVLIIPLAALGEPVG
GNRYKVALLRNGEKREREVVIGERNDTDVEVVKGLEAGDEVIIGESRPGATP
>Mature_372_residues
MRAKGKKFKKRYLVIILILLVGGMVSWRMINAPLPTYQTLIVRPGDLEQSVLATGKLDALRKVDVGAQVSGQLKTLLVSI
GDNVKKDQLLGVIDPDQAENQIKEVEATLMELNAERQQAAAELKLARVTLARQQQLAKTQAVSQQDLDTAATELAVKQAR
IGTIDAQIKRNRASLDTAKTNLEYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLRA
GQKAWFTIAGDPQTRYEGVLKDILPTPEKINDAIFYYARFEVPNPKRILRLDMTAQVYIQLMDVKNVLIIPLAALGEPVG
GNRYKVALLRNGEKREREVVIGERNDTDVEVVKGLEAGDEVIIGESRPGATP

Specific function: Efflux transporter for macrolide antibiotics [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87081796, Length=367, Percent_Identity=83.1062670299727, Blast_Score=622, Evalue=1e-180,
Organism=Escherichia coli, GI87082036, Length=346, Percent_Identity=26.5895953757225, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789929, Length=383, Percent_Identity=22.7154046997389, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40846; Mature: 40846

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAKGKKFKKRYLVIILILLVGGMVSWRMINAPLPTYQTLIVRPGDLEQSVLATGKLDAL
CCCCCHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCCEEEEECCCCCCHHHHHCCCHHHH
RKVDVGAQVSGQLKTLLVSIGDNVKKDQLLGVIDPDQAENQIKEVEATLMELNAERQQAA
HHCCCCCCCCCCHHHHHHHHCCCCCCHHEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHH
AELKLARVTLARQQQLAKTQAVSQQDLDTAATELAVKQARIGTIDAQIKRNRASLDTAKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHCCHHCHHHHC
NLEYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLRA
CCEEEEEECCCCCCCEEEEEECCCEEEEECCCCCEEEEHHHHHHHEEEECCCCCEEEEEC
GQKAWFTIAGDPQTRYEGVLKDILPTPEKINDAIFYYARFEVPNPKRILRLDMTAQVYIQ
CCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCEEEEECCHHEEEEE
LMDVKNVLIIPLAALGEPVGGNRYKVALLRNGEKREREVVIGERNDTDVEVVKGLEAGDE
EECCCCEEEEEHHHHCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCHHHHHHCCCCCCE
VIIGESRPGATP
EEEECCCCCCCC
>Mature Secondary Structure
MRAKGKKFKKRYLVIILILLVGGMVSWRMINAPLPTYQTLIVRPGDLEQSVLATGKLDAL
CCCCCHHHHHHHHHHHHHHHHCCHHEEEEECCCCCCCEEEEECCCCCCHHHHHCCCHHHH
RKVDVGAQVSGQLKTLLVSIGDNVKKDQLLGVIDPDQAENQIKEVEATLMELNAERQQAA
HHCCCCCCCCCCHHHHHHHHCCCCCCHHEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHH
AELKLARVTLARQQQLAKTQAVSQQDLDTAATELAVKQARIGTIDAQIKRNRASLDTAKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHHHCCHHCHHHHC
NLEYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLRA
CCEEEEEECCCCCCCEEEEEECCCEEEEECCCCCEEEEHHHHHHHEEEECCCCCEEEEEC
GQKAWFTIAGDPQTRYEGVLKDILPTPEKINDAIFYYARFEVPNPKRILRLDMTAQVYIQ
CCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCEEEEECCHHEEEEE
LMDVKNVLIIPLAALGEPVGGNRYKVALLRNGEKREREVVIGERNDTDVEVVKGLEAGDE
EECCCCEEEEEHHHHCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCHHHHHHCCCCCCE
VIIGESRPGATP
EEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]