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The map label for this gene is sapB [H]

Identifier: 29142038

GI number: 29142038

Start: 1656717

End: 1657682

Strand: Direct

Name: sapB [H]

Synonym: t1598

Alternate gene names: 29142038

Gene position: 1656717-1657682 (Clockwise)

Preceding gene: 29142037

Following gene: 29142042

Centisome position: 34.57

GC content: 52.9

Gene sequence:

>966_bases
ATGATTATCTTCACCCTGCGTCGGTTATTGCTGTTGCTGGTGACGCTATTCTTCCTGACCTTTATCGGCTTTAGCCTGAG
CTATTTTACGCCGCACGCGCCGCTACAAGGCGCATCATTATGGAATGCCTGGGTTTTCTGGTTCAACGGTCTGCTGCACT
GGGACTTTGGCGTGTCCAGCATTAACGGCCAGCTGATCTCCGAACAGCTTAAAGAGGTGTTTCCCGCCACGATGGAGCTG
TGCATTCTCGCCTTTGGTTTTGCGCTGATGGTCGGCATCCCGGTCGGGATGCTGGCTGGCGTGACGCGTAGCAAATGGCC
GGATCGTTTTATCAGCGCGCTGGCGCTATTAGGTTTCTCAATTCCGGTTTTCTGGCTGGCGCTTCTGCTCACACTGTTCT
TTTCGCTCACACTGGGGTGGCTGCCGGTATCCGGGCGATTTGACCTGCTTTATGAAGTTAAACCGGTTACCGGTTTCGCC
ATCATTGACGCCTGGATTTCAGATTCGCCGTGGCGTGATGAAATGGTAATGAGCGCCATACGACATATGGTTTTACCGGT
GCTCACGCTTTCCGTCGCGCCGACCACAGAGGTGATCCGCCTGATGCGAATCAGCACTATTGAGGTCTACGATCAGAACT
ACGTTAAAGCGGCGGCCACGCGCGGCTTGTCGCGCTTTACGATTTTACGCCGTCACGTGTTGCATAATGCGCTGCCGCCG
GTCATTCCCCGTCTTGGTCTGCAGTTTTCAACCATGTTAACGCTGGCGATGATTACCGAAATGGTTTTCAGCTGGCCAGG
GCTGGGACGATGGTTAATTCACGCCATTCGTCAGCAGGACTATGCCGCTATTTCCGCTGGCGTGATGGTCATTGGGTCGC
TGGTTATTGTGGTCAATGTGATTTCCGATATTTTGGGTGCTATGGCTAACCCTCTGAAACATAAGGAATGGTATGCCTTA
CGATAA

Upstream 100 bases:

>100_bases
AGGCTTACCGCTACGATATTAAAGGACTGGTGTTAAGCCCGTTCGGCAATGCGTCTTTTGCCGGCGTCTCCCGCGAAAAA
CACGAAGAGGTGAAAAAACC

Downstream 100 bases:

>100_bases
GAAGCAATAAAAATATCATTAAATCAAAAAGTTATGCTTTTATTTTTGTGATAAGTTCGTTTTTTAGTACGTAAATATAT
ACATATTGTTTTCTATTTTC

Product: peptide transport system permease SapB

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MIIFTLRRLLLLLVTLFFLTFIGFSLSYFTPHAPLQGASLWNAWVFWFNGLLHWDFGVSSINGQLISEQLKEVFPATMEL
CILAFGFALMVGIPVGMLAGVTRSKWPDRFISALALLGFSIPVFWLALLLTLFFSLTLGWLPVSGRFDLLYEVKPVTGFA
IIDAWISDSPWRDEMVMSAIRHMVLPVLTLSVAPTTEVIRLMRISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPP
VIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLIHAIRQQDYAAISAGVMVIGSLVIVVNVISDILGAMANPLKHKEWYAL
R

Sequences:

>Translated_321_residues
MIIFTLRRLLLLLVTLFFLTFIGFSLSYFTPHAPLQGASLWNAWVFWFNGLLHWDFGVSSINGQLISEQLKEVFPATMEL
CILAFGFALMVGIPVGMLAGVTRSKWPDRFISALALLGFSIPVFWLALLLTLFFSLTLGWLPVSGRFDLLYEVKPVTGFA
IIDAWISDSPWRDEMVMSAIRHMVLPVLTLSVAPTTEVIRLMRISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPP
VIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLIHAIRQQDYAAISAGVMVIGSLVIVVNVISDILGAMANPLKHKEWYAL
R
>Mature_321_residues
MIIFTLRRLLLLLVTLFFLTFIGFSLSYFTPHAPLQGASLWNAWVFWFNGLLHWDFGVSSINGQLISEQLKEVFPATMEL
CILAFGFALMVGIPVGMLAGVTRSKWPDRFISALALLGFSIPVFWLALLLTLFFSLTLGWLPVSGRFDLLYEVKPVTGFA
IIDAWISDSPWRDEMVMSAIRHMVLPVLTLSVAPTTEVIRLMRISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPP
VIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLIHAIRQQDYAAISAGVMVIGSLVIVVNVISDILGAMANPLKHKEWYAL
R

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4168

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787550, Length=321, Percent_Identity=91.9003115264798, Blast_Score=585, Evalue=1e-168,
Organism=Escherichia coli, GI1789965, Length=344, Percent_Identity=35.1744186046512, Blast_Score=209, Evalue=1e-55,
Organism=Escherichia coli, GI1787053, Length=337, Percent_Identity=28.486646884273, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1787761, Length=246, Percent_Identity=36.1788617886179, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789888, Length=275, Percent_Identity=30.9090909090909, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1787497, Length=332, Percent_Identity=28.0120481927711, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788504, Length=261, Percent_Identity=26.4367816091954, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36112; Mature: 36112

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIFTLRRLLLLLVTLFFLTFIGFSLSYFTPHAPLQGASLWNAWVFWFNGLLHWDFGVSS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHCCCCHHH
INGQLISEQLKEVFPATMELCILAFGFALMVGIPVGMLAGVTRSKWPDRFISALALLGFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHH
IPVFWLALLLTLFFSLTLGWLPVSGRFDLLYEVKPVTGFAIIDAWISDSPWRDEMVMSAI
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHH
RHMVLPVLTLSVAPTTEVIRLMRISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCH
VIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLIHAIRQQDYAAISAGVMVIGSLVIVVNV
HHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISDILGAMANPLKHKEWYALR
HHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MIIFTLRRLLLLLVTLFFLTFIGFSLSYFTPHAPLQGASLWNAWVFWFNGLLHWDFGVSS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHCCCCHHH
INGQLISEQLKEVFPATMELCILAFGFALMVGIPVGMLAGVTRSKWPDRFISALALLGFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHH
IPVFWLALLLTLFFSLTLGWLPVSGRFDLLYEVKPVTGFAIIDAWISDSPWRDEMVMSAI
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHH
RHMVLPVLTLSVAPTTEVIRLMRISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCH
VIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLIHAIRQQDYAAISAGVMVIGSLVIVVNV
HHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISDILGAMANPLKHKEWYALR
HHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]