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The map label for this gene is sseB

Identifier: 29141727

GI number: 29141727

Start: 1338340

End: 1338930

Strand: Direct

Name: sseB

Synonym: t1266

Alternate gene names: 29141727

Gene position: 1338340-1338930 (Clockwise)

Preceding gene: 29141726

Following gene: 29141728

Centisome position: 27.93

GC content: 43.15

Gene sequence:

>591_bases
ATGTCTTCAGGAAACATCTTATGGGGAAGTCAAAACCCTATTGTGTTTAAAAATAGCTTCGGCGTCAGCAACGCTGATAC
CGGGAGCCAGGATGACTTATCCCAGCAAAATCCGTTTGCCGAAGGGTATGGTGTTTTGCTTATTCTCCTTATGGTTATTC
AGGCTATCGCAAATAATAAATTTATTGAAGTCCAGAAGAACGCTGAACGTGCCAGAAATACCCAGGAAAAGTCAAATGAG
ATGGATGAGGTGATTGCTAAAGCAGCCAAAGGGGATGCTAAAACCAAAGAGGAGGTGCCTGAGGATGTAATTAAATACAT
GCGTGATAATGGTATTCTCATCGATGGTATGACCATTGATGATTATATGGCTAAATATGGCGATCATGGGAAGCTGGATA
AAGGTGGCCTACAGGCGATCAAAGCGGCTTTGGATAATGACGCCAACCGGAATACCGATCTTATGAGTCAAGGGCAGATA
ACAATTCAAAAAATGTCTCAGGAGCTTAACGCTGTCCTTACCCAACTGACGGGGCTTATCAGTAAGTGGGGGGAAATTTC
CAGTATGATAGCGCAGAAAACGTATTCATGA

Upstream 100 bases:

>100_bases
AATAGTAAGTTTGTTTAAACAACTTGAAGTACGACTGAAACAACTTAATGCTCAAGCCCCGGTGGAGATACCGTCAGGAA
AAACAAAAAGGTAAAGCATA

Downstream 100 bases:

>100_bases
AAAAAGACCCGACCCTACAACAGGCACATGACACGATGCGATTTTTCCGGCGTGGCGGCTCGCTGCGTATGTTGTTGGAT
GACGATGTTACACAGCCGCT

Product: pathogenicity island effector protein

Products: NA

Alternate protein names: Secretion system effector B

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MSSGNILWGSQNPIVFKNSFGVSNADTGSQDDLSQQNPFAEGYGVLLILLMVIQAIANNKFIEVQKNAERARNTQEKSNE
MDEVIAKAAKGDAKTKEEVPEDVIKYMRDNGILIDGMTIDDYMAKYGDHGKLDKGGLQAIKAALDNDANRNTDLMSQGQI
TIQKMSQELNAVLTQLTGLISKWGEISSMIAQKTYS

Sequences:

>Translated_196_residues
MSSGNILWGSQNPIVFKNSFGVSNADTGSQDDLSQQNPFAEGYGVLLILLMVIQAIANNKFIEVQKNAERARNTQEKSNE
MDEVIAKAAKGDAKTKEEVPEDVIKYMRDNGILIDGMTIDDYMAKYGDHGKLDKGGLQAIKAALDNDANRNTDLMSQGQI
TIQKMSQELNAVLTQLTGLISKWGEISSMIAQKTYS
>Mature_195_residues
SSGNILWGSQNPIVFKNSFGVSNADTGSQDDLSQQNPFAEGYGVLLILLMVIQAIANNKFIEVQKNAERARNTQEKSNEM
DEVIAKAAKGDAKTKEEVPEDVIKYMRDNGILIDGMTIDDYMAKYGDHGKLDKGGLQAIKAALDNDANRNTDLMSQGQIT
IQKMSQELNAVLTQLTGLISKWGEISSMIAQKTYS

Specific function: Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. May act as a translocator that mediates translocation of SPI-2 TTSS effector proteins from intraphagosomal bacterial cells into the host cells. SseB i

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Cell surface. Note=Secreted via type III secretion system 2 (SPI-2 TTSS). After secretion, localizes mainly on the surface of the bacterial cell

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the espA/sseB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SSEB_SALTY (Q7BVH7)

Other databases:

- EMBL:   AJ224892
- EMBL:   AF020808
- EMBL:   AE006468
- RefSeq:   NP_460363.1
- IntAct:   Q7BVH7
- PRIDE:   Q7BVH7
- GeneID:   1252916
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM1398
- HOGENOM:   HBG679508
- OMA:   IQAIAND
- ProtClustDB:   PRK15364
- BioCyc:   STYP99287:STM1398-MONOMER
- GO:   GO:0009405
- InterPro:   IPR005095

Pfam domain/function: PF03433 EspA

EC number: NA

Molecular weight: Translated: 21496; Mature: 21364

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSGNILWGSQNPIVFKNSFGVSNADTGSQDDLSQQNPFAEGYGVLLILLMVIQAIANNK
CCCCCEEECCCCCEEEECCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCC
FIEVQKNAERARNTQEKSNEMDEVIAKAAKGDAKTKEEVPEDVIKYMRDNGILIDGMTID
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEECCCHH
DYMAKYGDHGKLDKGGLQAIKAALDNDANRNTDLMSQGQITIQKMSQELNAVLTQLTGLI
HHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHH
SKWGEISSMIAQKTYS
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSGNILWGSQNPIVFKNSFGVSNADTGSQDDLSQQNPFAEGYGVLLILLMVIQAIANNK
CCCCEEECCCCCEEEECCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCC
FIEVQKNAERARNTQEKSNEMDEVIAKAAKGDAKTKEEVPEDVIKYMRDNGILIDGMTID
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEECCCHH
DYMAKYGDHGKLDKGGLQAIKAALDNDANRNTDLMSQGQITIQKMSQELNAVLTQLTGLI
HHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHH
SKWGEISSMIAQKTYS
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9786193; 9786194; 11677609