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The map label for this gene is msrB [H]

Identifier: 29141636

GI number: 29141636

Start: 1237879

End: 1238322

Strand: Direct

Name: msrB [H]

Synonym: t1170

Alternate gene names: 29141636

Gene position: 1237879-1238322 (Clockwise)

Preceding gene: 29141634

Following gene: 29141637

Centisome position: 25.83

GC content: 51.13

Gene sequence:

>444_bases
GTGAGCACGTTTAAAGTGAGATGTGAGCAAATGGCTAACCAACCTTCAGCAGAAGAACTCAAGAAAAAATTGTCCGAAAT
GCAATTCTATGTGACGCAGGATCGTGGCACAGAACCGCCATTTACCGGACGCCTGCTACATAATAAACGCGATGGGGTTT
ATCACTGCCTGGTCTGTGATACGCCGCTTTTTCACTCCCACACCAAATACGATTCAGGCTGCGGCTGGCCTAGCTTTTAC
CAGCCTGTCAGCGAAGAGGCGATTCGTTACATAGACGATTTTTCTCATGGCATGCAGCGTGTCGAAATTCGTTGCGGTAA
CTGCGATGCGCATCTCGGACACGTTTTCCCGGACGGGCCGCAGCCAACCGGTGAGCGCTATTGCGTTAACTCGGCCTCGC
TGGCCTTTTCTGACGAGAAAAACGGCGATCAACTGAAAGGCTGA

Upstream 100 bases:

>100_bases
ACATCAGTCACGATTCGTGAGCCGCCATTTCGCAATGATCAAGTTTAGAACAAAAGTTGGTACTGAGGTGCTAATGTTTT
GTTAGAATCGGTCAGGCAAT

Downstream 100 bases:

>100_bases
AAAAACGATTCAGCAAATTATTCCACAGGAGCGGACACATCATGAATCTTGATGAGATCATTAACAGCATGACGCCGGAA
GTGTATCAACGTTTATCCAC

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MSTFKVRCEQMANQPSAEELKKKLSEMQFYVTQDRGTEPPFTGRLLHNKRDGVYHCLVCDTPLFHSHTKYDSGCGWPSFY
QPVSEEAIRYIDDFSHGMQRVEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLAFSDEKNGDQLKG

Sequences:

>Translated_147_residues
MSTFKVRCEQMANQPSAEELKKKLSEMQFYVTQDRGTEPPFTGRLLHNKRDGVYHCLVCDTPLFHSHTKYDSGCGWPSFY
QPVSEEAIRYIDDFSHGMQRVEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLAFSDEKNGDQLKG
>Mature_146_residues
STFKVRCEQMANQPSAEELKKKLSEMQFYVTQDRGTEPPFTGRLLHNKRDGVYHCLVCDTPLFHSHTKYDSGCGWPSFYQ
PVSEEAIRYIDDFSHGMQRVEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLAFSDEKNGDQLKG

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=132, Percent_Identity=53.7878787878788, Blast_Score=165, Evalue=1e-41,
Organism=Homo sapiens, GI301336162, Length=132, Percent_Identity=53.7878787878788, Blast_Score=165, Evalue=1e-41,
Organism=Homo sapiens, GI73089054, Length=132, Percent_Identity=53.7878787878788, Blast_Score=165, Evalue=1e-41,
Organism=Homo sapiens, GI37620216, Length=132, Percent_Identity=53.7878787878788, Blast_Score=165, Evalue=2e-41,
Organism=Homo sapiens, GI117606353, Length=130, Percent_Identity=51.5384615384615, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI1788077, Length=137, Percent_Identity=85.4014598540146, Blast_Score=260, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17553450, Length=134, Percent_Identity=46.2686567164179, Blast_Score=121, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI115532676, Length=134, Percent_Identity=46.2686567164179, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319816, Length=145, Percent_Identity=40.6896551724138, Blast_Score=114, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24645799, Length=120, Percent_Identity=51.6666666666667, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI45553335, Length=122, Percent_Identity=50.8196721311475, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21356369, Length=122, Percent_Identity=50.8196721311475, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI221378664, Length=120, Percent_Identity=51.6666666666667, Blast_Score=129, Evalue=6e-31,
Organism=Drosophila melanogaster, GI221378662, Length=127, Percent_Identity=48.0314960629921, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24645801, Length=133, Percent_Identity=47.3684210526316, Blast_Score=126, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24645804, Length=133, Percent_Identity=46.6165413533835, Blast_Score=126, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 16682; Mature: 16551

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTFKVRCEQMANQPSAEELKKKLSEMQFYVTQDRGTEPPFTGRLLHNKRDGVYHCLVCD
CCHHHHHHHHHCCCCCHHHHHHHHHHHHEEEECCCCCCCCCCCHHHCCCCCCEEEEEEEC
TPLFHSHTKYDSGCGWPSFYQPVSEEAIRYIDDFSHGMQRVEIRCGNCDAHLGHVFPDGP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCC
QPTGERYCVNSASLAFSDEKNGDQLKG
CCCCCEEECCCCCEEECCCCCCCCCCC
>Mature Secondary Structure 
STFKVRCEQMANQPSAEELKKKLSEMQFYVTQDRGTEPPFTGRLLHNKRDGVYHCLVCD
CHHHHHHHHHCCCCCHHHHHHHHHHHHEEEECCCCCCCCCCCHHHCCCCCCEEEEEEEC
TPLFHSHTKYDSGCGWPSFYQPVSEEAIRYIDDFSHGMQRVEIRCGNCDAHLGHVFPDGP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCC
QPTGERYCVNSASLAFSDEKNGDQLKG
CCCCCEEECCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA