BacMap

Definition	Salmonella enterica subsp. enterica serovar Typhi str. Ty2 chromosome, complete genome.
Accession	NC_004631
Length	4,791,961

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The map label for this gene is yeaE [H]

Identifier: 29141634

GI number: 29141634

Start: 1234403

End: 1235260

Strand: Direct

Name: yeaE [H]

Synonym: t1167

Alternate gene names: 29141634

Gene position: 1234403-1235260 (Clockwise)

Preceding gene: 29141633

Following gene: 29141636

Centisome position: 25.76

GC content: 55.24

Gene sequence:

>858_bases
ATGAAATCAGTGAAAAACGTAACGTTTTGCGGGCAGGTGACGCTTCCTGCCATCGGACAGGGAACATGGTATATGGGCGA
GCGCGCGGATCAACGTCAGCGCGAGGTTTCGGCGCTGCGCGCGGGGCTGGATTTGGGGTTACGCCTTATTGATACGGCGG
AAATGTATGCCGACGGCGGGGCGGAAAAGGTCGTGGGCGAGGCGTTAGCAGGGCGACGCGATGAGGCATTTCTAGTGTCA
AAAGTGTACCCGTGGAACGCTGGCGGCCAGAAGATAGTTGCCGCCTGTGAGGAAAGCCTGCGTCGTCTGAAAACAGATTA
TCTCGATCTCTATCTATTGCACTGGGCCGGAGGCTTTTCATTCGAAGAGACCGTTGAAGGTATGGAGCGGCTAATCGCGC
AGGGAAAAATTCGCCGTTGGGGAGTCTCTAATCTTGATTATGACGATATGCAGGCGCTGTGGCGCATCCCTGGGGGACAG
CAATGCGCGACAAATCAGGTGCTCTATCATCTGGCGTCACGCGGTATTGAGTATGATTTATTGCCGTGGTGTCAACAACA
GCGAATGCCAGTGATGGCCTATAGCCCGCTGGCGCAGGCTGGCCGGTTACGTAGCGGTTTACTGAATCATCCGGTGGTGA
ATGAAATTGCGCAAGCGCATAACGCAACGGCGGCGCAAATCTTACTGACGTGGGTGATTGCGCATCCGGGCGTGATGGCG
ATCCCGAAAGCCGGAAGTACAGAACACGTGAAGCAAAATGCGGCGGCGCTTGAGATTACCTTGTCAGCAAACGAACTTGC
CTTACTGGACAACGCCTGGCCTGCGCCAAAAGGGAAAACCGCGTTGGATATGGTGTGA

Upstream 100 bases:

>100_bases
TGACAAGAAAATCGCCCCCCTTGCGCGGTATGATGCCGGACATTACCGTAGGGTCTAAGAGTCCTGTATTGTTTTACCGT
CGAGTGAAATTGAAAAGGAA

Downstream 100 bases:

>100_bases
CGCCGGATAAAATGTGTAAGTGCCGCCATCCGGCAGGTCATGCCTGATGGCGGCTGGCGCCTTCCAGAGCCTATAGCAAC
GCCGTTATCCATTCACTTTT

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MKSVKNVTFCGQVTLPAIGQGTWYMGERADQRQREVSALRAGLDLGLRLIDTAEMYADGGAEKVVGEALAGRRDEAFLVS
KVYPWNAGGQKIVAACEESLRRLKTDYLDLYLLHWAGGFSFEETVEGMERLIAQGKIRRWGVSNLDYDDMQALWRIPGGQ
QCATNQVLYHLASRGIEYDLLPWCQQQRMPVMAYSPLAQAGRLRSGLLNHPVVNEIAQAHNATAAQILLTWVIAHPGVMA
IPKAGSTEHVKQNAAALEITLSANELALLDNAWPAPKGKTALDMV

Sequences:

>Translated_285_residues
MKSVKNVTFCGQVTLPAIGQGTWYMGERADQRQREVSALRAGLDLGLRLIDTAEMYADGGAEKVVGEALAGRRDEAFLVS
KVYPWNAGGQKIVAACEESLRRLKTDYLDLYLLHWAGGFSFEETVEGMERLIAQGKIRRWGVSNLDYDDMQALWRIPGGQ
QCATNQVLYHLASRGIEYDLLPWCQQQRMPVMAYSPLAQAGRLRSGLLNHPVVNEIAQAHNATAAQILLTWVIAHPGVMA
IPKAGSTEHVKQNAAALEITLSANELALLDNAWPAPKGKTALDMV
>Mature_285_residues
MKSVKNVTFCGQVTLPAIGQGTWYMGERADQRQREVSALRAGLDLGLRLIDTAEMYADGGAEKVVGEALAGRRDEAFLVS
KVYPWNAGGQKIVAACEESLRRLKTDYLDLYLLHWAGGFSFEETVEGMERLIAQGKIRRWGVSNLDYDDMQALWRIPGGQ
QCATNQVLYHLASRGIEYDLLPWCQQQRMPVMAYSPLAQAGRLRSGLLNHPVVNEIAQAHNATAAQILLTWVIAHPGVMA
IPKAGSTEHVKQNAAALEITLSANELALLDNAWPAPKGKTALDMV

Specific function: Unknown

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI223468663, Length=298, Percent_Identity=30.2013422818792, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI291291012, Length=265, Percent_Identity=30.5660377358491, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI93277124, Length=299, Percent_Identity=26.4214046822742, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI24497577, Length=299, Percent_Identity=28.7625418060201, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI5174391, Length=299, Percent_Identity=28.7625418060201, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI5174695, Length=287, Percent_Identity=27.1777003484321, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI300116273, Length=274, Percent_Identity=27.7372262773723, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI310109922, Length=273, Percent_Identity=27.8388278388278, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI4502049, Length=290, Percent_Identity=28.9655172413793, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI24497585, Length=290, Percent_Identity=26.8965517241379, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI310109920, Length=290, Percent_Identity=25.8620689655172, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI300116271, Length=266, Percent_Identity=26.6917293233083, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI45446745, Length=290, Percent_Identity=25.5172413793103, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4503285, Length=290, Percent_Identity=25.5172413793103, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI24497583, Length=291, Percent_Identity=26.8041237113402, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI5453543, Length=290, Percent_Identity=25.5172413793103, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI1788081, Length=281, Percent_Identity=77.9359430604982, Blast_Score=467, Evalue=1e-133,
Organism=Escherichia coli, GI1786400, Length=261, Percent_Identity=29.8850574712644, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI87081735, Length=306, Percent_Identity=27.4509803921569, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI87082198, Length=258, Percent_Identity=29.0697674418605, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1788070, Length=313, Percent_Identity=27.1565495207668, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789375, Length=334, Percent_Identity=25.748502994012, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789199, Length=338, Percent_Identity=27.2189349112426, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787674, Length=257, Percent_Identity=24.5136186770428, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI48994888, Length=268, Percent_Identity=27.2388059701493, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17564128, Length=307, Percent_Identity=29.3159609120521, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17552492, Length=270, Percent_Identity=30.7407407407407, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17561298, Length=279, Percent_Identity=30.1075268817204, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI71998625, Length=279, Percent_Identity=29.7491039426523, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17537077, Length=301, Percent_Identity=28.5714285714286, Blast_Score=97, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17566692, Length=297, Percent_Identity=27.2727272727273, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17537075, Length=301, Percent_Identity=28.9036544850498, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17561300, Length=257, Percent_Identity=28.0155642023346, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17538386, Length=277, Percent_Identity=29.2418772563177, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17550248, Length=295, Percent_Identity=24.7457627118644, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17537079, Length=308, Percent_Identity=22.0779220779221, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320576, Length=303, Percent_Identity=26.7326732673267, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320079, Length=265, Percent_Identity=28.3018867924528, Blast_Score=89, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6322556, Length=270, Percent_Identity=23.7037037037037, Blast_Score=75, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6323998, Length=310, Percent_Identity=23.5483870967742, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644950, Length=313, Percent_Identity=33.2268370607029, Blast_Score=133, Evalue=1e-31,
Organism=Drosophila melanogaster, GI221378297, Length=333, Percent_Identity=31.5315315315315, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24663317, Length=303, Percent_Identity=25.7425742574257, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI45553081, Length=300, Percent_Identity=26, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24662789, Length=287, Percent_Identity=27.5261324041812, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24657054, Length=292, Percent_Identity=25.6849315068493, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281366140, Length=256, Percent_Identity=26.5625, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI20129731, Length=282, Percent_Identity=26.9503546099291, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21356425, Length=263, Percent_Identity=22.0532319391635, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24662781, Length=292, Percent_Identity=26.027397260274, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24662785, Length=280, Percent_Identity=25.3571428571429, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 31328; Mature: 31328

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSVKNVTFCGQVTLPAIGQGTWYMGERADQRQREVSALRAGLDLGLRLIDTAEMYADGG
CCCCCCEEEECCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCC
AEKVVGEALAGRRDEAFLVSKVYPWNAGGQKIVAACEESLRRLKTDYLDLYLLHWAGGFS
HHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FEETVEGMERLIAQGKIRRWGVSNLDYDDMQALWRIPGGQQCATNQVLYHLASRGIEYDL
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCC
LPWCQQQRMPVMAYSPLAQAGRLRSGLLNHPVVNEIAQAHNATAAQILLTWVIAHPGVMA
CCHHHHCCCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCEEE
IPKAGSTEHVKQNAAALEITLSANELALLDNAWPAPKGKTALDMV
ECCCCCHHHHHCCCEEEEEEECCCCEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKSVKNVTFCGQVTLPAIGQGTWYMGERADQRQREVSALRAGLDLGLRLIDTAEMYADGG
CCCCCCEEEECCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCC
AEKVVGEALAGRRDEAFLVSKVYPWNAGGQKIVAACEESLRRLKTDYLDLYLLHWAGGFS
HHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FEETVEGMERLIAQGKIRRWGVSNLDYDDMQALWRIPGGQQCATNQVLYHLASRGIEYDL
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCC
LPWCQQQRMPVMAYSPLAQAGRLRSGLLNHPVVNEIAQAHNATAAQILLTWVIAHPGVMA
CCHHHHCCCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCEEE
IPKAGSTEHVKQNAAALEITLSANELALLDNAWPAPKGKTALDMV
ECCCCCHHHHHCCCEEEEEEECCCCEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]