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The map label for this gene is ptxA [H]

Identifier: 29141580

GI number: 29141580

Start: 1192875

End: 1193603

Strand: Direct

Name: ptxA [H]

Synonym: t1108

Alternate gene names: 29141580

Gene position: 1192875-1193603 (Clockwise)

Preceding gene: 29141579

Following gene: 29141581

Centisome position: 24.89

GC content: 38.68

Gene sequence:

>729_bases
ATGAAAAAGTTAATATTCTTAACCTTATCTATAGTTAGCTTTAATAACTATGCTGTAGATTTTGTGTATCGTGTGGACTC
AACCCCGCCGGACGTTATTTTTCGCGATGGGTTTTCACTACTTGGGTATAACCGTAACTTTCAGCAATTTATTAGTGGAA
GGTCATGTAGTGGTGGAAGTAGTGACAGTCGCTATATTGCAACAACCTCAAGTGTTAATCAAACATATGCTATAGCCAGA
GCGTACTATTCTCGCTCAACATTCAAAGGTAATTTATACAGATATCAGATTCGTGCAGATAATAATTTCTACAGCTTGCT
CCCATCCATCACCTATCTGGAAACGCAAGGTGGTCACTTTAATGCTTATGAAAAAACGATGATGCGATTGCAAAGAGAGT
ATGTTTCCACATTATCTATTTTACCCGAGAATATTCAAAAGGCCGTGGCGCTAGTTTATGATAGCGCAACCGGTCTAGTA
AAGGATGGTGTAAGCACAATGAATGCCAGTTATTTAGGTTTAAGCACTACGTCTAATCCTGGTGTGATACCTTTTCTTCC
GGAACCGCAGACGTATACCCAACAACGAATTGATGCATTCGGCCCATTAATAAGTTCATGCTTTTCAATAGGTAGCGTAT
GTCATTCACATCGAGGGCAAAGAGCTGACGTATACAACATGTCTTTTTATGATGCAAGACCTGTAATAGAACTTATACTT
TCTAAATAA

Upstream 100 bases:

>100_bases
CCGCTTTTTGTTAATACCTTTTCAGCAAATGCTCTTGTGGGACTATCATCGTGCAGTGCGACACAATGCTTTGGACCCAA
GTAAGAGGGGAGAAGAAATA

Downstream 100 bases:

>100_bases
ATGAAACTTACCTATGTTGCCTATTAAATTAAACAGCCCGTTTATTAGTTGCCTGGTTAATATTGTTTATTAAGTTGGCT
ATCCACTTAAATATAAATGT

Product: toxin subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MKKLIFLTLSIVSFNNYAVDFVYRVDSTPPDVIFRDGFSLLGYNRNFQQFISGRSCSGGSSDSRYIATTSSVNQTYAIAR
AYYSRSTFKGNLYRYQIRADNNFYSLLPSITYLETQGGHFNAYEKTMMRLQREYVSTLSILPENIQKAVALVYDSATGLV
KDGVSTMNASYLGLSTTSNPGVIPFLPEPQTYTQQRIDAFGPLISSCFSIGSVCHSHRGQRADVYNMSFYDARPVIELIL
SK

Sequences:

>Translated_242_residues
MKKLIFLTLSIVSFNNYAVDFVYRVDSTPPDVIFRDGFSLLGYNRNFQQFISGRSCSGGSSDSRYIATTSSVNQTYAIAR
AYYSRSTFKGNLYRYQIRADNNFYSLLPSITYLETQGGHFNAYEKTMMRLQREYVSTLSILPENIQKAVALVYDSATGLV
KDGVSTMNASYLGLSTTSNPGVIPFLPEPQTYTQQRIDAFGPLISSCFSIGSVCHSHRGQRADVYNMSFYDARPVIELIL
SK
>Mature_242_residues
MKKLIFLTLSIVSFNNYAVDFVYRVDSTPPDVIFRDGFSLLGYNRNFQQFISGRSCSGGSSDSRYIATTSSVNQTYAIAR
AYYSRSTFKGNLYRYQIRADNNFYSLLPSITYLETQGGHFNAYEKTMMRLQREYVSTLSILPENIQKAVALVYDSATGLV
KDGVSTMNASYLGLSTTSNPGVIPFLPEPQTYTQQRIDAFGPLISSCFSIGSVCHSHRGQRADVYNMSFYDARPVIELIL
SK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial exotoxin subunit A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003898 [H]

Pfam domain/function: PF02917 Pertussis_S1 [H]

EC number: NA

Molecular weight: Translated: 27179; Mature: 27179

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLIFLTLSIVSFNNYAVDFVYRVDSTPPDVIFRDGFSLLGYNRNFQQFISGRSCSGGS
CCEEEEEEEEEEECCCEEEEEEEEECCCCCCEEEECCCEEECCCCCHHHHHCCCCCCCCC
SDSRYIATTSSVNQTYAIARAYYSRSTFKGNLYRYQIRADNNFYSLLPSITYLETQGGHF
CCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHCCCEEEEECCCCCC
NAYEKTMMRLQREYVSTLSILPENIQKAVALVYDSATGLVKDGVSTMNASYLGLSTTSNP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHCCCEEEEEECCCCC
GVIPFLPEPQTYTQQRIDAFGPLISSCFSIGSVCHSHRGQRADVYNMSFYDARPVIELIL
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHCHHHHHHHHH
SK
CC
>Mature Secondary Structure
MKKLIFLTLSIVSFNNYAVDFVYRVDSTPPDVIFRDGFSLLGYNRNFQQFISGRSCSGGS
CCEEEEEEEEEEECCCEEEEEEEEECCCCCCEEEECCCEEECCCCCHHHHHCCCCCCCCC
SDSRYIATTSSVNQTYAIARAYYSRSTFKGNLYRYQIRADNNFYSLLPSITYLETQGGHF
CCCEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHCCCEEEEECCCCCC
NAYEKTMMRLQREYVSTLSILPENIQKAVALVYDSATGLVKDGVSTMNASYLGLSTTSNP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHCCCEEEEEECCCCC
GVIPFLPEPQTYTQQRIDAFGPLISSCFSIGSVCHSHRGQRADVYNMSFYDARPVIELIL
CEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHCHHHHHHHHH
SK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271; 3584073 [H]