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The map label for this gene is udk [H]

Identifier: 29141252

GI number: 29141252

Start: 837774

End: 838415

Strand: Direct

Name: udk [H]

Synonym: t0750

Alternate gene names: 29141252

Gene position: 837774-838415 (Clockwise)

Preceding gene: 29141250

Following gene: 29141253

Centisome position: 17.48

GC content: 46.88

Gene sequence:

>642_bases
ATGACTGATCAGTCTCATCAGTGCGTCATTATCGGTATCGCTGGCGCATCGGCTTCCGGCAAGAGTCTTATTGCCAGTAC
CCTTTACCGCGAATTGCGTGAACAAGTGGGTGACGAACATATTGGCGTTATTCCCGAAGACAGTTATTACAAAGATCAAA
GCCATCTGTCGATGGAAGAACGCGTAAAAACTAACTATGACCATCCGAATGCGATGGATCACAGCCTGCTATTTCAGCAT
CTTCAGGCGCTCAAGCGCGGTTCGGCGATTGAATTACCGGTATACAGTTATGTTGAGCATACCCGTATGCAGGAAACGGT
TCGCGTAGAACCGAAGAAAGTGATTATTCTTGAAGGTATTCTGTTACTGACCGACGCGCGTTTGCGTGAAGAGATGAACT
TCTCTATTTTTGTCGATACGCCGCTGGATATCTGTTTGATGCGCCGTATCAAACGCGATGTGAACGAGCGTGGTCGCTCA
ATGGATTCGGTGATGGCGCAATATCAGAAAACGGTGCGTCCGATGTTCCTGCAATTTATTGAGCCTTCCAAACAATATGC
GGATATTATCGTGCCGCGCGGCGGTAAAAACCGCATCGCTATTGATATTCTGAAAGCGAAAATCAGCCAGTTCTTTGAAT
AA

Upstream 100 bases:

>100_bases
CGCCGGACTGGTATCGCGCTGCTGAAATCCCTATAATTGCCGCGTTTGGCGTTTCGGCGCCCCCCTTCTTTACATCCAGG
TTAATCAGGTCGCTAAATTT

Downstream 100 bases:

>100_bases
ATCTGGCGAATTGTGTACCGTTCAGTGATAACCTGGTTAGCCCTTGATGTGCTTGATTTAAGGGCTTGATGCGCGAAAGG
AGAAAGTGCCATGCGTTTAT

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase [H]

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDSYYKDQSHLSMEERVKTNYDHPNAMDHSLLFQH
LQALKRGSAIELPVYSYVEHTRMQETVRVEPKKVIILEGILLLTDARLREEMNFSIFVDTPLDICLMRRIKRDVNERGRS
MDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE

Sequences:

>Translated_213_residues
MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDSYYKDQSHLSMEERVKTNYDHPNAMDHSLLFQH
LQALKRGSAIELPVYSYVEHTRMQETVRVEPKKVIILEGILLLTDARLREEMNFSIFVDTPLDICLMRRIKRDVNERGRS
MDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
>Mature_212_residues
TDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDSYYKDQSHLSMEERVKTNYDHPNAMDHSLLFQHL
QALKRGSAIELPVYSYVEHTRMQETVRVEPKKVIILEGILLLTDARLREEMNFSIFVDTPLDICLMRRIKRDVNERGRSM
DSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family [H]

Homologues:

Organism=Homo sapiens, GI18699734, Length=203, Percent_Identity=36.4532019704434, Blast_Score=158, Evalue=3e-39,
Organism=Homo sapiens, GI57863312, Length=203, Percent_Identity=38.9162561576355, Blast_Score=158, Evalue=4e-39,
Organism=Homo sapiens, GI301129207, Length=203, Percent_Identity=38.9162561576355, Blast_Score=158, Evalue=4e-39,
Organism=Homo sapiens, GI13899253, Length=211, Percent_Identity=35.5450236966825, Blast_Score=146, Evalue=1e-35,
Organism=Homo sapiens, GI209863022, Length=159, Percent_Identity=32.7044025157233, Blast_Score=94, Evalue=7e-20,
Organism=Escherichia coli, GI87082034, Length=213, Percent_Identity=95.7746478873239, Blast_Score=424, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI17539894, Length=207, Percent_Identity=38.1642512077295, Blast_Score=152, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17539892, Length=207, Percent_Identity=38.1642512077295, Blast_Score=152, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI71981181, Length=216, Percent_Identity=34.2592592592593, Blast_Score=129, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6324339, Length=177, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI221458995, Length=221, Percent_Identity=36.1990950226244, Blast_Score=155, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24649624, Length=218, Percent_Identity=36.2385321100917, Blast_Score=154, Evalue=6e-38,
Organism=Drosophila melanogaster, GI45550449, Length=197, Percent_Identity=38.5786802030457, Blast_Score=146, Evalue=9e-36,
Organism=Drosophila melanogaster, GI28573516, Length=197, Percent_Identity=38.5786802030457, Blast_Score=146, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28573514, Length=197, Percent_Identity=38.5786802030457, Blast_Score=146, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28573512, Length=197, Percent_Identity=38.5786802030457, Blast_Score=146, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006083
- InterPro:   IPR000764 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.48 [H]

Molecular weight: Translated: 24499; Mature: 24367

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDSYYKDQSHLSMEE
CCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCHHH
RVKTNYDHPNAMDHSLLFQHLQALKRGSAIELPVYSYVEHTRMQETVRVEPKKVIILEGI
HHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHH
LLLTDARLREEMNFSIFVDTPLDICLMRRIKRDVNERGRSMDSVMAQYQKTVRPMFLQFI
HHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
EPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
CCCHHHHEEEECCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDSYYKDQSHLSMEE
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCHHH
RVKTNYDHPNAMDHSLLFQHLQALKRGSAIELPVYSYVEHTRMQETVRVEPKKVIILEGI
HHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEHHH
LLLTDARLREEMNFSIFVDTPLDICLMRRIKRDVNERGRSMDSVMAQYQKTVRPMFLQFI
HHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
EPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
CCCHHHHEEEECCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]