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The map label for this gene is gbpR [H]

Identifier: 29141182

GI number: 29141182

Start: 760564

End: 761472

Strand: Reverse

Name: gbpR [H]

Synonym: t0675

Alternate gene names: 29141182

Gene position: 761472-760564 (Counterclockwise)

Preceding gene: 29141189

Following gene: 29141181

Centisome position: 15.89

GC content: 54.68

Gene sequence:

>909_bases
ATGGCGAACTGGGCGCAGAAATTGAAATTACATCACCTGCAAACGCTGGTTGCGCTGGGCGAACAGGGCAACCTGACGCA
CGTCGCCCGGATGATGAATATCTCCCAGCCGGCGCTATCGAAGTGGCTATCTCAACTCGAAGATGAGATAGGCATCACGC
TTTTTGAGCGCCACAGTAAAGGACTACGCCCCTCGGAAGGCGGTAAATTACTGCTCCAGCACGCCCAGCGCCTAATTAAC
GATCTGGAGCGTTCACAGTATGAAATCGCCCGTTTCAAGCAGGGCGGCCTGGTTGGCAGCCTGAAGATCGGCTGTTCGCC
CGTGGCGACTGACTGCGTATCACAGGCGATTCTGAGCCTGCTTAACGAAATGCCGACGCTGCATCTGAATATTGAAGAGA
AGGTAATGACGCCGCTGCTGCACGATTTGCTTGCCGGTCAGGTGGATGTGGTGGTAGGGCGTGTCGGCGGCCGCGCCCTG
CAACTGCCGCTTAATTATCAGGTACTTTATACCGAGCCGGTCTGCTTTGTGGCGCGTCCGCACCATCCGCTGGCCGCGCG
AGCGCAGATCGCCTGGAGCGATCTGGCACACTGGCGGTGGATAGTCTGGCCAACCGGCACCCCTATTCGCATCAGTATTG
ATAACGCCCTCGTCGATAATGGCGTCATGCTCCCGGAAAACACCATTGAATCGGCGTCAATGAACGTCAGCACCAATTTG
CTGCAAAGCAGCGATATGATCTCTATTCTTTCTTTACGGCTGGCGCAACGCTATGCCAGCCAGGGGCAACTGGCGATTTT
AAACTTGCCAAAAATTGAGCAAAAAGGCAGCGTAGGGATGTTCTGGCGTAAGAATGAGACGCCGTCTTTGGCCCTGAGTC
GCTTTTTGTATTTTTTAGCCCAGGTTTAA

Upstream 100 bases:

>100_bases
AGATGTTGTTTTTATGTTTGCTATGTTACGAGTTTGTAGAGTGAGCGATAAAATGTACAATGGCTTTTCAGGCAGAGACA
TAACCTGGAGGTTATAGCGA

Downstream 100 bases:

>100_bases
CGCCGCCGACCAGGGGCATTGCCCGATGTTCCTGCTGTCTATACCCACTATGCTAAGAATTCATGATGTGATCGGTAGCA
CGTTTTAACGTTTAATTGTA

Product: transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MANWAQKLKLHHLQTLVALGEQGNLTHVARMMNISQPALSKWLSQLEDEIGITLFERHSKGLRPSEGGKLLLQHAQRLIN
DLERSQYEIARFKQGGLVGSLKIGCSPVATDCVSQAILSLLNEMPTLHLNIEEKVMTPLLHDLLAGQVDVVVGRVGGRAL
QLPLNYQVLYTEPVCFVARPHHPLAARAQIAWSDLAHWRWIVWPTGTPIRISIDNALVDNGVMLPENTIESASMNVSTNL
LQSSDMISILSLRLAQRYASQGQLAILNLPKIEQKGSVGMFWRKNETPSLALSRFLYFLAQV

Sequences:

>Translated_302_residues
MANWAQKLKLHHLQTLVALGEQGNLTHVARMMNISQPALSKWLSQLEDEIGITLFERHSKGLRPSEGGKLLLQHAQRLIN
DLERSQYEIARFKQGGLVGSLKIGCSPVATDCVSQAILSLLNEMPTLHLNIEEKVMTPLLHDLLAGQVDVVVGRVGGRAL
QLPLNYQVLYTEPVCFVARPHHPLAARAQIAWSDLAHWRWIVWPTGTPIRISIDNALVDNGVMLPENTIESASMNVSTNL
LQSSDMISILSLRLAQRYASQGQLAILNLPKIEQKGSVGMFWRKNETPSLALSRFLYFLAQV
>Mature_301_residues
ANWAQKLKLHHLQTLVALGEQGNLTHVARMMNISQPALSKWLSQLEDEIGITLFERHSKGLRPSEGGKLLLQHAQRLIND
LERSQYEIARFKQGGLVGSLKIGCSPVATDCVSQAILSLLNEMPTLHLNIEEKVMTPLLHDLLAGQVDVVVGRVGGRALQ
LPLNYQVLYTEPVCFVARPHHPLAARAQIAWSDLAHWRWIVWPTGTPIRISIDNALVDNGVMLPENTIESASMNVSTNLL
QSSDMISILSLRLAQRYASQGQLAILNLPKIEQKGSVGMFWRKNETPSLALSRFLYFLAQV

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081904, Length=247, Percent_Identity=30.7692307692308, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1787601, Length=248, Percent_Identity=26.2096774193548, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI157672245, Length=291, Percent_Identity=25.7731958762887, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI145693105, Length=296, Percent_Identity=24.6621621621622, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790399, Length=281, Percent_Identity=24.1992882562278, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787879, Length=199, Percent_Identity=26.6331658291457, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789639, Length=150, Percent_Identity=28, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1789204, Length=265, Percent_Identity=26.4150943396226, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790262, Length=235, Percent_Identity=27.6595744680851, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788297, Length=147, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789506, Length=284, Percent_Identity=20.7746478873239, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33628; Mature: 33496

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANWAQKLKLHHLQTLVALGEQGNLTHVARMMNISQPALSKWLSQLEDEIGITLFERHSK
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEECCCC
GLRPSEGGKLLLQHAQRLINDLERSQYEIARFKQGGLVGSLKIGCSPVATDCVSQAILSL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHH
LNEMPTLHLNIEEKVMTPLLHDLLAGQVDVVVGRVGGRALQLPLNYQVLYTEPVCFVARP
HHCCCEEEECHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCEEEEEECCEEEEECC
HHPLAARAQIAWSDLAHWRWIVWPTGTPIRISIDNALVDNGVMLPENTIESASMNVSTNL
CCCCHHHHHHHHHHHCCEEEEEECCCCEEEEEECCEEECCCEECCCCCCCCCCCCHHHHH
LQSSDMISILSLRLAQRYASQGQLAILNLPKIEQKGSVGMFWRKNETPSLALSRFLYFLA
HHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHH
QV
CC
>Mature Secondary Structure 
ANWAQKLKLHHLQTLVALGEQGNLTHVARMMNISQPALSKWLSQLEDEIGITLFERHSK
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEECCCC
GLRPSEGGKLLLQHAQRLINDLERSQYEIARFKQGGLVGSLKIGCSPVATDCVSQAILSL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHH
LNEMPTLHLNIEEKVMTPLLHDLLAGQVDVVVGRVGGRALQLPLNYQVLYTEPVCFVARP
HHCCCEEEECHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCEEEEEECCEEEEECC
HHPLAARAQIAWSDLAHWRWIVWPTGTPIRISIDNALVDNGVMLPENTIESASMNVSTNL
CCCCHHHHHHHHHHHCCEEEEEECCCCEEEEEECCEEECCCEECCCCCCCCCCCCHHHHH
LQSSDMISILSLRLAQRYASQGQLAILNLPKIEQKGSVGMFWRKNETPSLALSRFLYFLA
HHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHH
QV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]