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The map label for this gene is aegA [H]

Identifier: 29140907

GI number: 29140907

Start: 453032

End: 454891

Strand: Direct

Name: aegA [H]

Synonym: t0380

Alternate gene names: 29140907

Gene position: 453032-454891 (Clockwise)

Preceding gene: 29140901

Following gene: 29140909

Centisome position: 9.45

GC content: 58.49

Gene sequence:

>1860_bases
ATGAATCGTTTTATTATGGCCAATAGCCAGCAGTGTCTGGGATGCCATGCCTGCGAGGTCGCCTGCGTAATGGCTCACAA
TGATGAGCGACATGTTCTGACGCCACAGCGCTATCAGCCCCGAATTACTGTCATCAAACATCAGCGCCAGCGCAGCGCGG
TTACATGTCACCATTGCGAAGATGCGCCCTGCGCCCGTAGCTGTCCGAACGGCGCGATCGCGCATATTAACGACAGCGTG
CAGGTCAATGCGCAGAAGTGCATCGGCTGTAAGTCCTGCGTCGTCGCCTGCCCATTCGGCACCATGCAGATGGTATTGAC
GCCCGTCGCGCCAAACCAGTTCAAAGCCAGCGCGCATAAATGCGATCTGTGTCAGGGACGTGAACAGGGTCCGGCCTGTG
TGGAAAATTGCCCGGCGGATGCGCTGCAACTGGTCACCGAAGACTCGTTGACCCGTCTGGCTAAAACGCGACGGCTGCGT
ACCGCCCGGCAGGAGATTCGCCCCTGGCATACCGTGGATACACAACACAGTGGGACAGCATGCAGCAAAGTCGAGCGTAT
GCAGGCGACGCCGCCGCGCGGCGAACCGGATAAACTGGCGATTGAAGCGCGTAAAACCACCTTTGAGGAAATTTATCTGC
CGTTTCGCGCCGCGCAGGCGGAGCGTGAAGCGGCCCGCTGCCTCACATGCGGGGAACACAGTATCTGCGAATGGACCTGT
CCGCTGCATAACCATATTCCCCAGTGGATCGAACTGGTGAAAGCCGGCGATATTGATGCGGCGGTAGAGCTTTCCCACCA
GACCAACTGTCTGCCGGAAATTACCGGGCGCGTCTGTCCGCAGGATCGGCTATGCGAAGGCGCGTGTACACTCCGCGATG
AGTATGGCGCGGTTACCATCGGCAACATTGAGCGCTATATCTCCGATCGCGCTCTGAGCAAAGGCTGGCGTCCCGACCTG
TCGGACGTACAGAAGAGCGATAAGCGCGTGGCGATTATCGGCGCGGGGCCGGCAGGTCTTGCCTGCGCTGACGTGCTGGC
GCGCCGTCGGGAAATCTTCAGCGCGATGGGGATTCGTTTCGAACTTAACTGCGAAGTAGGGAAAGATATTTCTCTGGAGA
CGCTGCTGGAGAGTTATGACGCCGTCTTTGTCGGGGTAGGAACCTATCGTTCCATGAAGGCTGATTTACCGAATGAAGAC
GCGCCGGGGGTATATGATGCGTTGCCATTCCTCATCGCCAATACCAAACAGGTGATGGGGCTTCCGGCGTTGCCTGACGA
GCCGTTTATTGATACTGCGGGCCTTAACGTGGTTGTGCTGGGCGGCGGTGACACCGCAATGGACTGCGTACGTACGGCGT
TGCGTCATGGCGCTGCCAACGTCACCTGCGCTTATCGCCGCGATGAGGCCAATATGCCAGGGTCGAAAAAAGAGGTGAAA
AACGCGCGGGAAGAGGGCGCGAACTTTGAATTTAACGTTCAGCCAGTTGAGTTGGTGCTGGATACGCACGGGCGCGCCAG
CGGTATTCGCTTTTTGCGTACGCGGCTTGGCGAACCGGATGGTCAGGGGCGACGCCGTCCGGTACCTGTACCGGACAGCG
AGTTCGTGATGCCGGCGGATGCGGTCATTATGGCGTTTGGTTTTCATCCGCATGGTATGTCGTGGCTGGAATCGCATGGC
GTGAAGGTGGATAACTGGGGACGTATTGCCGCCAGCGTCGAGAGCGAGTTTCGTTACCAGACGTCCAACCCGAAAATTTT
CGCTGGCGGCGATGCGGTGCGCGGCGCCGATCTGGTGGTGACGGCGATGGCAGAAGGCCGACATGCCGCGCAGGGGATAC
TCGACTGGTTAGCTAAATAA

Upstream 100 bases:

>100_bases
TGCTTCCTGGGCAGATGAACATTGCCGACCCCGCCTTCGTCAGTTAATAACAATGCTCATATAAAGAATAAGGTTTTTGC
AACCAAAACAGAAGGACGCC

Downstream 100 bases:

>100_bases
GCGTATTTGTAGGCCGGTTAAGGCCTGGAACGGTTAAATGATTTAGTGATAAAAAATCTTAAACTTATTGGCTAACCTTA
CTCCGTTTGCAGAAATGTTG

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 619; Mature: 619

Protein sequence:

>619_residues
MNRFIMANSQQCLGCHACEVACVMAHNDERHVLTPQRYQPRITVIKHQRQRSAVTCHHCEDAPCARSCPNGAIAHINDSV
QVNAQKCIGCKSCVVACPFGTMQMVLTPVAPNQFKASAHKCDLCQGREQGPACVENCPADALQLVTEDSLTRLAKTRRLR
TARQEIRPWHTVDTQHSGTACSKVERMQATPPRGEPDKLAIEARKTTFEEIYLPFRAAQAEREAARCLTCGEHSICEWTC
PLHNHIPQWIELVKAGDIDAAVELSHQTNCLPEITGRVCPQDRLCEGACTLRDEYGAVTIGNIERYISDRALSKGWRPDL
SDVQKSDKRVAIIGAGPAGLACADVLARRREIFSAMGIRFELNCEVGKDISLETLLESYDAVFVGVGTYRSMKADLPNED
APGVYDALPFLIANTKQVMGLPALPDEPFIDTAGLNVVVLGGGDTAMDCVRTALRHGAANVTCAYRRDEANMPGSKKEVK
NAREEGANFEFNVQPVELVLDTHGRASGIRFLRTRLGEPDGQGRRRPVPVPDSEFVMPADAVIMAFGFHPHGMSWLESHG
VKVDNWGRIAASVESEFRYQTSNPKIFAGGDAVRGADLVVTAMAEGRHAAQGILDWLAK

Sequences:

>Translated_619_residues
MNRFIMANSQQCLGCHACEVACVMAHNDERHVLTPQRYQPRITVIKHQRQRSAVTCHHCEDAPCARSCPNGAIAHINDSV
QVNAQKCIGCKSCVVACPFGTMQMVLTPVAPNQFKASAHKCDLCQGREQGPACVENCPADALQLVTEDSLTRLAKTRRLR
TARQEIRPWHTVDTQHSGTACSKVERMQATPPRGEPDKLAIEARKTTFEEIYLPFRAAQAEREAARCLTCGEHSICEWTC
PLHNHIPQWIELVKAGDIDAAVELSHQTNCLPEITGRVCPQDRLCEGACTLRDEYGAVTIGNIERYISDRALSKGWRPDL
SDVQKSDKRVAIIGAGPAGLACADVLARRREIFSAMGIRFELNCEVGKDISLETLLESYDAVFVGVGTYRSMKADLPNED
APGVYDALPFLIANTKQVMGLPALPDEPFIDTAGLNVVVLGGGDTAMDCVRTALRHGAANVTCAYRRDEANMPGSKKEVK
NAREEGANFEFNVQPVELVLDTHGRASGIRFLRTRLGEPDGQGRRRPVPVPDSEFVMPADAVIMAFGFHPHGMSWLESHG
VKVDNWGRIAASVESEFRYQTSNPKIFAGGDAVRGADLVVTAMAEGRHAAQGILDWLAK
>Mature_619_residues
MNRFIMANSQQCLGCHACEVACVMAHNDERHVLTPQRYQPRITVIKHQRQRSAVTCHHCEDAPCARSCPNGAIAHINDSV
QVNAQKCIGCKSCVVACPFGTMQMVLTPVAPNQFKASAHKCDLCQGREQGPACVENCPADALQLVTEDSLTRLAKTRRLR
TARQEIRPWHTVDTQHSGTACSKVERMQATPPRGEPDKLAIEARKTTFEEIYLPFRAAQAEREAARCLTCGEHSICEWTC
PLHNHIPQWIELVKAGDIDAAVELSHQTNCLPEITGRVCPQDRLCEGACTLRDEYGAVTIGNIERYISDRALSKGWRPDL
SDVQKSDKRVAIIGAGPAGLACADVLARRREIFSAMGIRFELNCEVGKDISLETLLESYDAVFVGVGTYRSMKADLPNED
APGVYDALPFLIANTKQVMGLPALPDEPFIDTAGLNVVVLGGGDTAMDCVRTALRHGAANVTCAYRRDEANMPGSKKEVK
NAREEGANFEFNVQPVELVLDTHGRASGIRFLRTRLGEPDGQGRRRPVPVPDSEFVMPADAVIMAFGFHPHGMSWLESHG
VKVDNWGRIAASVESEFRYQTSNPKIFAGGDAVRGADLVVTAMAEGRHAAQGILDWLAK

Specific function: Unknown

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=506, Percent_Identity=27.8656126482213, Blast_Score=134, Evalue=3e-31,
Organism=Escherichia coli, GI1788811, Length=652, Percent_Identity=80.521472392638, Blast_Score=1089, Evalue=0.0,
Organism=Escherichia coli, GI87082180, Length=649, Percent_Identity=51.3097072419106, Blast_Score=651, Evalue=0.0,
Organism=Escherichia coli, GI1789606, Length=459, Percent_Identity=59.9128540305011, Blast_Score=567, Evalue=1e-163,
Organism=Escherichia coli, GI1789067, Length=172, Percent_Identity=49.4186046511628, Blast_Score=162, Evalue=6e-41,
Organism=Escherichia coli, GI1788468, Length=455, Percent_Identity=27.4725274725275, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI2367245, Length=154, Percent_Identity=48.7012987012987, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI87082179, Length=157, Percent_Identity=45.859872611465, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1789079, Length=207, Percent_Identity=36.231884057971, Blast_Score=129, Evalue=7e-31,
Organism=Escherichia coli, GI1789243, Length=421, Percent_Identity=29.9287410926366, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI87082114, Length=188, Percent_Identity=36.7021276595745, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1787122, Length=166, Percent_Identity=33.1325301204819, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787749, Length=175, Percent_Identity=29.1428571428571, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790326, Length=168, Percent_Identity=29.1666666666667, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1787872, Length=158, Percent_Identity=32.2784810126582, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI2367345, Length=157, Percent_Identity=34.3949044585987, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17570289, Length=477, Percent_Identity=31.0272536687631, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71984108, Length=447, Percent_Identity=29.3064876957494, Blast_Score=114, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320030, Length=471, Percent_Identity=30.3609341825902, Blast_Score=171, Evalue=3e-43,
Organism=Drosophila melanogaster, GI24665547, Length=468, Percent_Identity=33.3333333333333, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24665543, Length=468, Percent_Identity=33.3333333333333, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI28574881, Length=468, Percent_Identity=33.3333333333333, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24665539, Length=468, Percent_Identity=33.3333333333333, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24640763, Length=461, Percent_Identity=28.1995661605206, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI18858217, Length=461, Percent_Identity=28.1995661605206, Blast_Score=125, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR013027
- InterPro:   IPR012285
- InterPro:   IPR006006 [H]

Pfam domain/function: PF00037 Fer4; PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 67844; Mature: 67844

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRFIMANSQQCLGCHACEVACVMAHNDERHVLTPQRYQPRITVIKHQRQRSAVTCHHCE
CCCEEECCCCCCCCCHHHEEEEEEECCCCCCCCCCCCCCCEEEEEHHHHHCCCEEEECCC
DAPCARSCPNGAIAHINDSVQVNAQKCIGCKSCVVACPFGTMQMVLTPVAPNQFKASAHK
CCCHHHCCCCCCEEEECCCEEECHHHHCCCCHHEEECCCCCEEEEEECCCCCCCCCCCCC
CDLCQGREQGPACVENCPADALQLVTEDSLTRLAKTRRLRTARQEIRPWHTVDTQHSGTA
CHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
CSKVERMQATPPRGEPDKLAIEARKTTFEEIYLPFRAAQAEREAARCLTCGEHSICEWTC
HHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
PLHNHIPQWIELVKAGDIDAAVELSHQTNCLPEITGRVCPQDRLCEGACTLRDEYGAVTI
CHHHCCHHHHHHHHCCCCCCEEEECCCCCCCHHHHCCCCCHHHHCCCHHEEECCCCEEEE
GNIERYISDRALSKGWRPDLSDVQKSDKRVAIIGAGPAGLACADVLARRREIFSAMGIRF
CCHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCEE
ELNCEVGKDISLETLLESYDAVFVGVGTYRSMKADLPNEDAPGVYDALPFLIANTKQVMG
EEECCCCCCCCHHHHHHHCCEEEEECCCCHHHCCCCCCCCCCCHHHHHHHHHCCCHHHCC
LPALPDEPFIDTAGLNVVVLGGGDTAMDCVRTALRHGAANVTCAYRRDEANMPGSKKEVK
CCCCCCCCCEECCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHH
NAREEGANFEFNVQPVELVLDTHGRASGIRFLRTRLGEPDGQGRRRPVPVPDSEFVMPAD
HHHHCCCCEEEECCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCC
AVIMAFGFHPHGMSWLESHGVKVDNWGRIAASVESEFRYQTSNPKIFAGGDAVRGADLVV
CEEEEECCCCCCCHHHHHCCCEECCCCHHHHHHHHHHEEECCCCEEEECCCCCCCCCEEE
TAMAEGRHAAQGILDWLAK
EEECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNRFIMANSQQCLGCHACEVACVMAHNDERHVLTPQRYQPRITVIKHQRQRSAVTCHHCE
CCCEEECCCCCCCCCHHHEEEEEEECCCCCCCCCCCCCCCEEEEEHHHHHCCCEEEECCC
DAPCARSCPNGAIAHINDSVQVNAQKCIGCKSCVVACPFGTMQMVLTPVAPNQFKASAHK
CCCHHHCCCCCCEEEECCCEEECHHHHCCCCHHEEECCCCCEEEEEECCCCCCCCCCCCC
CDLCQGREQGPACVENCPADALQLVTEDSLTRLAKTRRLRTARQEIRPWHTVDTQHSGTA
CHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
CSKVERMQATPPRGEPDKLAIEARKTTFEEIYLPFRAAQAEREAARCLTCGEHSICEWTC
HHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEC
PLHNHIPQWIELVKAGDIDAAVELSHQTNCLPEITGRVCPQDRLCEGACTLRDEYGAVTI
CHHHCCHHHHHHHHCCCCCCEEEECCCCCCCHHHHCCCCCHHHHCCCHHEEECCCCEEEE
GNIERYISDRALSKGWRPDLSDVQKSDKRVAIIGAGPAGLACADVLARRREIFSAMGIRF
CCHHHHHHHHHHHCCCCCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCEE
ELNCEVGKDISLETLLESYDAVFVGVGTYRSMKADLPNEDAPGVYDALPFLIANTKQVMG
EEECCCCCCCCHHHHHHHCCEEEEECCCCHHHCCCCCCCCCCCHHHHHHHHHCCCHHHCC
LPALPDEPFIDTAGLNVVVLGGGDTAMDCVRTALRHGAANVTCAYRRDEANMPGSKKEVK
CCCCCCCCCEECCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHH
NAREEGANFEFNVQPVELVLDTHGRASGIRFLRTRLGEPDGQGRRRPVPVPDSEFVMPAD
HHHHCCCCEEEECCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCC
AVIMAFGFHPHGMSWLESHGVKVDNWGRIAASVESEFRYQTSNPKIFAGGDAVRGADLVV
CEEEEECCCCCCCHHHHHCCCEECCCCHHHHHHHHHHEEECCCCEEEECCCCCCCCCEEE
TAMAEGRHAAQGILDWLAK
EEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8955321; 9205837; 9278503 [H]