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The map label for this gene is tmcA [H]

Identifier: 29140901

GI number: 29140901

Start: 443445

End: 445460

Strand: Direct

Name: tmcA [H]

Synonym: t0374

Alternate gene names: 29140901

Gene position: 443445-445460 (Clockwise)

Preceding gene: 29140900

Following gene: 29140907

Centisome position: 9.25

GC content: 63.14

Gene sequence:

>2016_bases
ATGTCTGATATCGATGCGCTACGGGCGTTAACGTCGCAAATGACACAGGAAGGCATTCGCCGTTTACTGGTCATCAGCGG
CGATGCGGCGTGGTGCCGGGAACGGGCCGAGGCGATACGCGCTGTATTGCCCGGTGACTGGTGGGTCGCGCCTGACGCGC
CCGCCCAGCCGCGCTGTACGCCACAGGCGTTACAAACGCTGCTGGGCCGTGAATTTCGTCATGCGATATTTGATGCCTGG
CAGGGCTTTGACGCCGCAGCGTTTGCCGCCCTGAGCGGGACCTTGCAGGCCGGAAGTTGGCTGCTTCTGCTGATGCCGCC
GTATGAGACGTGGGAAAGCCGGCCTGATACCGATTCACTGCGCTGGAGCGACTGCGCGCAGCCTATCCCCACACCGCAGT
TTGCACAGCATCTTAAACGGACTCTTTCCCGCGATCCGCAAACGCTGCTTTGGCGACAGCGCCAGCCGTTTTGCTGGCCA
TCTTATCCTTCCCGCGAACGCTGGCGACCCGCCACCGGCGAGCCGCAGCCGGAGCAGGCGGCTATCTTATCGCGTTTACG
TGAAATGCCGCCCGGCGTGGCGACGGTGATTGCCCCCCGTGGGCGCGGCAAATCGGCGCTGGCCGGGCAATTCATCTCAC
AGATGGCGGGCACGGCTATCGTGACCGCACCGGCGAAAACGGCAACGGATATCCTGGCAGCGTTTGCCGGTGAGCGGTTC
TGCTTTATGGCGCCGGATGCGCTGCTGGCGAGCGGGGCAAGAGCCGACTGGCTGGTGGTTGACGAGGCGGCGGCAATCCC
CGCGCCGCTGCTGCTGCAACTGGTTTCGCGCTTTCCCCGCATACTACTCACCACCACCGTTCAGGGCTACGAAGGCACCG
GACGCGGTTTTTTACTTAAGTTTTGCGCCCGTTTTCCGCAGCTTCACCGCTTTACGCTTCGTCAGCCTGTCCGCTGGGCG
CCAGAATGCCCGCTGGAAAATATCGTCAGCGAGGCGCTGATATTCGACGATGAAGCGTTTGCGCAGGCGCCGCATGGCGG
GATAGCAATCTCGGCATTTTACCAGCAGGCCTGGGGGAAGACGCCCGCGTTGCCGAGGGCTGTGTATCAGTTACTGTCGG
GGGCGCACTATCGTACTTCGCCGTTGGATCTGCGCCGAATGATGGATGCGCCAGGACAGCATTTCTTGCAGGCTACGGCG
AATAACCGTGTGGCGGGCGCCCTCTGGCTGGTCGAAGAGGGCGGGTTATCCGCAGAGCTCAGTCAGGCTGTATGGTGCGG
TTTCCGGCGTCCGCGTGGAAATCTGGTGGCGCAGTCGCTGGCGGCGCACGGTAGCGACCCTTTAGCCGCGACGCTGGTCG
GGCGTCGCGTAAGCCGTATCGCGGTGCACCCCGCCCGTCAGCGCGAAGGCATCGGTCAGCAGTTGATTGCCTGCGCGTGC
GAGCAGGCGGCGCAGTGTGATTATCTTTCCGTCAGCTTCGGCTATACGCCGGAGCTGTGGCGCTTCTGGCAACGCTGCGG
CTTTGTGCTGGTACGGATGGGCAGCCATCGGGAGGCGAGCAGCGGTTGCTATACGGCGATGGCGTTATTGCCGCTGAGCG
ACGCGGGACAACGGCTGGCGCAACAGGAACACCGACGTTTGCGCCGCGATGCGGATATCCTGACGCAGTGGAACGGCGAG
GCGATACCGCTGGCGGCGTTGCGCGAACAGGCGCTTAATGATGAAGACTGGCGTGAGCTGGTCGGTTTTGCGTTCGCGCA
CCGCCCGCTACTGACATCGTTAGGTTGCCTGCATCGTTTACTGCAATACAGCGCATTGCCATTGCCGGCGCTGAGAGGGC
GGCTGGAGGAAAAAGCCAGCGATGCCGAACTGTGCGCCCGGCTACGCATTTCAGGCCGTAAAGCTCTGCTGGCGTTGCAG
CGTGCGCAGGCGGCGCAGGCGCTAATTGCGTTGGATGCCGGACGAACGCAGCGTTTGCGCGACGTAATGCCAGGCGGTGG
GGACCATGCCGGATAG

Upstream 100 bases:

>100_bases
CTCAGAACAGCGCTACAGCTGGTTTAAGCGTGGATTTGACAGCGGTGACCCGGCGCAATGTAATACGTTTGGTAAAAACT
TTTGATAAACTGGGGCAGGG

Downstream 100 bases:

>100_bases
CGATACCTGTCCGGCATGTTATCCGGTTACTTTTTCGGCTGATCTTTCTTCGGCCAGTCGTCTTCATCGTCCCACTTATC
GTTAAAATCGCGATGCGGGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MSDIDALRALTSQMTQEGIRRLLVISGDAAWCRERAEAIRAVLPGDWWVAPDAPAQPRCTPQALQTLLGREFRHAIFDAW
QGFDAAAFAALSGTLQAGSWLLLLMPPYETWESRPDTDSLRWSDCAQPIPTPQFAQHLKRTLSRDPQTLLWRQRQPFCWP
SYPSRERWRPATGEPQPEQAAILSRLREMPPGVATVIAPRGRGKSALAGQFISQMAGTAIVTAPAKTATDILAAFAGERF
CFMAPDALLASGARADWLVVDEAAAIPAPLLLQLVSRFPRILLTTTVQGYEGTGRGFLLKFCARFPQLHRFTLRQPVRWA
PECPLENIVSEALIFDDEAFAQAPHGGIAISAFYQQAWGKTPALPRAVYQLLSGAHYRTSPLDLRRMMDAPGQHFLQATA
NNRVAGALWLVEEGGLSAELSQAVWCGFRRPRGNLVAQSLAAHGSDPLAATLVGRRVSRIAVHPARQREGIGQQLIACAC
EQAAQCDYLSVSFGYTPELWRFWQRCGFVLVRMGSHREASSGCYTAMALLPLSDAGQRLAQQEHRRLRRDADILTQWNGE
AIPLAALREQALNDEDWRELVGFAFAHRPLLTSLGCLHRLLQYSALPLPALRGRLEEKASDAELCARLRISGRKALLALQ
RAQAAQALIALDAGRTQRLRDVMPGGGDHAG

Sequences:

>Translated_671_residues
MSDIDALRALTSQMTQEGIRRLLVISGDAAWCRERAEAIRAVLPGDWWVAPDAPAQPRCTPQALQTLLGREFRHAIFDAW
QGFDAAAFAALSGTLQAGSWLLLLMPPYETWESRPDTDSLRWSDCAQPIPTPQFAQHLKRTLSRDPQTLLWRQRQPFCWP
SYPSRERWRPATGEPQPEQAAILSRLREMPPGVATVIAPRGRGKSALAGQFISQMAGTAIVTAPAKTATDILAAFAGERF
CFMAPDALLASGARADWLVVDEAAAIPAPLLLQLVSRFPRILLTTTVQGYEGTGRGFLLKFCARFPQLHRFTLRQPVRWA
PECPLENIVSEALIFDDEAFAQAPHGGIAISAFYQQAWGKTPALPRAVYQLLSGAHYRTSPLDLRRMMDAPGQHFLQATA
NNRVAGALWLVEEGGLSAELSQAVWCGFRRPRGNLVAQSLAAHGSDPLAATLVGRRVSRIAVHPARQREGIGQQLIACAC
EQAAQCDYLSVSFGYTPELWRFWQRCGFVLVRMGSHREASSGCYTAMALLPLSDAGQRLAQQEHRRLRRDADILTQWNGE
AIPLAALREQALNDEDWRELVGFAFAHRPLLTSLGCLHRLLQYSALPLPALRGRLEEKASDAELCARLRISGRKALLALQ
RAQAAQALIALDAGRTQRLRDVMPGGGDHAG
>Mature_670_residues
SDIDALRALTSQMTQEGIRRLLVISGDAAWCRERAEAIRAVLPGDWWVAPDAPAQPRCTPQALQTLLGREFRHAIFDAWQ
GFDAAAFAALSGTLQAGSWLLLLMPPYETWESRPDTDSLRWSDCAQPIPTPQFAQHLKRTLSRDPQTLLWRQRQPFCWPS
YPSRERWRPATGEPQPEQAAILSRLREMPPGVATVIAPRGRGKSALAGQFISQMAGTAIVTAPAKTATDILAAFAGERFC
FMAPDALLASGARADWLVVDEAAAIPAPLLLQLVSRFPRILLTTTVQGYEGTGRGFLLKFCARFPQLHRFTLRQPVRWAP
ECPLENIVSEALIFDDEAFAQAPHGGIAISAFYQQAWGKTPALPRAVYQLLSGAHYRTSPLDLRRMMDAPGQHFLQATAN
NRVAGALWLVEEGGLSAELSQAVWCGFRRPRGNLVAQSLAAHGSDPLAATLVGRRVSRIAVHPARQREGIGQQLIACACE
QAAQCDYLSVSFGYTPELWRFWQRCGFVLVRMGSHREASSGCYTAMALLPLSDAGQRLAQQEHRRLRRDADILTQWNGEA
IPLAALREQALNDEDWRELVGFAFAHRPLLTSLGCLHRLLQYSALPLPALRGRLEEKASDAELCARLRISGRKALLALQR
AQAAQALIALDAGRTQRLRDVMPGGGDHAG

Specific function: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) [H]

COG id: COG1444

COG function: function code R; Predicted P-loop ATPase fused to an acetyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI1788818, Length=662, Percent_Identity=71.6012084592145, Blast_Score=958, Evalue=0.0,
Organism=Drosophila melanogaster, GI24640662, Length=244, Percent_Identity=27.0491803278689, Blast_Score=86, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR013562
- InterPro:   IPR007807 [H]

Pfam domain/function: PF08351 DUF1726; PF05127 DUF699 [H]

EC number: NA

Molecular weight: Translated: 73950; Mature: 73818

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIDALRALTSQMTQEGIRRLLVISGDAAWCRERAEAIRAVLPGDWWVAPDAPAQPRCT
CCHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCC
PQALQTLLGREFRHAIFDAWQGFDAAAFAALSGTLQAGSWLLLLMPPYETWESRPDTDSL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHCCCCCCCCC
RWSDCAQPIPTPQFAQHLKRTLSRDPQTLLWRQRQPFCWPSYPSRERWRPATGEPQPEQA
CHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHH
AILSRLREMPPGVATVIAPRGRGKSALAGQFISQMAGTAIVTAPAKTATDILAAFAGERF
HHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCE
CFMAPDALLASGARADWLVVDEAAAIPAPLLLQLVSRFPRILLTTTVQGYEGTGRGFLLK
EEECCHHHHHCCCCCCEEEECCHHHCCHHHHHHHHHHCCCEEEHEEECCCCCCCCHHHHH
FCARFPQLHRFTLRQPVRWAPECPLENIVSEALIFDDEAFAQAPHGGIAISAFYQQAWGK
HHHHCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCCCEEHHHHHHHHCCC
TPALPRAVYQLLSGAHYRTSPLDLRRMMDAPGQHFLQATANNRVAGALWLVEEGGLSAEL
CCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCEEEEEEEEECCCCCHHH
SQAVWCGFRRPRGNLVAQSLAAHGSDPLAATLVGRRVSRIAVHPARQREGIGQQLIACAC
HHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHH
EQAAQCDYLSVSFGYTPELWRFWQRCGFVLVRMGSHREASSGCYTAMALLPLSDAGQRLA
HHHHCCCEEEEECCCCHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHH
QQEHRRLRRDADILTQWNGEAIPLAALREQALNDEDWRELVGFAFAHRPLLTSLGCLHRL
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LQYSALPLPALRGRLEEKASDAELCARLRISGRKALLALQRAQAAQALIALDAGRTQRLR
HHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
DVMPGGGDHAG
HHCCCCCCCCC
>Mature Secondary Structure 
SDIDALRALTSQMTQEGIRRLLVISGDAAWCRERAEAIRAVLPGDWWVAPDAPAQPRCT
CHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCC
PQALQTLLGREFRHAIFDAWQGFDAAAFAALSGTLQAGSWLLLLMPPYETWESRPDTDSL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHCCCCCCCCC
RWSDCAQPIPTPQFAQHLKRTLSRDPQTLLWRQRQPFCWPSYPSRERWRPATGEPQPEQA
CHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHH
AILSRLREMPPGVATVIAPRGRGKSALAGQFISQMAGTAIVTAPAKTATDILAAFAGERF
HHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHCCCCE
CFMAPDALLASGARADWLVVDEAAAIPAPLLLQLVSRFPRILLTTTVQGYEGTGRGFLLK
EEECCHHHHHCCCCCCEEEECCHHHCCHHHHHHHHHHCCCEEEHEEECCCCCCCCHHHHH
FCARFPQLHRFTLRQPVRWAPECPLENIVSEALIFDDEAFAQAPHGGIAISAFYQQAWGK
HHHHCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCCCEEHHHHHHHHCCC
TPALPRAVYQLLSGAHYRTSPLDLRRMMDAPGQHFLQATANNRVAGALWLVEEGGLSAEL
CCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCEEEEEEEEECCCCCHHH
SQAVWCGFRRPRGNLVAQSLAAHGSDPLAATLVGRRVSRIAVHPARQREGIGQQLIACAC
HHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHH
EQAAQCDYLSVSFGYTPELWRFWQRCGFVLVRMGSHREASSGCYTAMALLPLSDAGQRLA
HHHHCCCEEEEECCCCHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHH
QQEHRRLRRDADILTQWNGEAIPLAALREQALNDEDWRELVGFAFAHRPLLTSLGCLHRL
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LQYSALPLPALRGRLEEKASDAELCARLRISGRKALLALQRAQAAQALIALDAGRTQRLR
HHHCCCCCHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
DVMPGGGDHAG
HHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]