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The map label for this gene is xseA [H]

Identifier: 29140874

GI number: 29140874

Start: 412555

End: 413904

Strand: Reverse

Name: xseA [H]

Synonym: t0345

Alternate gene names: 29140874

Gene position: 413904-412555 (Counterclockwise)

Preceding gene: 29140878

Following gene: 29140856

Centisome position: 8.64

GC content: 58.3

Gene sequence:

>1350_bases
ATGTTATCCTCTCAAACTTCCTCAATTTTTACCGTAAGCCGCCTTAACCAGACGGTTCGTCTGCTGTTAGAACAGGAGAT
GGGACAGGTATGGATCAGCGGCGAGATTTCTAATTTCACGCAGCCTGCGTCGGGCCACTGGTACTTTACGCTCAAAGACG
ATACCGCTCAGGTGCGCTGTGCGATGTTCCGCAACAGCAACCGCCGGGTGACGTTCCGCCCGCAGCACGGGCAGCAGGTG
CTGGTACGCGCCAACATTACGCTGTACGAGCCGCGCGGCGATTATCAAATCATCGCCGAAAGTATGCAGCCGGCTGGCGA
AGGCTTGTTGCAGCAGAAGTATGAGCAGCTAAAAGCCAAACTCCATGCCGAAGGCTTGTTCGATCAGCAGCATAAACAGC
CGTTGCCCTCCCCGGCCCACTGCGTTGGGGTGATCACCTCGAAAACCGGCGCGGCGCTGCACGATATCCTCCACGTGTTG
AAGCGTCGTGACCCATCCCTGCCCGTTATTATCTATCCAACCGCGGTACAGGGCGACGATGCGCCGGGGCAGATCGTTCG
TGCTATCGAACTGGCAAACACGCGCGGCGAGTGCGACGTGCTGATCGTCGGACGCGGCGGCGGTTCGCTGGAAGATTTGT
GGAGTTTTAACGACGAACGCGTGGCGCGGGCTATTTTTGCCAGCCGTATTCCGGTGGTCAGCGCCGTCGGTCACGAAACC
GACGTCACTATCGCCGATTTTGTCGCCGACCTGCGCGCGCCGACGCCATCAGCAGCGGCAGAAATTGTCAGCCGTAACCA
GCAGGAGTTGTTGCGTCAGATCCAGTCCGCCCAGCAGCGTCTGGGCATGGCGATGGACTACTACCTCGCCAACCGCAGCC
GTCGTTTCACGCAGATTTTTCACCGTCTGCAACAACAACATCCGCAACTACGTCTGGCCCGTCAGCAAACCGCGCTGGAA
CGTCTACGCCAACGGATGGGATTTGCGCTTGAGGCCAGGATTAAGCAGGCCACTCAGCGTCAGCAACGCGTAAGTCAACG
CCTGAGCCAGCAAAATCCGCAGCCGCGCATTCACCGCGTGCAGTCGCGCATCCAACAGCTGGAATATCGTCTGACGGAGA
ATATCCGCTCACGGTTAAGCGAACAGCGCGAGCGTTTTGGCAACGCGGTCACGCATCTGGAAGCGGTCAGCCCGTTAGCC
ACGCTGGCGCGCGGCTATACGGTTTCGACGACAACGGACGGCAAGGTGTTGAAAAAGATCAAACAGGTCAAAGCAGGCGA
TATCATGACCACGCGGCTGGAGGACGGCTGGCTTGAAAGTGAAGTCAAATCCGTCACGCCGGGAACGTAA

Upstream 100 bases:

>100_bases
GGTTGCATCTACATTTTTTTGCAAATAGTGCTTGCGATCCCCCGTGAGCAGGTTACTATCGATTGAATAACCTGCTGATT
TAGAATTTGATCCCGCTCAC

Downstream 100 bases:

>100_bases
TCCAACACTCCCCCACCTTTTGCAGCGCGATGTTGGGTTTCGACTTCACCTCAGCCAACCCACGCGCCACGTCGGATAAG
GTGTAGCCACAATCCGACGC

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MLSSQTSSIFTVSRLNQTVRLLLEQEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQV
LVRANITLYEPRGDYQIIAESMQPAGEGLLQQKYEQLKAKLHAEGLFDQQHKQPLPSPAHCVGVITSKTGAALHDILHVL
KRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANTRGECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPVVSAVGHET
DVTIADFVADLRAPTPSAAAEIVSRNQQELLRQIQSAQQRLGMAMDYYLANRSRRFTQIFHRLQQQHPQLRLARQQTALE
RLRQRMGFALEARIKQATQRQQRVSQRLSQQNPQPRIHRVQSRIQQLEYRLTENIRSRLSEQRERFGNAVTHLEAVSPLA
TLARGYTVSTTTDGKVLKKIKQVKAGDIMTTRLEDGWLESEVKSVTPGT

Sequences:

>Translated_449_residues
MLSSQTSSIFTVSRLNQTVRLLLEQEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQV
LVRANITLYEPRGDYQIIAESMQPAGEGLLQQKYEQLKAKLHAEGLFDQQHKQPLPSPAHCVGVITSKTGAALHDILHVL
KRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANTRGECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPVVSAVGHET
DVTIADFVADLRAPTPSAAAEIVSRNQQELLRQIQSAQQRLGMAMDYYLANRSRRFTQIFHRLQQQHPQLRLARQQTALE
RLRQRMGFALEARIKQATQRQQRVSQRLSQQNPQPRIHRVQSRIQQLEYRLTENIRSRLSEQRERFGNAVTHLEAVSPLA
TLARGYTVSTTTDGKVLKKIKQVKAGDIMTTRLEDGWLESEVKSVTPGT
>Mature_449_residues
MLSSQTSSIFTVSRLNQTVRLLLEQEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQV
LVRANITLYEPRGDYQIIAESMQPAGEGLLQQKYEQLKAKLHAEGLFDQQHKQPLPSPAHCVGVITSKTGAALHDILHVL
KRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANTRGECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPVVSAVGHET
DVTIADFVADLRAPTPSAAAEIVSRNQQELLRQIQSAQQRLGMAMDYYLANRSRRFTQIFHRLQQQHPQLRLARQQTALE
RLRQRMGFALEARIKQATQRQQRVSQRLSQQNPQPRIHRVQSRIQQLEYRLTENIRSRLSEQRERFGNAVTHLEAVSPLA
TLARGYTVSTTTDGKVLKKIKQVKAGDIMTTRLEDGWLESEVKSVTPGT

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=447, Percent_Identity=87.248322147651, Blast_Score=805, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 50722; Mature: 50722

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSSQTSSIFTVSRLNQTVRLLLEQEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRC
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCEEEEEECCCHHHHH
AMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIAESMQPAGEGLLQQKYEQLKAK
HHHCCCCCEEEECCCCCCEEEEEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHH
LHAEGLFDQQHKQPLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYPTAVQGDD
HHHHCCCCHHHCCCCCCHHHEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
APGQIVRAIELANTRGECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPVVSAVGHET
CHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHHCCCHHHHCCCCC
DVTIADFVADLRAPTPSAAAEIVSRNQQELLRQIQSAQQRLGMAMDYYLANRSRRFTQIF
CCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHH
HRLQQQHPQLRLARQQTALERLRQRMGFALEARIKQATQRQQRVSQRLSQQNPQPRIHRV
HHHHHHCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
QSRIQQLEYRLTENIRSRLSEQRERFGNAVTHLEAVSPLATLARGYTVSTTTDGKVLKKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHH
KQVKAGDIMTTRLEDGWLESEVKSVTPGT
HHHHCCCEEEEECCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MLSSQTSSIFTVSRLNQTVRLLLEQEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRC
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCEEEEEECCCHHHHH
AMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIAESMQPAGEGLLQQKYEQLKAK
HHHCCCCCEEEECCCCCCEEEEEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHH
LHAEGLFDQQHKQPLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYPTAVQGDD
HHHHCCCCHHHCCCCCCHHHEEEEEECCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
APGQIVRAIELANTRGECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPVVSAVGHET
CHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHHCCCHHHHCCCCC
DVTIADFVADLRAPTPSAAAEIVSRNQQELLRQIQSAQQRLGMAMDYYLANRSRRFTQIF
CCHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHH
HRLQQQHPQLRLARQQTALERLRQRMGFALEARIKQATQRQQRVSQRLSQQNPQPRIHRV
HHHHHHCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
QSRIQQLEYRLTENIRSRLSEQRERFGNAVTHLEAVSPLATLARGYTVSTTTDGKVLKKI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHH
KQVKAGDIMTTRLEDGWLESEVKSVTPGT
HHHHCCCEEEEECCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA