Click here to switch to the map view.

The map label for this gene is acpS [H]

Identifier: 29140814

GI number: 29140814

Start: 318320

End: 318700

Strand: Direct

Name: acpS [H]

Synonym: t0280

Alternate gene names: 29140814

Gene position: 318320-318700 (Clockwise)

Preceding gene: 29140813

Following gene: 29140817

Centisome position: 6.64

GC content: 56.69

Gene sequence:

>381_bases
ATGGCGATTCTCGGCCTGGGAACGGATATTGTAGAGATTGCCCGCATTGAGGCAGTGATCTCCCGTTCCGGCGAACGTCT
GGCAAGGCGTGTGCTCAGTGACAACGAGTGGGCTATCTGGGAGACGCATCAGCAGCCGGTGCGTTTTCTCGCCAAGCGTT
TTGCGGTCAAAGAGGCGGCAGCGAAAGCTTTTGGCACCGGCATCCGCAACGGTCTGGCGTTTAATCAGTTCGAAGTGTTT
AACGATGAGCTGGGAAAACCACGTTTGCGGCTGTGGGGCGAGGCGTTAACGCTGGCGGAAAAACTCGGTGTGGCGCACAT
GCATGTCACGTTGGCCGATGAACGCCATTACGCCTGCGCTACGGTCATTCTGGAAAGTTAG

Upstream 100 bases:

>100_bases
AGCTCAATATCGGTCATGCCATTATTGGTCGGGCGGTGATGACGGGGCTGAAAGAGGCGGTGGCTGAAATGAAACGTTTG
ATGCTGGAAGCGCGCGGCTA

Downstream 100 bases:

>100_bases
ATTTGCCGGATGGCGGCGTAAACACGTTATCTGACCTACAGGCCGATATATTGCCGGCCTGATAAGCATAGCGCCATCAG
GCATTGTTGCGTTGGAAGTG

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS [H]

Number of amino acids: Translated: 126; Mature: 125

Protein sequence:

>126_residues
MAILGLGTDIVEIARIEAVISRSGERLARRVLSDNEWAIWETHQQPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVF
NDELGKPRLRLWGEALTLAEKLGVAHMHVTLADERHYACATVILES

Sequences:

>Translated_126_residues
MAILGLGTDIVEIARIEAVISRSGERLARRVLSDNEWAIWETHQQPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVF
NDELGKPRLRLWGEALTLAEKLGVAHMHVTLADERHYACATVILES
>Mature_125_residues
AILGLGTDIVEIARIEAVISRSGERLARRVLSDNEWAIWETHQQPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFN
DELGKPRLRLWGEALTLAEKLGVAHMHVTLADERHYACATVILES

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein [H]

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family [H]

Homologues:

Organism=Escherichia coli, GI1788916, Length=126, Percent_Identity=94.4444444444444, Blast_Score=243, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: =2.7.8.7 [H]

Molecular weight: Translated: 14070; Mature: 13939

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILGLGTDIVEIARIEAVISRSGERLARRVLSDNEWAIWETHQQPVRFLAKRFAVKEAA
CEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHH
AKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEALTLAEKLGVAHMHVTLADERHYACA
HHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEEEEECCCCEEEE
TVILES
EEEECC
>Mature Secondary Structure 
AILGLGTDIVEIARIEAVISRSGERLARRVLSDNEWAIWETHQQPVRFLAKRFAVKEAA
EEEECCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHH
AKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEALTLAEKLGVAHMHVTLADERHYACA
HHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEEEEEEECCCCEEEE
TVILES
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA