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The map label for this gene is cdsA [H]

Identifier: 29140762

GI number: 29140762

Start: 257002

End: 257859

Strand: Direct

Name: cdsA [H]

Synonym: t0223

Alternate gene names: 29140762

Gene position: 257002-257859 (Clockwise)

Preceding gene: 29140761

Following gene: 29140763

Centisome position: 5.36

GC content: 52.8

Gene sequence:

>858_bases
TTGCTGAAGTATCGCCTGATTTCTGCTTTTGTGTTAATACCCGCGGTCATCGCTGCGCTTTTTTTATTGCCGCCGGTGGG
GTTCGCCATTATTACGCTGGTTGTCTGTATGCTGGCCGCGTGGGAATGGGGGCAGTTAAGCGGTTTCGCCGCGCGTTCAC
AGCGGGTTTGGCTGGCGGTGCTGTGTGGTCTGTTATTGGCGCTGATGTTATTTTTGTTGCCTGAGTATCATCACAACATT
CGTCAACCGCTGGTTGAGATGTCGCTTTGGGCATCGTTAGGATGGTGGGTTGTCGCGCTACTGCTGGTGCTATTTTATCC
CGGTTCGGCGGCAATCTGGCGCAACTCAAAAACATTGCGTCTCATTTTCGGTTTGTTAACTATTGTGCCATTTTTCTGGG
GCATGCTGGCGCTGCGCGCCTGGCACTATGACGAGAATCATTACAGTGGCGCAATATGGTTACTCTATGTCATGATCCTG
GTCTGGGGAGCGGACTCTGGCGCGTATATGTTTGGTAAATTGTTTGGCAAACATAAGCTGGCGCCGAAGGTTTCCCCGGG
TAAAACCTGGCAAGGGTTTATCGGCGGGCTTGCTACGGCTGCCGTGATCTCATGGGGTTACGGTATGTGGGCGAATCTGA
ATGTTGCGCCTGTTATCTTGCTGATTTGCTCTGTGGTGGCGGCTCTGGCTTCTGTACTGGGCGACCTCACCGAGAGTATG
TTTAAGCGCGAAGCAGGAATTAAGGATAGCGGCCACTTGATCCCAGGCCATGGCGGCATTCTGGACCGAATTGACAGTCT
GACGGCTGCCGTACCGGTCTTTGCTTGCCTGTTGTTACTGGTGTTCAGGACGCTCTAA

Upstream 100 bases:

>100_bases
TGAACAAGACTTTGAAGGTGCGCTGCATGCCTTTGCTAATCGAGAGCGTCGTTTCGGCGGTACCGAGCCTGGTGATGACA
AAGCCTGATGGGGGTCGCTT

Downstream 100 bases:

>100_bases
CGGAAGGTTTTATGCTGAGTATTCTCTGGAATCTGGCTGCATTCATCATCGCACTGGGCGTGCTGATCACTGTGCATGAA
TTTGGTCATTTCTGGGTTGC

Product: CDP-diglyceride synthase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MLKYRLISAFVLIPAVIAALFLLPPVGFAIITLVVCMLAAWEWGQLSGFAARSQRVWLAVLCGLLLALMLFLLPEYHHNI
RQPLVEMSLWASLGWWVVALLLVLFYPGSAAIWRNSKTLRLIFGLLTIVPFFWGMLALRAWHYDENHYSGAIWLLYVMIL
VWGADSGAYMFGKLFGKHKLAPKVSPGKTWQGFIGGLATAAVISWGYGMWANLNVAPVILLICSVVAALASVLGDLTESM
FKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLLLLVFRTL

Sequences:

>Translated_285_residues
MLKYRLISAFVLIPAVIAALFLLPPVGFAIITLVVCMLAAWEWGQLSGFAARSQRVWLAVLCGLLLALMLFLLPEYHHNI
RQPLVEMSLWASLGWWVVALLLVLFYPGSAAIWRNSKTLRLIFGLLTIVPFFWGMLALRAWHYDENHYSGAIWLLYVMIL
VWGADSGAYMFGKLFGKHKLAPKVSPGKTWQGFIGGLATAAVISWGYGMWANLNVAPVILLICSVVAALASVLGDLTESM
FKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLLLLVFRTL
>Mature_285_residues
MLKYRLISAFVLIPAVIAALFLLPPVGFAIITLVVCMLAAWEWGQLSGFAARSQRVWLAVLCGLLLALMLFLLPEYHHNI
RQPLVEMSLWASLGWWVVALLLVLFYPGSAAIWRNSKTLRLIFGLLTIVPFFWGMLALRAWHYDENHYSGAIWLLYVMIL
VWGADSGAYMFGKLFGKHKLAPKVSPGKTWQGFIGGLATAAVISWGYGMWANLNVAPVILLICSVVAALASVLGDLTESM
FKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLLLLVFRTL

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=285, Percent_Identity=95.7894736842105, Blast_Score=517, Evalue=1e-148,
Organism=Escherichia coli, GI1787677, Length=117, Percent_Identity=44.4444444444444, Blast_Score=95, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 31395; Mature: 31395

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKYRLISAFVLIPAVIAALFLLPPVGFAIITLVVCMLAAWEWGQLSGFAARSQRVWLAV
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
LCGLLLALMLFLLPEYHHNIRQPLVEMSLWASLGWWVVALLLVLFYPGSAAIWRNSKTLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEECCCCHHH
LIFGLLTIVPFFWGMLALRAWHYDENHYSGAIWLLYVMILVWGADSGAYMFGKLFGKHKL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
APKVSPGKTWQGFIGGLATAAVISWGYGMWANLNVAPVILLICSVVAALASVLGDLTESM
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLLLLVFRTL
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLKYRLISAFVLIPAVIAALFLLPPVGFAIITLVVCMLAAWEWGQLSGFAARSQRVWLAV
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
LCGLLLALMLFLLPEYHHNIRQPLVEMSLWASLGWWVVALLLVLFYPGSAAIWRNSKTLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEECCCCHHH
LIFGLLTIVPFFWGMLALRAWHYDENHYSGAIWLLYVMILVWGADSGAYMFGKLFGKHKL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
APKVSPGKTWQGFIGGLATAAVISWGYGMWANLNVAPVILLICSVVAALASVLGDLTESM
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLLLLVFRTL
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]