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The map label for this gene is copR [H]

Identifier: 161486796

GI number: 161486796

Start: 1886040

End: 1886720

Strand: Direct

Name: copR [H]

Synonym: t1823

Alternate gene names: 161486796

Gene position: 1886040-1886720 (Clockwise)

Preceding gene: 29142251

Following gene: 29142254

Centisome position: 39.36

GC content: 51.1

Gene sequence:

>681_bases
ATGAAGATTTTATTGATTGAAGATAACCAGAAAACCATTGAGTGGGTACGTCAGGGACTCACGGAGGCAGGCTATGTGGT
TGATTATGCCTGTGATGGACGAGACGGATTACACCTAGCCCTTCAGGAACATTATTCATTGATTATTCTTGATATTATGC
TGCCGGGGCTTGATGGATGGCAGGTTTTACGCGCGTTGCGCACTGCATATCAGCCCCCTGTTATTTGCCTGACGGCGCGC
GACTCGGTTGAGGATCGCGTCAAAGGTCTTGAGGCGGGCGCTAATGATTACCTTGTTAAGCCTTTTTCCTTCGCCGAACT
GCTGGCCCGGGTGAGAGCTCAACTCAGACAGCATGTCCCGGTCTTTACCCGACTGACGATCAATGGTCTGGACATGGATG
CCACAAAGCAATCGGTGTTACGAAATGGCAAACCGATTTCCCTGACCCGCAAAGAATTCCTGCTCCTCTGGTTACTGGCG
TCCCGGGCAGGGGAAATCGTGCCCCGAACCGCGATCGCCAGCGAAGTTTGGGGAATTAACTTTGATAGTGAAACCAACAC
CGTTGATGTCGCGATTCGTCGGCTGCGCGCCAAAGTAGACGATCCATTTGAAAAGAAGCTCATTATGACCGTCCAGGGGA
TGGGTTATCGATTACAGGCGGAAACGTCGCAGAATGGTTAA

Upstream 100 bases:

>100_bases
TATCTGGCGCGTCCAGGATTAACCTTACACGGACATGACAATTATGTCATCTTGTTGGAGATTTACGGATTCGCTAACAA
GCCTATGGCATACTGCGTTG

Downstream 100 bases:

>100_bases
GTTATCAATGACGCTGCGCCTGACAATTTCTTTTATCGCCATACTTATCCTCGCCTGTACCGGCATTAGCTGGACGCTCT
ATAACGCGCTGAGCAAAGAA

Product: transcriptional regulator YedW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKILLIEDNQKTIEWVRQGLTEAGYVVDYACDGRDGLHLALQEHYSLIILDIMLPGLDGWQVLRALRTAYQPPVICLTAR
DSVEDRVKGLEAGANDYLVKPFSFAELLARVRAQLRQHVPVFTRLTINGLDMDATKQSVLRNGKPISLTRKEFLLLWLLA
SRAGEIVPRTAIASEVWGINFDSETNTVDVAIRRLRAKVDDPFEKKLIMTVQGMGYRLQAETSQNG

Sequences:

>Translated_226_residues
MKILLIEDNQKTIEWVRQGLTEAGYVVDYACDGRDGLHLALQEHYSLIILDIMLPGLDGWQVLRALRTAYQPPVICLTAR
DSVEDRVKGLEAGANDYLVKPFSFAELLARVRAQLRQHVPVFTRLTINGLDMDATKQSVLRNGKPISLTRKEFLLLWLLA
SRAGEIVPRTAIASEVWGINFDSETNTVDVAIRRLRAKVDDPFEKKLIMTVQGMGYRLQAETSQNG
>Mature_226_residues
MKILLIEDNQKTIEWVRQGLTEAGYVVDYACDGRDGLHLALQEHYSLIILDIMLPGLDGWQVLRALRTAYQPPVICLTAR
DSVEDRVKGLEAGANDYLVKPFSFAELLARVRAQLRQHVPVFTRLTINGLDMDATKQSVLRNGKPISLTRKEFLLLWLLA
SRAGEIVPRTAIASEVWGINFDSETNTVDVAIRRLRAKVDDPFEKKLIMTVQGMGYRLQAETSQNG

Specific function: Probable member of a two-component regulatory system yedW/yedV [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=74.5454545454545, Blast_Score=343, Evalue=8e-96,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=52.4229074889868, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=39.8230088495575, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=37.7272727272727, Blast_Score=138, Evalue=2e-34,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=35.7142857142857, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=33.7777777777778, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=33.4841628959276, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=38.6666666666667, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=30.5936073059361, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=32.4561403508772, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=35.3982300884956, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=32.3144104803493, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=31.7180616740088, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=34.2105263157895, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=33.6448598130841, Blast_Score=70, Evalue=8e-14,
Organism=Escherichia coli, GI1788713, Length=134, Percent_Identity=34.3283582089552, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI48994928, Length=116, Percent_Identity=33.6206896551724, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR006291
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25450; Mature: 25450

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILLIEDNQKTIEWVRQGLTEAGYVVDYACDGRDGLHLALQEHYSLIILDIMLPGLDGW
CEEEEEECCCHHHHHHHHCCCCCCEEEEEEECCCCCEEHEEHHCCCEEEEEECCCCCCHH
QVLRALRTAYQPPVICLTARDSVEDRVKGLEAGANDYLVKPFSFAELLARVRAQLRQHVP
HHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHCCC
VFTRLTINGLDMDATKQSVLRNGKPISLTRKEFLLLWLLASRAGEIVPRTAIASEVWGIN
EEEEEEECCCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCC
FDSETNTVDVAIRRLRAKVDDPFEKKLIMTVQGMGYRLQAETSQNG
CCCCCCHHHHHHHHHHHHCCCHHHHEEEEEECCCCEEEEECCCCCC
>Mature Secondary Structure
MKILLIEDNQKTIEWVRQGLTEAGYVVDYACDGRDGLHLALQEHYSLIILDIMLPGLDGW
CEEEEEECCCHHHHHHHHCCCCCCEEEEEEECCCCCEEHEEHHCCCEEEEEECCCCCCHH
QVLRALRTAYQPPVICLTARDSVEDRVKGLEAGANDYLVKPFSFAELLARVRAQLRQHVP
HHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHCCC
VFTRLTINGLDMDATKQSVLRNGKPISLTRKEFLLLWLLASRAGEIVPRTAIASEVWGIN
EEEEEEECCCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCC
FDSETNTVDVAIRRLRAKVDDPFEKKLIMTVQGMGYRLQAETSQNG
CCCCCCHHHHHHHHHHHHCCCHHHHEEEEEECCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]