Click here to switch to the map view.

The map label for this gene is copS [H]

Identifier: 29142254

GI number: 29142254

Start: 1886713

End: 1888077

Strand: Direct

Name: copS [H]

Synonym: t1824

Alternate gene names: 29142254

Gene position: 1886713-1888077 (Clockwise)

Preceding gene: 161486796

Following gene: 29142255

Centisome position: 39.37

GC content: 51.43

Gene sequence:

>1365_bases
ATGGTTAAGTTATCAATGACGCTGCGCCTGACAATTTCTTTTATCGCCATACTTATCCTCGCCTGTACCGGCATTAGCTG
GACGCTCTATAACGCGCTGAGCAAAGAATTAACGTATCGGGATGATATGACGCTAATAAATCGGGCGGCGCAAATGCAGC
AACTGTTACTGGATGGCGCCAGGCCGGAAAATCTGCCGCTCTATTTCAATCGGATGGTGGATACGAAGCAGGATATCTTA
TTGATCCACTCAGCAACAGGCCATAATGTTGCGATTAATCATAGCGGCATCCCCGACCAACGCTTTAACGAGATTCCGCT
GGCTAAAAACATCACCCGCGAAACCTTATTTCGCCAGGCGGTACAAGGCACGGAGCTGACCGCGGTACGAGTAAACGCCA
GAAGCGGCGATAACCCGCTGACCCTTACTATTGCCAGGCTGGCGACGGAAAGGCGGCAAATGCTGGCGCAATATCGCCGC
AACAGTTTGCTGATTAGCCTTATCGCGATCCTCGTCTGTTCGGCGCTCAGTCCATTAGTCATCAGAAACGGGCTGCGGGC
CATTACGTCGCTCAGCCGACTCACCGCGGCGACAGATAGCGGCACACTTCGCCAGCCGCTGGCGGAACAGGCGTTACCCG
TCGAGCTCAGGCCGCTTGGGCAAGCGCTAAATACCATGCGCCAGAAGCTTTCCGACGATTTTGAACGCCTGAACCAATTT
GCCGACGATCTGGCGCATGAGCTGCGCACGCCGGTTAATATTTTACTGGGGAAGAATCAGGTTATGCTGAGTCAGGAACG
CAGCGCCGAAGAGTATCAACAAGCCCTTGTCGATAATATTGAAGAGCTGGAGGGACTGTCGCGACTGACAGAAAATATTC
TCTTTCTGGCACGCGCGGAGCACCAGAATATAGCGGTAAAAAAACAGCCTGTTTCGCTCAATGCGCTGGTCGAAAATATG
CTGGATTATCTTAGCCCCCTTGCCGAAGAGAAGCACATCTGTTTTATAAATCAATGTCAGGGAACGGTATGGGCTGACGA
AATATTATTACAAAGAGTGCTCTCAAACCTGCTGACGAATGCCATCCGTTATTCTGATGAAAACGCCGTGATACGTATTG
AAAGCGCTTATGATGATAACGTTGCAGAAATTCGGGTCGCTAATCCGGGCAGCCCCACCGCCGATGCGGATAAGCTTTTC
CGGCGTTTTTGGCGAGGAGATAATGCCCGCTACACTGCCGGTTTCGGCCTGGGGTTATCGTTAGTTAACGCGATTGCCCT
ATTGCACGGTGGCTCGGCATCTTACCGCTATGCCGATGAACATAATATCTTTTCGGTTCGTCTGCCTGATAGCGGTGATA
GCTAA

Upstream 100 bases:

>100_bases
ATTCGTCGGCTGCGCGCCAAAGTAGACGATCCATTTGAAAAGAAGCTCATTATGACCGTCCAGGGGATGGGTTATCGATT
ACAGGCGGAAACGTCGCAGA

Downstream 100 bases:

>100_bases
GGTCAGTACAGGTTCTGTTCCCCTTCCCTGCCACAGGGCTGTGGTTATCAATACAACCTCAATAAAAAGAAAATAAAGGA
TGCCGGTAAAGAATATTGCT

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MVKLSMTLRLTISFIAILILACTGISWTLYNALSKELTYRDDMTLINRAAQMQQLLLDGARPENLPLYFNRMVDTKQDIL
LIHSATGHNVAINHSGIPDQRFNEIPLAKNITRETLFRQAVQGTELTAVRVNARSGDNPLTLTIARLATERRQMLAQYRR
NSLLISLIAILVCSALSPLVIRNGLRAITSLSRLTAATDSGTLRQPLAEQALPVELRPLGQALNTMRQKLSDDFERLNQF
ADDLAHELRTPVNILLGKNQVMLSQERSAEEYQQALVDNIEELEGLSRLTENILFLARAEHQNIAVKKQPVSLNALVENM
LDYLSPLAEEKHICFINQCQGTVWADEILLQRVLSNLLTNAIRYSDENAVIRIESAYDDNVAEIRVANPGSPTADADKLF
RRFWRGDNARYTAGFGLGLSLVNAIALLHGGSASYRYADEHNIFSVRLPDSGDS

Sequences:

>Translated_454_residues
MVKLSMTLRLTISFIAILILACTGISWTLYNALSKELTYRDDMTLINRAAQMQQLLLDGARPENLPLYFNRMVDTKQDIL
LIHSATGHNVAINHSGIPDQRFNEIPLAKNITRETLFRQAVQGTELTAVRVNARSGDNPLTLTIARLATERRQMLAQYRR
NSLLISLIAILVCSALSPLVIRNGLRAITSLSRLTAATDSGTLRQPLAEQALPVELRPLGQALNTMRQKLSDDFERLNQF
ADDLAHELRTPVNILLGKNQVMLSQERSAEEYQQALVDNIEELEGLSRLTENILFLARAEHQNIAVKKQPVSLNALVENM
LDYLSPLAEEKHICFINQCQGTVWADEILLQRVLSNLLTNAIRYSDENAVIRIESAYDDNVAEIRVANPGSPTADADKLF
RRFWRGDNARYTAGFGLGLSLVNAIALLHGGSASYRYADEHNIFSVRLPDSGDS
>Mature_454_residues
MVKLSMTLRLTISFIAILILACTGISWTLYNALSKELTYRDDMTLINRAAQMQQLLLDGARPENLPLYFNRMVDTKQDIL
LIHSATGHNVAINHSGIPDQRFNEIPLAKNITRETLFRQAVQGTELTAVRVNARSGDNPLTLTIARLATERRQMLAQYRR
NSLLISLIAILVCSALSPLVIRNGLRAITSLSRLTAATDSGTLRQPLAEQALPVELRPLGQALNTMRQKLSDDFERLNQF
ADDLAHELRTPVNILLGKNQVMLSQERSAEEYQQALVDNIEELEGLSRLTENILFLARAEHQNIAVKKQPVSLNALVENM
LDYLSPLAEEKHICFINQCQGTVWADEILLQRVLSNLLTNAIRYSDENAVIRIESAYDDNVAEIRVANPGSPTADADKLF
RRFWRGDNARYTAGFGLGLSLVNAIALLHGGSASYRYADEHNIFSVRLPDSGDS

Specific function: Probable member of a two-component regulatory system yedW/yedV. May activate yedW by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788279, Length=450, Percent_Identity=54.6666666666667, Blast_Score=488, Evalue=1e-139,
Organism=Escherichia coli, GI1786783, Length=291, Percent_Identity=33.3333333333333, Blast_Score=158, Evalue=8e-40,
Organism=Escherichia coli, GI1786912, Length=217, Percent_Identity=29.0322580645161, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1790861, Length=265, Percent_Identity=30.5660377358491, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788393, Length=243, Percent_Identity=27.5720164609054, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790551, Length=231, Percent_Identity=30.7359307359307, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87082128, Length=319, Percent_Identity=26.3322884012539, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790346, Length=240, Percent_Identity=29.5833333333333, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787894, Length=221, Percent_Identity=31.6742081447964, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788713, Length=218, Percent_Identity=28.4403669724771, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788549, Length=211, Percent_Identity=27.9620853080569, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789403, Length=240, Percent_Identity=27.9166666666667, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI48994928, Length=220, Percent_Identity=23.1818181818182, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI145693157, Length=243, Percent_Identity=24.6913580246914, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI87081816, Length=289, Percent_Identity=25.6055363321799, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=26.3829787234043, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR006290
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50715; Mature: 50715

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKLSMTLRLTISFIAILILACTGISWTLYNALSKELTYRDDMTLINRAAQMQQLLLDGA
CEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
RPENLPLYFNRMVDTKQDILLIHSATGHNVAINHSGIPDQRFNEIPLAKNITRETLFRQA
CCCCCCCHHHHHHCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
VQGTELTAVRVNARSGDNPLTLTIARLATERRQMLAQYRRNSLLISLIAILVCSALSPLV
HCCCCEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IRNGLRAITSLSRLTAATDSGTLRQPLAEQALPVELRPLGQALNTMRQKLSDDFERLNQF
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ADDLAHELRTPVNILLGKNQVMLSQERSAEEYQQALVDNIEELEGLSRLTENILFLARAE
HHHHHHHHCCCCEEEECCCCEEECHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
HQNIAVKKQPVSLNALVENMLDYLSPLAEEKHICFINQCQGTVWADEILLQRVLSNLLTN
CCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
AIRYSDENAVIRIESAYDDNVAEIRVANPGSPTADADKLFRRFWRGDNARYTAGFGLGLS
HHHCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEECHHHHHH
LVNAIALLHGGSASYRYADEHNIFSVRLPDSGDS
HHHHHHHHCCCCCCCEECCCCCEEEEECCCCCCC
>Mature Secondary Structure
MVKLSMTLRLTISFIAILILACTGISWTLYNALSKELTYRDDMTLINRAAQMQQLLLDGA
CEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
RPENLPLYFNRMVDTKQDILLIHSATGHNVAINHSGIPDQRFNEIPLAKNITRETLFRQA
CCCCCCCHHHHHHCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
VQGTELTAVRVNARSGDNPLTLTIARLATERRQMLAQYRRNSLLISLIAILVCSALSPLV
HCCCCEEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
IRNGLRAITSLSRLTAATDSGTLRQPLAEQALPVELRPLGQALNTMRQKLSDDFERLNQF
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ADDLAHELRTPVNILLGKNQVMLSQERSAEEYQQALVDNIEELEGLSRLTENILFLARAE
HHHHHHHHCCCCEEEECCCCEEECHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
HQNIAVKKQPVSLNALVENMLDYLSPLAEEKHICFINQCQGTVWADEILLQRVLSNLLTN
CCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHH
AIRYSDENAVIRIESAYDDNVAEIRVANPGSPTADADKLFRRFWRGDNARYTAGFGLGLS
HHHCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCEEEECHHHHHH
LVNAIALLHGGSASYRYADEHNIFSVRLPDSGDS
HHHHHHHHCCCCCCCEECCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]