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The map label for this gene is entC [H]

Identifier: 161486793

GI number: 161486793

Start: 2339553

End: 2340728

Strand: Reverse

Name: entC [H]

Synonym: t2273

Alternate gene names: 161486793

Gene position: 2340728-2339553 (Counterclockwise)

Preceding gene: 29142675

Following gene: 29142672

Centisome position: 48.85

GC content: 58.76

Gene sequence:

>1176_bases
ATGGATATGTCACTGGCCGAGGACGCTCAGGAGACAATGGCAACGCTTGCTCCCGATCGCTTTTTCTTCATGTCGCCGTA
TCGCAGTTTTACCACTTCCGGGTGCTTCGCCCGTTATACCGAGCCTGCGGTTGCCGGAGATTCGCCGGATAGCCCTTTCC
AGCAGAAATTGCGCCAGCAGTTTGCCGAGGCCAAATCGCAGGGCATCGCCAACCCTATCCTGGTGGGGGCGATCCCCTTT
GATACCCGTCAGCCGTCGTCGCTATTTATCCCGATGGCGTGGCAGTCCTTTTCCCGCCAGCAAAAGCAGCGCACGGCGCG
TTATTTTACTGACCATCAGCCGCTGACGGTGACGGCGCGAAAGGCGATTCCGGAGCAGGATGCTTTTGAAGCGATGGTCG
CACGCGCGGCTATGCTGACCGCCACGCCAGACGTCGATAAAGTGGTGCTTTCCCGGCTGATAGATATCACCACTGATGTG
GCGGTGGATAGCGGAGCATTGCTGGAGCGGCTGGTTGCGCAGAATCCAGTTAGTTACAACTTCCATGTGCCACTGGCGGA
TGGCGGCGTTCTGCTGGGCGCCAGCCCCGAATTGCTGCTACGCAAGGAGGGCGAGCGGTTTAGTTCGCTGCCGTTAGCAG
GCTCGGCACGCCGACAGCCCGATGACGTTCTGGATCGCGAGGCGGGAAACCGACTGCTGGCTTCACAAAAAGATCGCCAT
GAACATGAGCTGGTGACGCAGGCGATGAAGCAGATCCTGCGCGATCGCAGCACGGAACTGCAATTACCTTCCTCTCCGCA
GTTGATCACCACGCCGACGCTATGGCATCTCGGTACGCCGTTTGAGGGCAAGGCCAACGCCGGAGAAAACGCGCTTACGC
TGGCCTGTCTGCTGCATCCGACCCCTGCGTTAAGCGGTTTCCCCCATCAGGTCGCGAAAAAGCTGATTGCTGAACTGGAG
CCGTTCGATCGTGAACTGTTTGGCGGCATTGTCGGCTGGTGCGATGCCGAAGGAAACGGCGAGTGGGTAGTGACGATTCG
TTGTGCGAAATTGCACGGTAATCAGGTGCGCCTGTTCGCCGGCGCCGGGATTGTTCCTGCCTCTTCGCCAGTCGGCGAGT
GGCGGGAAACCGGCGTCAAGCTCTCTACGATGTTGAACGTTTTTGGACTGCATTAA

Upstream 100 bases:

>100_bases
CGGGCATAGATAACTGTGTGACCGGGGTTTCTGATCGCAGCCAACAAAGAGGCAGCTTGAAAGATGAAGTGTATATAAGC
CTTTATCATTGGAGGATGAT

Downstream 100 bases:

>100_bases
GGAACGATGATGCGTATACCTTTCACCCGTTGGCCGGATGAATTTGCCCGCCGTTATCGTGAAAAAGGCTACTGGCAAGA
CGTGCCGTTGACCGATATTC

Product: isochorismate synthase

Products: NA

Alternate protein names: Isochorismate mutase [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MDMSLAEDAQETMATLAPDRFFFMSPYRSFTTSGCFARYTEPAVAGDSPDSPFQQKLRQQFAEAKSQGIANPILVGAIPF
DTRQPSSLFIPMAWQSFSRQQKQRTARYFTDHQPLTVTARKAIPEQDAFEAMVARAAMLTATPDVDKVVLSRLIDITTDV
AVDSGALLERLVAQNPVSYNFHVPLADGGVLLGASPELLLRKEGERFSSLPLAGSARRQPDDVLDREAGNRLLASQKDRH
EHELVTQAMKQILRDRSTELQLPSSPQLITTPTLWHLGTPFEGKANAGENALTLACLLHPTPALSGFPHQVAKKLIAELE
PFDRELFGGIVGWCDAEGNGEWVVTIRCAKLHGNQVRLFAGAGIVPASSPVGEWRETGVKLSTMLNVFGLH

Sequences:

>Translated_391_residues
MDMSLAEDAQETMATLAPDRFFFMSPYRSFTTSGCFARYTEPAVAGDSPDSPFQQKLRQQFAEAKSQGIANPILVGAIPF
DTRQPSSLFIPMAWQSFSRQQKQRTARYFTDHQPLTVTARKAIPEQDAFEAMVARAAMLTATPDVDKVVLSRLIDITTDV
AVDSGALLERLVAQNPVSYNFHVPLADGGVLLGASPELLLRKEGERFSSLPLAGSARRQPDDVLDREAGNRLLASQKDRH
EHELVTQAMKQILRDRSTELQLPSSPQLITTPTLWHLGTPFEGKANAGENALTLACLLHPTPALSGFPHQVAKKLIAELE
PFDRELFGGIVGWCDAEGNGEWVVTIRCAKLHGNQVRLFAGAGIVPASSPVGEWRETGVKLSTMLNVFGLH
>Mature_391_residues
MDMSLAEDAQETMATLAPDRFFFMSPYRSFTTSGCFARYTEPAVAGDSPDSPFQQKLRQQFAEAKSQGIANPILVGAIPF
DTRQPSSLFIPMAWQSFSRQQKQRTARYFTDHQPLTVTARKAIPEQDAFEAMVARAAMLTATPDVDKVVLSRLIDITTDV
AVDSGALLERLVAQNPVSYNFHVPLADGGVLLGASPELLLRKEGERFSSLPLAGSARRQPDDVLDREAGNRLLASQKDRH
EHELVTQAMKQILRDRSTELQLPSSPQLITTPTLWHLGTPFEGKANAGENALTLACLLHPTPALSGFPHQVAKKLIAELE
PFDRELFGGIVGWCDAEGNGEWVVTIRCAKLHGNQVRLFAGAGIVPASSPVGEWRETGVKLSTMLNVFGLH

Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]

COG id: COG1169

COG function: function code HQ; Isochorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the isochorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786809, Length=391, Percent_Identity=84.3989769820972, Blast_Score=693, Evalue=0.0,
Organism=Escherichia coli, GI87082077, Length=277, Percent_Identity=32.8519855595668, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1788114, Length=201, Percent_Identity=27.363184079602, Blast_Score=69, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=220, Percent_Identity=27.7272727272727, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR015890
- InterPro:   IPR004561 [H]

Pfam domain/function: PF00425 Chorismate_bind [H]

EC number: =5.4.4.2 [H]

Molecular weight: Translated: 42846; Mature: 42846

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMSLAEDAQETMATLAPDRFFFMSPYRSFTTSGCFARYTEPAVAGDSPDSPFQQKLRQQ
CCCCHHHHHHHHHHHHCCCCEEEECCHHHHHCCCCHHHCCCCCCCCCCCCCHHHHHHHHH
FAEAKSQGIANPILVGAIPFDTRQPSSLFIPMAWQSFSRQQKQRTARYFTDHQPLTVTAR
HHHHHHCCCCCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEHH
KAIPEQDAFEAMVARAAMLTATPDVDKVVLSRLIDITTDVAVDSGALLERLVAQNPVSYN
HCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEE
FHVPLADGGVLLGASPELLLRKEGERFSSLPLAGSARRQPDDVLDREAGNRLLASQKDRH
EEEEECCCCEEECCCCHHHHCCCCCHHHCCCCCCCCCCCCHHHHHHHHCCHHHHCCCHHH
EHELVTQAMKQILRDRSTELQLPSSPQLITTPTLWHLGTPFEGKANAGENALTLACLLHP
HHHHHHHHHHHHHHCCCCEEECCCCCCEEECCCCEECCCCCCCCCCCCCCEEEEEEEECC
TPALSGFPHQVAKKLIAELEPFDRELFGGIVGWCDAEGNGEWVVTIRCAKLHGNQVRLFA
CCCCCCCHHHHHHHHHHHCCHHHHHHHCCCEEEEECCCCCCEEEEEEEEEECCCEEEEEE
GAGIVPASSPVGEWRETGVKLSTMLNVFGLH
CCCCCCCCCCCHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure
MDMSLAEDAQETMATLAPDRFFFMSPYRSFTTSGCFARYTEPAVAGDSPDSPFQQKLRQQ
CCCCHHHHHHHHHHHHCCCCEEEECCHHHHHCCCCHHHCCCCCCCCCCCCCHHHHHHHHH
FAEAKSQGIANPILVGAIPFDTRQPSSLFIPMAWQSFSRQQKQRTARYFTDHQPLTVTAR
HHHHHHCCCCCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEHH
KAIPEQDAFEAMVARAAMLTATPDVDKVVLSRLIDITTDVAVDSGALLERLVAQNPVSYN
HCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCEE
FHVPLADGGVLLGASPELLLRKEGERFSSLPLAGSARRQPDDVLDREAGNRLLASQKDRH
EEEEECCCCEEECCCCHHHHCCCCCHHHCCCCCCCCCCCCHHHHHHHHCCHHHHCCCHHH
EHELVTQAMKQILRDRSTELQLPSSPQLITTPTLWHLGTPFEGKANAGENALTLACLLHP
HHHHHHHHHHHHHHCCCCEEECCCCCCEEECCCCEECCCCCCCCCCCCCCEEEEEEEECC
TPALSGFPHQVAKKLIAELEPFDRELFGGIVGWCDAEGNGEWVVTIRCAKLHGNQVRLFA
CCCCCCCHHHHHHHHHHHCCHHHHHHHCCCEEEEECCCCCCEEEEEEEEEECCCEEEEEE
GAGIVPASSPVGEWRETGVKLSTMLNVFGLH
CCCCCCCCCCCHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]