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The map label for this gene is cutC [C]

Identifier: 28378818

GI number: 28378818

Start: 2002853

End: 2003491

Strand: Direct

Name: cutC [C]

Synonym: lp_2220

Alternate gene names: 28378818

Gene position: 2002853-2003491 (Clockwise)

Preceding gene: 28378817

Following gene: 28378822

Centisome position: 60.54

GC content: 49.77

Gene sequence:

>639_bases
ATGTTATTAAAAGAAGTCTGTGTTGAAAATTACACTAACATTCCCGCAGCCATTGCGGCCGGTGCCAATCGGATCGAACT
CAACGATAACCTATCCGTTGGCGGTACAACGGTCAGTCGTGGTGTAATGGCTGAGGCAGCCAAGTATACCAGTGAACATC
ACGTGCCCCTAGTGACCATGATTCGCCCCCGTGGTGGCAATTTCGTTTATAATGATACGGAATTAAAAATCATGGAAGCG
GACCTGCTACAGGCTCAATCATTAGGTGTTGATGGTGTCGCATTTGGTGCTTTGACTGCGGATAATCAGCTTGACGAAGA
AGCCTTAGCGTTATTAATTGGTGCAGCCGGTGGCATGTCGATCACCTTCCACATGGCTTTTGACGCCATCCCTGAAAATC
AACAAGCCGCGGCAATTGACTGGTTAGTAGACCATGACGTCGATCGCATTTTGACACATGGCGGCCCACTTGATCAGCCG
ATTGCTGACTGTGTCCCCCACTTGCAAACGACGATCAAACAGGCCGCTGGCCGAATTCAGATCCTACCTGGTGGTGGCAT
TACCACCGCCAATGTCGCCGACATCACCACAACGCTCGGCGTCAAACAGGCCCATGGGACCAAGATTATTAATTACTAA

Upstream 100 bases:

>100_bases
GTATGCACGCGACTTAACGAGTGGTAAACTAAGTCTATTACAAAAGGACGTTACTGTGCCTGAAGGCGTTTGCGTCCGTT
TCTAGTAAAGGATGAAACTC

Downstream 100 bases:

>100_bases
GAACTGCCAAAAAGGCGCATCTCATTTTTTGAGATGCGCCTTTTGATTGGCGAAGTAAACTAAAAAATTAGACCATTAAT
CACGGTTATTCAATGGTCTA

Product: copper homeostasis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MLLKEVCVENYTNIPAAIAAGANRIELNDNLSVGGTTVSRGVMAEAAKYTSEHHVPLVTMIRPRGGNFVYNDTELKIMEA
DLLQAQSLGVDGVAFGALTADNQLDEEALALLIGAAGGMSITFHMAFDAIPENQQAAAIDWLVDHDVDRILTHGGPLDQP
IADCVPHLQTTIKQAAGRIQILPGGGITTANVADITTTLGVKQAHGTKIINY

Sequences:

>Translated_212_residues
MLLKEVCVENYTNIPAAIAAGANRIELNDNLSVGGTTVSRGVMAEAAKYTSEHHVPLVTMIRPRGGNFVYNDTELKIMEA
DLLQAQSLGVDGVAFGALTADNQLDEEALALLIGAAGGMSITFHMAFDAIPENQQAAAIDWLVDHDVDRILTHGGPLDQP
IADCVPHLQTTIKQAAGRIQILPGGGITTANVADITTTLGVKQAHGTKIINY
>Mature_212_residues
MLLKEVCVENYTNIPAAIAAGANRIELNDNLSVGGTTVSRGVMAEAAKYTSEHHVPLVTMIRPRGGNFVYNDTELKIMEA
DLLQAQSLGVDGVAFGALTADNQLDEEALALLIGAAGGMSITFHMAFDAIPENQQAAAIDWLVDHDVDRILTHGGPLDQP
IADCVPHLQTTIKQAAGRIQILPGGGITTANVADITTTLGVKQAHGTKIINY

Specific function: Involved In Copper Homeostasis. [C]

COG id: COG3142

COG function: function code P; Uncharacterized protein involved in copper resistance

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutC family [H]

Homologues:

Organism=Homo sapiens, GI148596990, Length=204, Percent_Identity=39.2156862745098, Blast_Score=143, Evalue=9e-35,
Organism=Escherichia coli, GI87081995, Length=216, Percent_Identity=27.7777777777778, Blast_Score=80, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17556905, Length=211, Percent_Identity=31.2796208530806, Blast_Score=93, Evalue=8e-20,
Organism=Drosophila melanogaster, GI21355415, Length=206, Percent_Identity=31.0679611650485, Blast_Score=99, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005627 [H]

Pfam domain/function: PF03932 CutC [H]

EC number: NA

Molecular weight: Translated: 22394; Mature: 22394

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLKEVCVENYTNIPAAIAAGANRIELNDNLSVGGTTVSRGVMAEAAKYTSEHHVPLVTM
CCHHHHHHHCCCCCCHHHHCCCCEEEECCCCEECCCHHHHHHHHHHHHHCCCCCCEEEEE
IRPRGGNFVYNDTELKIMEADLLQAQSLGVDGVAFGALTADNQLDEEALALLIGAAGGMS
EECCCCCEEECCCEEEEEHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHEEEECCCCCE
ITFHMAFDAIPENQQAAAIDWLVDHDVDRILTHGGPLDQPIADCVPHLQTTIKQAAGRIQ
EEEEEEECCCCCCCCCEEEHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCEEE
ILPGGGITTANVADITTTLGVKQAHGTKIINY
EEECCCCCCCCHHHHHHHHCCCCCCCCEECCC
>Mature Secondary Structure
MLLKEVCVENYTNIPAAIAAGANRIELNDNLSVGGTTVSRGVMAEAAKYTSEHHVPLVTM
CCHHHHHHHCCCCCCHHHHCCCCEEEECCCCEECCCHHHHHHHHHHHHHCCCCCCEEEEE
IRPRGGNFVYNDTELKIMEADLLQAQSLGVDGVAFGALTADNQLDEEALALLIGAAGGMS
EECCCCCEEECCCEEEEEHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHEEEECCCCCE
ITFHMAFDAIPENQQAAAIDWLVDHDVDRILTHGGPLDQPIADCVPHLQTTIKQAAGRIQ
EEEEEEECCCCCCCCCEEEHHHHHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCEEE
ILPGGGITTANVADITTTLGVKQAHGTKIINY
EEECCCCCCCCHHHHHHHHCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA