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The map label for this gene is plsC [H]

Identifier: 28378691

GI number: 28378691

Start: 1862349

End: 1862987

Strand: Direct

Name: plsC [H]

Synonym: lp_2060

Alternate gene names: 28378691

Gene position: 1862349-1862987 (Clockwise)

Preceding gene: 28378687

Following gene: 28378694

Centisome position: 56.29

GC content: 47.42

Gene sequence:

>639_bases
GTGATGTTTTATTCATTTATGCGCGGACTAGTCCGGCTAATCATCACCATTATTAACGGTCGGCCCCGCTATCAAGGACG
GGAAAACCTACCAGAGGGGGCCTATATCTTAGTTGGGCCACACCGCACGTGGTTTGACCCGTTGTACTATGCACTGGCTG
GCAGTCCAATGAAATTTAGCTTTATGGCCAAGGAAGAACTATTTAAGAATCCCGTTCTGCGGTTCATTCTCGTTCATGCG
AACGCCTTTCCTGTCAATCGGCAACATCCAGGACCTTCAGCAATCAAGACCCCCGTCAAATTTTTGCGCAGCGGTAAGCT
TTCACTAATCATGTTTCCATCAGGAACGCGCCACTCACAAGAACTTAAGGGCGGTGCAACCGTCATCGCTAAGATGGCCG
GTGTTCCACTAGTCCCAACCGTTTACCAAGGCCCATTGACCTTCAAACAACTCTTTAGCCGTCAGCGGGTTACCGTCCGT
TTCGGTCAACCGATTGATATTGATCGTAAACTGAAATTGGATGAAGCTGGTCAAAAACAAATTGAGACTAAAATGTTGCA
CGCTTTTGACGACTTGGATCGTCAAATCGACCCAACGTTCAAATACGTTGATCCTGCTACAACCCGTCAGAAACATTAA

Upstream 100 bases:

>100_bases
ACCTCTCCATTCAATTCTTCGCACAGCTATCATACAATTAACTTGCAGAATTTGCCAAATTTCGTCATACTGTGAGCAGT
TATTAAACGAAAGGAAGATC

Downstream 100 bases:

>100_bases
GTTCGATAATAAAAAAGTGTCGGTGATCGCAATTTAAAGCGAGCCGACACTTTTTACTACTTGTTATCGTTTTTAGATGC
AGCTTTCATCGAATTCAACA

Product: 1-acylglycerol-3-phosphate O-acyltransferase

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; 1-acyl-G3P acyltransferase; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MMFYSFMRGLVRLIITIINGRPRYQGRENLPEGAYILVGPHRTWFDPLYYALAGSPMKFSFMAKEELFKNPVLRFILVHA
NAFPVNRQHPGPSAIKTPVKFLRSGKLSLIMFPSGTRHSQELKGGATVIAKMAGVPLVPTVYQGPLTFKQLFSRQRVTVR
FGQPIDIDRKLKLDEAGQKQIETKMLHAFDDLDRQIDPTFKYVDPATTRQKH

Sequences:

>Translated_212_residues
MMFYSFMRGLVRLIITIINGRPRYQGRENLPEGAYILVGPHRTWFDPLYYALAGSPMKFSFMAKEELFKNPVLRFILVHA
NAFPVNRQHPGPSAIKTPVKFLRSGKLSLIMFPSGTRHSQELKGGATVIAKMAGVPLVPTVYQGPLTFKQLFSRQRVTVR
FGQPIDIDRKLKLDEAGQKQIETKMLHAFDDLDRQIDPTFKYVDPATTRQKH
>Mature_212_residues
MMFYSFMRGLVRLIITIINGRPRYQGRENLPEGAYILVGPHRTWFDPLYYALAGSPMKFSFMAKEELFKNPVLRFILVHA
NAFPVNRQHPGPSAIKTPVKFLRSGKLSLIMFPSGTRHSQELKGGATVIAKMAGVPLVPTVYQGPLTFKQLFSRQRVTVR
FGQPIDIDRKLKLDEAGQKQIETKMLHAFDDLDRQIDPTFKYVDPATTRQKH

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) by incorporating an acyl moiety at the 2 position. This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: 2.3.1.51

Molecular weight: Translated: 24219; Mature: 24219

Theoretical pI: Translated: 10.83; Mature: 10.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMFYSFMRGLVRLIITIINGRPRYQGRENLPEGAYILVGPHRTWFDPLYYALAGSPMKFS
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCEEEE
FMAKEELFKNPVLRFILVHANAFPVNRQHPGPSAIKTPVKFLRSGKLSLIMFPSGTRHSQ
HHHHHHHHHCHHHEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHH
ELKGGATVIAKMAGVPLVPTVYQGPLTFKQLFSRQRVTVRFGQPIDIDRKLKLDEAGQKQ
HHCCHHHHHHHHCCCCCCCHHCCCCCHHHHHHCCCCEEEEECCCCCCCCEECCCHHHHHH
IETKMLHAFDDLDRQIDPTFKYVDPATTRQKH
HHHHHHHHHHHHHHHCCCCEEECCCCCCCCCC
>Mature Secondary Structure
MMFYSFMRGLVRLIITIINGRPRYQGRENLPEGAYILVGPHRTWFDPLYYALAGSPMKFS
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCEEEE
FMAKEELFKNPVLRFILVHANAFPVNRQHPGPSAIKTPVKFLRSGKLSLIMFPSGTRHSQ
HHHHHHHHHCHHHEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHH
ELKGGATVIAKMAGVPLVPTVYQGPLTFKQLFSRQRVTVRFGQPIDIDRKLKLDEAGQKQ
HHCCHHHHHHHHCCCCCCCHHCCCCCHHHHHHCCCCEEEEECCCCCCCCEECCCHHHHHH
IETKMLHAFDDLDRQIDPTFKYVDPATTRQKH
HHHHHHHHHHHHHHHCCCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11544234 [H]