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The map label for this gene is tagO [H]

Identifier: 28377593

GI number: 28377593

Start: 669270

End: 670367

Strand: Direct

Name: tagO [H]

Synonym: lp_0730

Alternate gene names: 28377593

Gene position: 669270-670367 (Clockwise)

Preceding gene: 28377592

Following gene: 28377594

Centisome position: 20.23

GC content: 43.17

Gene sequence:

>1098_bases
ATGATCAGATTTGAAATCCTAGTAAGCCTAGTGGCGACCATGATACTTTCTGCGATCTTGACGCCGTTTGTGCGGAAACT
TGCATTTAAAATTGGTGCCGTGGATAAACCAAATGTACGACGGGTCAATAAAATTCCAATGCCGACAATGGGAGGCTTGG
CTATTTTTATCTCTTACACCGTTGGGACGACTGTGTTGTATCTCATGCACCAGTTTCCCAGTCGCATTTTTTTCGCACTA
CTCGGTGGTGAGCTGATCATTATTGCGACTGGTGTTATCGATGATATTTATGAGCTAAAACCACGGCAAAAAATGTTAGG
GATTACGTTAGCCGCTTTGGAGGTCTACTTTATTGGTGGTATCCGAATGACGACCTTCACGTTCCCGTTGCTGGGGCTGA
TTCACTTTCAGTGGCTGAGTTTACCGGTGACTTTACTGTGGATACTGGCTATCACGAATGCGGTGAACTTAATTGATGGA
CTGGATGGGTTAGCTACCGGTGTTTCGATTATTTCGTTGAGTACCATGGGGATCATCGGGTTGTTCTTCTTGAATGCTAA
TATGTTCGTTTCGTTGTTGATTTTTACTTTAGTTGCGGCGATGATTGGCTTTCTTCCGTATAATTTCTTTCCAGCTAGAA
TTTATCTCGGTGATACCGGTTCGTTGTTTATCGGCTTTATGACGGCTGTGTTCTCATTATTTGGATTGAAAAATGTCACC
TTAATCTCAGTTGGTATTCCGGTTATGATCCTGGGAGTGCCAATTACGGATACGGTGTATGCGATGATTCGACGGATCCT
GAATAAGAAGCCCATTTCGCAAGCGGATAAGCATCATTTGCACCACCGCTTGATGCAATTAGGATTGACCCATCGACAGA
CTGTGATGGTAATTTATGGGATTGCACTTATTTTCTCATTTATTTCATTGCTCTATCCGATCTCATCTATTTGGGGTTCT
GTGTTATTGACGATTGGTTTATTATTTGGGCTAGAGTTATTCGTTGAAGCAATCGGATTAGCTGGTGACAATCGGCAACC
GCTACTGGATTGGATCAAACGGACCGTCGCGCGTTTGACCTCCAAGAGTAATCATTAA

Upstream 100 bases:

>100_bases
GAATTGTGTTGCCTTTACTAAGTTTTAGTGAAGCGAGTTGTCAAGCGTCACTGGGATTTGTATAATTATCGTAATAGAGT
GAGAAGGGAGTTACGCACAA

Downstream 100 bases:

>100_bases
AAACCAAATAAATCATTGAAAATTATTAAAGTGTTACAGGCATCTACCGTGTGATTAGCGGTGATGCCTGTTTTTAGTTG
GTCATCAGTTGGTTCATCAA

Product: undecaprenyl-phosphate N-acetyl-glucosaminyl transferase

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MIRFEILVSLVATMILSAILTPFVRKLAFKIGAVDKPNVRRVNKIPMPTMGGLAIFISYTVGTTVLYLMHQFPSRIFFAL
LGGELIIIATGVIDDIYELKPRQKMLGITLAALEVYFIGGIRMTTFTFPLLGLIHFQWLSLPVTLLWILAITNAVNLIDG
LDGLATGVSIISLSTMGIIGLFFLNANMFVSLLIFTLVAAMIGFLPYNFFPARIYLGDTGSLFIGFMTAVFSLFGLKNVT
LISVGIPVMILGVPITDTVYAMIRRILNKKPISQADKHHLHHRLMQLGLTHRQTVMVIYGIALIFSFISLLYPISSIWGS
VLLTIGLLFGLELFVEAIGLAGDNRQPLLDWIKRTVARLTSKSNH

Sequences:

>Translated_365_residues
MIRFEILVSLVATMILSAILTPFVRKLAFKIGAVDKPNVRRVNKIPMPTMGGLAIFISYTVGTTVLYLMHQFPSRIFFAL
LGGELIIIATGVIDDIYELKPRQKMLGITLAALEVYFIGGIRMTTFTFPLLGLIHFQWLSLPVTLLWILAITNAVNLIDG
LDGLATGVSIISLSTMGIIGLFFLNANMFVSLLIFTLVAAMIGFLPYNFFPARIYLGDTGSLFIGFMTAVFSLFGLKNVT
LISVGIPVMILGVPITDTVYAMIRRILNKKPISQADKHHLHHRLMQLGLTHRQTVMVIYGIALIFSFISLLYPISSIWGS
VLLTIGLLFGLELFVEAIGLAGDNRQPLLDWIKRTVARLTSKSNH
>Mature_365_residues
MIRFEILVSLVATMILSAILTPFVRKLAFKIGAVDKPNVRRVNKIPMPTMGGLAIFISYTVGTTVLYLMHQFPSRIFFAL
LGGELIIIATGVIDDIYELKPRQKMLGITLAALEVYFIGGIRMTTFTFPLLGLIHFQWLSLPVTLLWILAITNAVNLIDG
LDGLATGVSIISLSTMGIIGLFFLNANMFVSLLIFTLVAAMIGFLPYNFFPARIYLGDTGSLFIGFMTAVFSLFGLKNVT
LISVGIPVMILGVPITDTVYAMIRRILNKKPISQADKHHLHHRLMQLGLTHRQTVMVIYGIALIFSFISLLYPISSIWGS
VLLTIGLLFGLELFVEAIGLAGDNRQPLLDWIKRTVARLTSKSNH

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

Organism=Escherichia coli, GI1790218, Length=287, Percent_Identity=26.8292682926829, Blast_Score=106, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 40376; Mature: 40376

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRFEILVSLVATMILSAILTPFVRKLAFKIGAVDKPNVRRVNKIPMPTMGGLAIFISYT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
VGTTVLYLMHQFPSRIFFALLGGELIIIATGVIDDIYELKPRQKMLGITLAALEVYFIGG
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
IRMTTFTFPLLGLIHFQWLSLPVTLLWILAITNAVNLIDGLDGLATGVSIISLSTMGIIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
LFFLNANMFVSLLIFTLVAAMIGFLPYNFFPARIYLGDTGSLFIGFMTAVFSLFGLKNVT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCE
LISVGIPVMILGVPITDTVYAMIRRILNKKPISQADKHHLHHRLMQLGLTHRQTVMVIYG
EEEECCCEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
IALIFSFISLLYPISSIWGSVLLTIGLLFGLELFVEAIGLAGDNRQPLLDWIKRTVARLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
SKSNH
CCCCC
>Mature Secondary Structure
MIRFEILVSLVATMILSAILTPFVRKLAFKIGAVDKPNVRRVNKIPMPTMGGLAIFISYT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
VGTTVLYLMHQFPSRIFFALLGGELIIIATGVIDDIYELKPRQKMLGITLAALEVYFIGG
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
IRMTTFTFPLLGLIHFQWLSLPVTLLWILAITNAVNLIDGLDGLATGVSIISLSTMGIIG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
LFFLNANMFVSLLIFTLVAAMIGFLPYNFFPARIYLGDTGSLFIGFMTAVFSLFGLKNVT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCCCE
LISVGIPVMILGVPITDTVYAMIRRILNKKPISQADKHHLHHRLMQLGLTHRQTVMVIYG
EEEECCCEEEEECCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
IALIFSFISLLYPISSIWGSVLLTIGLLFGLELFVEAIGLAGDNRQPLLDWIKRTVARLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
SKSNH
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]