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The map label for this gene is panD

Identifier: 28377460

GI number: 28377460

Start: 551916

End: 552308

Strand: Direct

Name: panD

Synonym: lp_0579

Alternate gene names: 28377460

Gene position: 551916-552308 (Clockwise)

Preceding gene: 28377459

Following gene: 28377461

Centisome position: 16.68

GC content: 40.97

Gene sequence:

>393_bases
ATGTTAATTGATATGTTAAAAGGTAAGATTCACCGGGCAACCGTTACACAGGCCGATTTGGAATATGTTGGTAGTATTAC
TATTGATGAAACATTGATGGAAGCAAGTGGAATCTTGGAATACGAAAAAGTTCAAATTGCGGATGTAAATAATGGCGCGC
GGTTTGAAACTTATGTGATTGCGGGGCCAAGGGACTCAGGCGTGATTTGCTTGAACGGTGCTACTGCTCGATGTGCATCA
GTTGGCGATAAGGTTATTATTATGAATTATGCGCAATTTGAGCCAGAAGAGGCCAAGCATGCAAAGCCGTATGTTGTACT
TGTCGACGATGAAAATAGATTGACGAAGCGAGTACGTTATGAAAAGCATGGATTATTAGCAGAAGAACTATGA

Upstream 100 bases:

>100_bases
AGTAAAGTGGAAAAGTTTGCTGGTGTTTATAAAGATGTTTTGAAACAAATGATTGAAAATATAGATGGTGAAATTTAAGT
AGCCGAGGAGGTATAGAGTA

Downstream 100 bases:

>100_bases
AATGGCGAGGGTATCTAACACCTGTAACAGAAAATTATCTGCATGCATACGGGGTAGGCTACATCTCATATGTGCTGGCA
CGTAAGTTTCATGTTGATTC

Product: aspartate alpha-decarboxylase

Products: NA

Alternate protein names: Aspartate alpha-decarboxylase

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MLIDMLKGKIHRATVTQADLEYVGSITIDETLMEASGILEYEKVQIADVNNGARFETYVIAGPRDSGVICLNGATARCAS
VGDKVIIMNYAQFEPEEAKHAKPYVVLVDDENRLTKRVRYEKHGLLAEEL

Sequences:

>Translated_130_residues
MLIDMLKGKIHRATVTQADLEYVGSITIDETLMEASGILEYEKVQIADVNNGARFETYVIAGPRDSGVICLNGATARCAS
VGDKVIIMNYAQFEPEEAKHAKPYVVLVDDENRLTKRVRYEKHGLLAEEL
>Mature_130_residues
MLIDMLKGKIHRATVTQADLEYVGSITIDETLMEASGILEYEKVQIADVNNGARFETYVIAGPRDSGVICLNGATARCAS
VGDKVIIMNYAQFEPEEAKHAKPYVVLVDDENRLTKRVRYEKHGLLAEEL

Specific function: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine

COG id: COG0853

COG function: function code H; Aspartate 1-decarboxylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the panD family

Homologues:

Organism=Escherichia coli, GI1786323, Length=119, Percent_Identity=46.218487394958, Blast_Score=114, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PAND_LACPL (Q88Z02)

Other databases:

- EMBL:   AL935253
- RefSeq:   NP_784352.1
- ProteinModelPortal:   Q88Z02
- SMR:   Q88Z02
- GeneID:   1061538
- GenomeReviews:   AL935263_GR
- KEGG:   lpl:lp_0579
- NMPDR:   fig|220668.1.peg.486
- HOGENOM:   HBG302821
- OMA:   LYSKIHR
- ProtClustDB:   PRK05449
- BioCyc:   LPLA220668:LP_0579-MONOMER
- BRENDA:   4.1.1.11
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00446
- InterPro:   IPR009010
- InterPro:   IPR003190
- Gene3D:   G3DSA:2.40.40.20
- PANTHER:   PTHR21012
- PIRSF:   PIRSF006246
- ProDom:   PD009294
- TIGRFAMs:   TIGR00223

Pfam domain/function: PF02261 Asp_decarbox; SSF50692 Asp_decarb_fold

EC number: =4.1.1.11

Molecular weight: Translated: 14458; Mature: 14458

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00014 ER_TARGET

Important sites: ACT_SITE 25-25 ACT_SITE 58-58 BINDING 57-57

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIDMLKGKIHRATVTQADLEYVGSITIDETLMEASGILEYEKVQIADVNNGARFETYVI
CCCHHCCCCEEEEEECCCCHHHHCCEEHHHHHHHHCCCEEEEEEEEEECCCCCEEEEEEE
AGPRDSGVICLNGATARCASVGDKVIIMNYAQFEPEEAKHAKPYVVLVDDENRLTKRVRY
ECCCCCCEEEECCCCCCHHCCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCHHHHHHHH
EKHGLLAEEL
HHCCCCCCCC
>Mature Secondary Structure
MLIDMLKGKIHRATVTQADLEYVGSITIDETLMEASGILEYEKVQIADVNNGARFETYVI
CCCHHCCCCEEEEEECCCCHHHHCCEEHHHHHHHHCCCEEEEEEEEEECCCCCEEEEEEE
AGPRDSGVICLNGATARCASVGDKVIIMNYAQFEPEEAKHAKPYVVLVDDENRLTKRVRY
ECCCCCCEEEECCCCCCHHCCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCHHHHHHHH
EKHGLLAEEL
HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12566566