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The map label for this gene is glcD [H]

Identifier: 28199140

GI number: 28199140

Start: 1462647

End: 1464035

Strand: Reverse

Name: glcD [H]

Synonym: PD1254

Alternate gene names: 28199140

Gene position: 1464035-1462647 (Counterclockwise)

Preceding gene: 28199147

Following gene: 28199136

Centisome position: 58.1

GC content: 55.8

Gene sequence:

>1389_bases
ATGAATGACTCCCGCCTCACATCCTTGCATCAAACCCTTCCAACGTTGCGTCTCAAGACCGAACCTGCCGACTTACAGCA
CTATGGCCGCGACTGGACCCGGCGCTTCACACCGGCACCCTTAGCAATCGCACTTCCTGCCACTGTCCAAGAAGTCCAGG
CCATTGTGCGTTGGGCCAATGATGCCCACATTGCGATCGTCCCTTCCGGCGGGCGCACCGGCCTATCCGGCGGTGCCATG
GCCACCAATGGCGAACTGGTGCTCAGTCTGGAGCGGATGAACAAAATGCTCCAGTTCGACCCCATGGATCGAACCATGAC
CGTGCAAGCAGGCATGCCATTAGAAGCCGTCCAAGCCGTCGCCCGCCAACACGGCCTCCTGTATCCCGTCGACTTTGCTG
CCCGAGGCTCATGCTCCATTGGCGGCACCATTGCGACCAATGCAGGAGGAATCCGCGTTGTCCGTTACGGCAACACCCGC
GAATGGATCGCTGGCCTCAACGTAGTGACTGGAACTGGCGAACTCCTCGAGTTGAATCATGCCCTGATCAAAAACTCCAG
CGGCTATGACTTTCGACATCTGATGATTGGTTCCGAAGGCACATTGGGCATTGTCGTCGAAGCCACCTTGCGTCTGACCG
ACCCACCGCCACCGACCAAAGTCATGCTGCTGGCATTGCCCACCTTTGACGTCTTGATGCAAGTATTTGCCGCCTTTCGC
GCACAACTACAGATTGAAGCCTTCGAATTTTTTACGCAGCGCGCACTGCCCCATGTTCTAGCCCACGGCGCCCAAGCACC
GTTTGAACATCCCTATCCGTACTACGTCGTCACCGAATTCCCCTGCGCCGACGCAGCCCAAGAAACCACCGCACTCACTG
TCTTTGAAACCTGCATGGAGCAGGGCTGGGTCTTGGATGGTGTCATCAGCCAGAGCGACGCACAGGCGGCCCAACTATGG
CGACTGCGTGAGAGCATCACCGAAAGCATTGCCCCATATACCCCGTATAAAAACGATATTGCCGTGCGCATTGCTGCCAT
GCCCGCATTTCTAGAACAAGCACAAACATTACTGAGCCAAGCCTACCCAGAATTTGAAGTCCTCTGGTTCGGCCATATCG
GTGACGGCAACCTACACATTAACGTCCTCAAACCGCACACAGTGCCCCAGACTGACTTCATCCACACCTGCGAACACGTC
ACCGCACTGCTTGCTGACCTCCTACAACGTTTCCGCGGCAGCATCTCCGCAGAACATGGCATTGGCCTGATAAAAAAGCC
CTACCTTCACAGCACCCGCAGCCCTGCTGAAATTGCATTAATGCGTCAACTAAAACGCGCATTCGACCCAAAATGGATAT
TGAACCCAGGGAAAGTATTTGACCCCTAA

Upstream 100 bases:

>100_bases
TTCCGCTACCATGCTGCACGGGTGCCCCTACCAGTACCTCTAGCAGCCTGCGCCCTCCTCATCTATTGTTCTGCGCTTAT
TGTGTTGCCCCTGTGATCTG

Downstream 100 bases:

>100_bases
ACAGCCCATCCAACACGCCTTGTCCATTGTGCCAAACAACCCAGATCTCCCAATGGGGCGCACCTGACATCCTCACGGCT
GCTATGTGACTCAGACCCTA

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MNDSRLTSLHQTLPTLRLKTEPADLQHYGRDWTRRFTPAPLAIALPATVQEVQAIVRWANDAHIAIVPSGGRTGLSGGAM
ATNGELVLSLERMNKMLQFDPMDRTMTVQAGMPLEAVQAVARQHGLLYPVDFAARGSCSIGGTIATNAGGIRVVRYGNTR
EWIAGLNVVTGTGELLELNHALIKNSSGYDFRHLMIGSEGTLGIVVEATLRLTDPPPPTKVMLLALPTFDVLMQVFAAFR
AQLQIEAFEFFTQRALPHVLAHGAQAPFEHPYPYYVVTEFPCADAAQETTALTVFETCMEQGWVLDGVISQSDAQAAQLW
RLRESITESIAPYTPYKNDIAVRIAAMPAFLEQAQTLLSQAYPEFEVLWFGHIGDGNLHINVLKPHTVPQTDFIHTCEHV
TALLADLLQRFRGSISAEHGIGLIKKPYLHSTRSPAEIALMRQLKRAFDPKWILNPGKVFDP

Sequences:

>Translated_462_residues
MNDSRLTSLHQTLPTLRLKTEPADLQHYGRDWTRRFTPAPLAIALPATVQEVQAIVRWANDAHIAIVPSGGRTGLSGGAM
ATNGELVLSLERMNKMLQFDPMDRTMTVQAGMPLEAVQAVARQHGLLYPVDFAARGSCSIGGTIATNAGGIRVVRYGNTR
EWIAGLNVVTGTGELLELNHALIKNSSGYDFRHLMIGSEGTLGIVVEATLRLTDPPPPTKVMLLALPTFDVLMQVFAAFR
AQLQIEAFEFFTQRALPHVLAHGAQAPFEHPYPYYVVTEFPCADAAQETTALTVFETCMEQGWVLDGVISQSDAQAAQLW
RLRESITESIAPYTPYKNDIAVRIAAMPAFLEQAQTLLSQAYPEFEVLWFGHIGDGNLHINVLKPHTVPQTDFIHTCEHV
TALLADLLQRFRGSISAEHGIGLIKKPYLHSTRSPAEIALMRQLKRAFDPKWILNPGKVFDP
>Mature_462_residues
MNDSRLTSLHQTLPTLRLKTEPADLQHYGRDWTRRFTPAPLAIALPATVQEVQAIVRWANDAHIAIVPSGGRTGLSGGAM
ATNGELVLSLERMNKMLQFDPMDRTMTVQAGMPLEAVQAVARQHGLLYPVDFAARGSCSIGGTIATNAGGIRVVRYGNTR
EWIAGLNVVTGTGELLELNHALIKNSSGYDFRHLMIGSEGTLGIVVEATLRLTDPPPPTKVMLLALPTFDVLMQVFAAFR
AQLQIEAFEFFTQRALPHVLAHGAQAPFEHPYPYYVVTEFPCADAAQETTALTVFETCMEQGWVLDGVISQSDAQAAQLW
RLRESITESIAPYTPYKNDIAVRIAAMPAFLEQAQTLLSQAYPEFEVLWFGHIGDGNLHINVLKPHTVPQTDFIHTCEHV
TALLADLLQRFRGSISAEHGIGLIKKPYLHSTRSPAEIALMRQLKRAFDPKWILNPGKVFDP

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI119964728, Length=447, Percent_Identity=34.4519015659955, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI37595756, Length=446, Percent_Identity=28.0269058295964, Blast_Score=163, Evalue=4e-40,
Organism=Homo sapiens, GI37595754, Length=469, Percent_Identity=27.0788912579957, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI4501993, Length=475, Percent_Identity=23.3684210526316, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1789351, Length=467, Percent_Identity=28.9079229122056, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI48994907, Length=502, Percent_Identity=21.1155378486056, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI48994914, Length=158, Percent_Identity=27.8481012658228, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17534361, Length=450, Percent_Identity=30.4444444444444, Blast_Score=229, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI71992373, Length=475, Percent_Identity=26.7368421052632, Blast_Score=169, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI71992381, Length=475, Percent_Identity=25.2631578947368, Blast_Score=148, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI71992392, Length=395, Percent_Identity=26.0759493670886, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17556096, Length=201, Percent_Identity=25.8706467661692, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320023, Length=455, Percent_Identity=34.7252747252747, Blast_Score=298, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6320764, Length=458, Percent_Identity=31.0043668122271, Blast_Score=261, Evalue=1e-70,
Organism=Saccharomyces cerevisiae, GI6320027, Length=446, Percent_Identity=27.8026905829596, Blast_Score=162, Evalue=8e-41,
Organism=Drosophila melanogaster, GI18921117, Length=476, Percent_Identity=32.3529411764706, Blast_Score=265, Evalue=6e-71,
Organism=Drosophila melanogaster, GI24639277, Length=476, Percent_Identity=32.3529411764706, Blast_Score=265, Evalue=6e-71,
Organism=Drosophila melanogaster, GI24639275, Length=476, Percent_Identity=32.3529411764706, Blast_Score=265, Evalue=6e-71,
Organism=Drosophila melanogaster, GI24653753, Length=218, Percent_Identity=29.8165137614679, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 50948; Mature: 50948

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDSRLTSLHQTLPTLRLKTEPADLQHYGRDWTRRFTPAPLAIALPATVQEVQAIVRWAN
CCCHHHHHHHHHCCCEEEECCCHHHHHHCCHHHHCCCCCCEEEECCHHHHHHHHHHHHCC
DAHIAIVPSGGRTGLSGGAMATNGELVLSLERMNKMLQFDPMDRTMTVQAGMPLEAVQAV
CCEEEEEECCCCCCCCCCCEEECCCEEEEHHHHHHHHCCCCCCCEEEEECCCCHHHHHHH
ARQHGLLYPVDFAARGSCSIGGTIATNAGGIRVVRYGNTREWIAGLNVVTGTGELLELNH
HHHCCCEEEECCCCCCCCCCCCEEEECCCCEEEEEECCCHHHHHCCEEEECCCHHHHHHH
ALIKNSSGYDFRHLMIGSEGTLGIVVEATLRLTDPPPPTKVMLLALPTFDVLMQVFAAFR
HHHCCCCCCCEEEEEECCCCCEEEEEEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHH
AQLQIEAFEFFTQRALPHVLAHGAQAPFEHPYPYYVVTEFPCADAAQETTALTVFETCME
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
QGWVLDGVISQSDAQAAQLWRLRESITESIAPYTPYKNDIAVRIAAMPAFLEQAQTLLSQ
CCCEEEHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHH
AYPEFEVLWFGHIGDGNLHINVLKPHTVPQTDFIHTCEHVTALLADLLQRFRGSISAEHG
CCCCEEEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IGLIKKPYLHSTRSPAEIALMRQLKRAFDPKWILNPGKVFDP
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCC
>Mature Secondary Structure
MNDSRLTSLHQTLPTLRLKTEPADLQHYGRDWTRRFTPAPLAIALPATVQEVQAIVRWAN
CCCHHHHHHHHHCCCEEEECCCHHHHHHCCHHHHCCCCCCEEEECCHHHHHHHHHHHHCC
DAHIAIVPSGGRTGLSGGAMATNGELVLSLERMNKMLQFDPMDRTMTVQAGMPLEAVQAV
CCEEEEEECCCCCCCCCCCEEECCCEEEEHHHHHHHHCCCCCCCEEEEECCCCHHHHHHH
ARQHGLLYPVDFAARGSCSIGGTIATNAGGIRVVRYGNTREWIAGLNVVTGTGELLELNH
HHHCCCEEEECCCCCCCCCCCCEEEECCCCEEEEEECCCHHHHHCCEEEECCCHHHHHHH
ALIKNSSGYDFRHLMIGSEGTLGIVVEATLRLTDPPPPTKVMLLALPTFDVLMQVFAAFR
HHHCCCCCCCEEEEEECCCCCEEEEEEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHH
AQLQIEAFEFFTQRALPHVLAHGAQAPFEHPYPYYVVTEFPCADAAQETTALTVFETCME
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
QGWVLDGVISQSDAQAAQLWRLRESITESIAPYTPYKNDIAVRIAAMPAFLEQAQTLLSQ
CCCEEEHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHH
AYPEFEVLWFGHIGDGNLHINVLKPHTVPQTDFIHTCEHVTALLADLLQRFRGSISAEHG
CCCCEEEEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
IGLIKKPYLHSTRSPAEIALMRQLKRAFDPKWILNPGKVFDP
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]