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The map label for this gene is kdkA [H]

Identifier: 28199100

GI number: 28199100

Start: 1414311

End: 1415090

Strand: Reverse

Name: kdkA [H]

Synonym: PD1213

Alternate gene names: 28199100

Gene position: 1415090-1414311 (Counterclockwise)

Preceding gene: 28199102

Following gene: 28199087

Centisome position: 56.16

GC content: 53.21

Gene sequence:

>780_bases
TTGCTCCATCGTATTGTTACACTTGAACGCATGGTTGCATTTGACGCCAACGAAATCCTGACGCCATTCTGCGAGGGTCA
CAGGGAAGGAGCTATTTTGTTCGATTGCCAGCGTATGCGGCAAGTCGAGTATGGTCTATTTGTGCCTGCTTGGTGGGGGG
AGCGAGCCCATCCGATATCTGAGGGAGGACGTGGTAGTGCTTGGTTCGTGGAGGCGTCGTTTGGGAATGCGGTATTGCGT
CAGTACCGACGTGGCGGAATGATCGCTATGCTTAATCGTGATCGTTACTTCTGGTGTGGTGGTCACCGTACTCGAAGTGT
CCTTGAGTTCCGCTTGATGCGTGAGTTGATCTCGCGAGGGTTGCCGGTTCCAACTCCCTTGGCTGCTTGTTACGTGCGGC
ATGGTGTGCAATATCGAGCAGCGATCTTGATGGAGCGACTGGAGGGAGTGTCTTCGCTTGCTATGTGCGTACGTGGGAAC
AGCAAAGAGATACATTGGGAGCAGATTGGGCGGATGATTTCGCGCTTTCATCGCGAGGGGCTGGACCATGCGGATCTTAA
TGCTCACAACATTCTGTTAGACCAAGCTGGCCAGTGCTGGTTGATTGATTTCGATCGTGGTGCGCTACGTATTCCTGCGA
CCAAGTGGCGAGAGCACAATTTAGCCCGCTTACTGCGCTCATTGCTGAAAATACGGGGGGAACGTAGTGTGGATGCAGTG
TATAGGGACTTTGAGCGTTTGTGTCGTGCTTATGACTTGGCTTGGGGTCGGGGGTGTTGA

Upstream 100 bases:

>100_bases
GTGCTTGGGGTCGTTCGCGTTGCAGGGTACGCACCAGCGGTAACACGTGAGTGATGTCTCCAAGTGCTGATAAGCGTAAC
AGGCATAGAGAATAGGGTCT

Downstream 100 bases:

>100_bases
TGTTTTGTGATATCTGGGTGCACTGCCTCTCACTGTGGAGTTGGGTTACTCGCAGGTACGGATGAACTCGTGTTTGATGC
GTGTGGTCAGGCTCAGTATG

Product: 3-deoxy-D-manno-octulosonic-acid kinase

Products: NA

Alternate protein names: KDO kinase [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MLHRIVTLERMVAFDANEILTPFCEGHREGAILFDCQRMRQVEYGLFVPAWWGERAHPISEGGRGSAWFVEASFGNAVLR
QYRRGGMIAMLNRDRYFWCGGHRTRSVLEFRLMRELISRGLPVPTPLAACYVRHGVQYRAAILMERLEGVSSLAMCVRGN
SKEIHWEQIGRMISRFHREGLDHADLNAHNILLDQAGQCWLIDFDRGALRIPATKWREHNLARLLRSLLKIRGERSVDAV
YRDFERLCRAYDLAWGRGC

Sequences:

>Translated_259_residues
MLHRIVTLERMVAFDANEILTPFCEGHREGAILFDCQRMRQVEYGLFVPAWWGERAHPISEGGRGSAWFVEASFGNAVLR
QYRRGGMIAMLNRDRYFWCGGHRTRSVLEFRLMRELISRGLPVPTPLAACYVRHGVQYRAAILMERLEGVSSLAMCVRGN
SKEIHWEQIGRMISRFHREGLDHADLNAHNILLDQAGQCWLIDFDRGALRIPATKWREHNLARLLRSLLKIRGERSVDAV
YRDFERLCRAYDLAWGRGC
>Mature_259_residues
MLHRIVTLERMVAFDANEILTPFCEGHREGAILFDCQRMRQVEYGLFVPAWWGERAHPISEGGRGSAWFVEASFGNAVLR
QYRRGGMIAMLNRDRYFWCGGHRTRSVLEFRLMRELISRGLPVPTPLAACYVRHGVQYRAAILMERLEGVSSLAMCVRGN
SKEIHWEQIGRMISRFHREGLDHADLNAHNILLDQAGQCWLIDFDRGALRIPATKWREHNLARLLRSLLKIRGERSVDAV
YRDFERLCRAYDLAWGRGC

Specific function: ATP-dependent phosphorylation of 3-deoxy-D-manno- octulosonic acid at the 4-OH position [H]

COG id: COG0515

COG function: function code RTKL; Serine/threonine protein kinase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. KdkA/rfaP family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022826
- InterPro:   IPR011009
- InterPro:   IPR010440 [H]

Pfam domain/function: PF06293 Kdo [H]

EC number: NA

Molecular weight: Translated: 30014; Mature: 30014

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHRIVTLERMVAFDANEILTPFCEGHREGAILFDCQRMRQVEYGLFVPAWWGERAHPIS
CCCHHHHHHHHHHHCHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCEEEECCCCCCCCCCC
EGGRGSAWFVEASFGNAVLRQYRRGGMIAMLNRDRYFWCGGHRTRSVLEFRLMRELISRG
CCCCCCEEEEEECCCHHHHHHHHCCCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHCC
LPVPTPLAACYVRHGVQYRAAILMERLEGVSSLAMCVRGNSKEIHWEQIGRMISRFHREG
CCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHCC
LDHADLNAHNILLDQAGQCWLIDFDRGALRIPATKWREHNLARLLRSLLKIRGERSVDAV
CCCCCCCHHHEEEECCCCEEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
YRDFERLCRAYDLAWGRGC
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLHRIVTLERMVAFDANEILTPFCEGHREGAILFDCQRMRQVEYGLFVPAWWGERAHPIS
CCCHHHHHHHHHHHCHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCEEEECCCCCCCCCCC
EGGRGSAWFVEASFGNAVLRQYRRGGMIAMLNRDRYFWCGGHRTRSVLEFRLMRELISRG
CCCCCCEEEEEECCCHHHHHHHHCCCEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHCC
LPVPTPLAACYVRHGVQYRAAILMERLEGVSSLAMCVRGNSKEIHWEQIGRMISRFHREG
CCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHCC
LDHADLNAHNILLDQAGQCWLIDFDRGALRIPATKWREHNLARLLRSLLKIRGERSVDAV
CCCCCCCHHHEEEECCCCEEEEEECCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHH
YRDFERLCRAYDLAWGRGC
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA