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The map label for this gene is frnE

Identifier: 28199087

GI number: 28199087

Start: 1397400

End: 1398068

Strand: Reverse

Name: frnE

Synonym: PD1199

Alternate gene names: NA

Gene position: 1398068-1397400 (Counterclockwise)

Preceding gene: 28199100

Following gene: 28199085

Centisome position: 55.48

GC content: 51.27

Gene sequence:

>669_bases
ATGTCGAGTCCTGTTGTGGAGATCCAGATATGGTCGGATCTGATCTGTCCTTGGTGCTGGATTGGCAAGCGGCGTTTGGA
GCGCGCCCTCCGCAATTCATCATTGTTTGCCGACATCAAAGTACGTCACCGCGCATTCCGATTAATGCCGGAACTGATTC
CCCTTCCAGTGATTGACGTACTCCAGCAGCGTTATGGTGGTTCCGCCGAACAGATTGTGGCAATACAGCAACGTATTGAG
AAAATTGCTGCCGAAGAAAGCTTAATATATCGATTGGTTGGTACTCAGGGCGCAGATACCCTGCAGGCACACCGCTTGTT
GTATTTGGCGCACCGCCAGGGATTGCAAGAAGTCCTTTTGGAGCGCTTTTACAGCGCTTATTTCAGCGAAGGAACTCCCA
TATTTGATACTGATACTTTGGCGCCTTTAGCGCTTGACGTGGGATTGGAGCGCACAGCAGTTGCCGCATTATTTGCTGGT
CAAGATTTTATCGCTGAGATAGAGGATGATCAGCGCCGCTTGCAGCGTTACGGTGCAAACGGTGTCCCATTTTTCCTGAT
GGATGGGCGTATTGCAGTGAATGGTGCCCAGCCAATAGAGGCGTTCTCAGATGCACTGGCCCAGTTGAATGCCGATGCGG
CATCGCAATCGGCATTCTTCCTGCGTTGA

Upstream 100 bases:

>100_bases
CCGTACGTATCCTTTACAGACTATCCTCGCGATCTGGAGATGGCATGTCCCTGATTGGATCGTGTCTACTTCTCTACTGA
TATTTTTAAGGAATGTCGCA

Downstream 100 bases:

>100_bases
TGACTGCAACGCGATGCGATACCTAAGCAGAGCATCACGCGTTTTGAAGATGCACCTGATTCCCGTCAAGCAGCGTCTGG
CCGCGGCGCTTACCAACTGT

Product: polyketide synthase

Products: NA

Alternate protein names: Dsba Oxidoreductase; Dithiol-Disulfide Isomerase; FrnE Protein; Protein Dithiol-Disulfide Isomerase; Protein-Disulfide Isomerase; Polyketide Biosynthesis Associated Protein; Polyketide Synthase; DSBA-Like Thioredoxin Domain-Containing Protein; Thiol Oxidoreductase FrnE; Oxidoreductase; DsbA Oxidoreductase; Thioredoxin Domain Protein DsbA Family; Thioredoxin Domain-Containing Protein; Isomerase; DSBA-Like Thioredoxin Domain; Dsb Family Thioredoxin Protein; Protein Disulfide-Isomerase; Protein Disulfide Isomerase; Peptidoglycan Hydrolase; Dsba Oxidoreductase Family Protein; 2-Hydroxychromene-2-Carboxylateisomerase Family Protein; Dithiol-Disulfide Isomerase Protein; 2-Hydroxychromene-2-Carboxylate Isomerase Family Protein; Polyketide Biosynthesis Dithiol-Disulfide Isomerase; Disulfide Isomerase; DSBA-Like Thioredoxin Family Protein; Protein-Disulfide Isomerase DsbC/DsbG; Thiol Oxidoreductase; DsbA Family Oxidoreductase

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MSSPVVEIQIWSDLICPWCWIGKRRLERALRNSSLFADIKVRHRAFRLMPELIPLPVIDVLQQRYGGSAEQIVAIQQRIE
KIAAEESLIYRLVGTQGADTLQAHRLLYLAHRQGLQEVLLERFYSAYFSEGTPIFDTDTLAPLALDVGLERTAVAALFAG
QDFIAEIEDDQRRLQRYGANGVPFFLMDGRIAVNGAQPIEAFSDALAQLNADAASQSAFFLR

Sequences:

>Translated_222_residues
MSSPVVEIQIWSDLICPWCWIGKRRLERALRNSSLFADIKVRHRAFRLMPELIPLPVIDVLQQRYGGSAEQIVAIQQRIE
KIAAEESLIYRLVGTQGADTLQAHRLLYLAHRQGLQEVLLERFYSAYFSEGTPIFDTDTLAPLALDVGLERTAVAALFAG
QDFIAEIEDDQRRLQRYGANGVPFFLMDGRIAVNGAQPIEAFSDALAQLNADAASQSAFFLR
>Mature_221_residues
SSPVVEIQIWSDLICPWCWIGKRRLERALRNSSLFADIKVRHRAFRLMPELIPLPVIDVLQQRYGGSAEQIVAIQQRIEK
IAAEESLIYRLVGTQGADTLQAHRLLYLAHRQGLQEVLLERFYSAYFSEGTPIFDTDTLAPLALDVGLERTAVAALFAGQ
DFIAEIEDDQRRLQRYGANGVPFFLMDGRIAVNGAQPIEAFSDALAQLNADAASQSAFFLR

Specific function: Unknown

COG id: COG2761

COG function: function code Q; Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 24922; Mature: 24791

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPVVEIQIWSDLICPWCWIGKRRLERALRNSSLFADIKVRHRAFRLMPELIPLPVIDV
CCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
LQQRYGGSAEQIVAIQQRIEKIAAEESLIYRLVGTQGADTLQAHRLLYLAHRQGLQEVLL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
ERFYSAYFSEGTPIFDTDTLAPLALDVGLERTAVAALFAGQDFIAEIEDDQRRLQRYGAN
HHHHHHHHCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
GVPFFLMDGRIAVNGAQPIEAFSDALAQLNADAASQSAFFLR
CCEEEEECCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SSPVVEIQIWSDLICPWCWIGKRRLERALRNSSLFADIKVRHRAFRLMPELIPLPVIDV
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
LQQRYGGSAEQIVAIQQRIEKIAAEESLIYRLVGTQGADTLQAHRLLYLAHRQGLQEVLL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
ERFYSAYFSEGTPIFDTDTLAPLALDVGLERTAVAALFAGQDFIAEIEDDQRRLQRYGAN
HHHHHHHHCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
GVPFFLMDGRIAVNGAQPIEAFSDALAQLNADAASQSAFFLR
CCEEEEECCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA