Click here to switch to the map view.

The map label for this gene is algR [H]

Identifier: 28199045

GI number: 28199045

Start: 1350700

End: 1351458

Strand: Reverse

Name: algR [H]

Synonym: PD1153

Alternate gene names: 28199045

Gene position: 1351458-1350700 (Counterclockwise)

Preceding gene: 28199046

Following gene: 28199044

Centisome position: 53.63

GC content: 49.8

Gene sequence:

>759_bases
TTGCTGCGTATATTGATTGCCGATGATGAGCCGCTTGCGCGTGAGCGGCTGCGTGTGTTGCTGCAAGCACAAATGCAACA
TTTAGAGGTTGTGGCTGAGGCTGAAAATGGCGAGCAGGTATTACATGATTGTCAGCGTCTGAATCCTGATTTGGTCCTGA
TGGACATTGCTATGCCTGGCATTGATGGTTTGGAAACAGCACGTTATTTACGTTATTTACCTGCTTGTCCAGCGGTTGTG
TTTTGCACTGCTTATGGTGATCACGCATTGTCGGCATTTGATGTGGAGGCGATTGATTACCTGATGAAGCCAGTGCGTGC
GGAACGGCTTCATGCGGCATTGAAACGAGTGCAAACCTTCGTGGCTGGACGTTTACGTGAACCCCAGACCTCGTGTGATG
AGACACCACGTACTCATTTGTGCGTGCGTATCCGCGGCGGATTGCGATTGATTCCTTTGGATCAGGTGCGTTATCTACAA
GCAGATGAGAAGTACGTTGTGATCTGTCACGAGCAGGGGGAGGATTTGATTGAGGAATCGTTGAAATCGTTGGAAAAGGA
GTTTAGTGACAGGTTTGTACGTATACATCGCAATTGTTTGATTGCGCGTGCCGAACTGACCGAGTTGCGTCGTTGTAGCG
ATGGACAGGTACAGGCAGTGCTTCGCAATGTTGTTACACCGTTAGCCGTGAGTCGGCGTTGTGTCCCTTTGCTGTGTGAT
CAGTTGCGTCTGTCGGCTGTTTTGACAGGTCGCTGGTAA

Upstream 100 bases:

>100_bases
GGTCCTGATGCTCGAATGACGGGGTTTTGGAGTGGAGGTTACTATTCCTGCGATATCGTATTGCCGTTGATATGATAGGG
TTGATTGGGAGGTTTTCAGT

Downstream 100 bases:

>100_bases
TACCACGATGCCTTTACTTCGTATTGCTACTCGCAAAAGTTTACTTGCTATGTGGCAAAGCGAGTATGTCGCTGCGCGTT
TACGTATGCTGTGCCCTGAT

Product: two-component system, regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MLRILIADDEPLARERLRVLLQAQMQHLEVVAEAENGEQVLHDCQRLNPDLVLMDIAMPGIDGLETARYLRYLPACPAVV
FCTAYGDHALSAFDVEAIDYLMKPVRAERLHAALKRVQTFVAGRLREPQTSCDETPRTHLCVRIRGGLRLIPLDQVRYLQ
ADEKYVVICHEQGEDLIEESLKSLEKEFSDRFVRIHRNCLIARAELTELRRCSDGQVQAVLRNVVTPLAVSRRCVPLLCD
QLRLSAVLTGRW

Sequences:

>Translated_252_residues
MLRILIADDEPLARERLRVLLQAQMQHLEVVAEAENGEQVLHDCQRLNPDLVLMDIAMPGIDGLETARYLRYLPACPAVV
FCTAYGDHALSAFDVEAIDYLMKPVRAERLHAALKRVQTFVAGRLREPQTSCDETPRTHLCVRIRGGLRLIPLDQVRYLQ
ADEKYVVICHEQGEDLIEESLKSLEKEFSDRFVRIHRNCLIARAELTELRRCSDGQVQAVLRNVVTPLAVSRRCVPLLCD
QLRLSAVLTGRW
>Mature_252_residues
MLRILIADDEPLARERLRVLLQAQMQHLEVVAEAENGEQVLHDCQRLNPDLVLMDIAMPGIDGLETARYLRYLPACPAVV
FCTAYGDHALSAFDVEAIDYLMKPVRAERLHAALKRVQTFVAGRLREPQTSCDETPRTHLCVRIRGGLRLIPLDQVRYLQ
ADEKYVVICHEQGEDLIEESLKSLEKEFSDRFVRIHRNCLIARAELTELRRCSDGQVQAVLRNVVTPLAVSRRCVPLLCD
QLRLSAVLTGRW

Specific function: Positive regulator of the algD gene, which codes for a GDP-mannose dehydrogenase, a key step enzyme in the alginate biosynthesis pathway [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082052, Length=253, Percent_Identity=34.3873517786561, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788724, Length=242, Percent_Identity=25.6198347107438, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1788222, Length=127, Percent_Identity=31.496062992126, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=35.3448275862069, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 28719; Mature: 28719

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRILIADDEPLARERLRVLLQAQMQHLEVVAEAENGEQVLHDCQRLNPDLVLMDIAMPG
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEECCCC
IDGLETARYLRYLPACPAVVFCTAYGDHALSAFDVEAIDYLMKPVRAERLHAALKRVQTF
CCHHHHHHHHHHCCCCCHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGRLREPQTSCDETPRTHLCVRIRGGLRLIPLDQVRYLQADEKYVVICHEQGEDLIEES
HHHHCCCCCCCCCCCCCCEEEEEEECCEEEEEHHHHHHHCCCCCEEEEEECCCHHHHHHH
LKSLEKEFSDRFVRIHRNCLIARAELTELRRCSDGQVQAVLRNVVTPLAVSRRCVPLLCD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHH
QLRLSAVLTGRW
HHHHHHHHCCCC
>Mature Secondary Structure
MLRILIADDEPLARERLRVLLQAQMQHLEVVAEAENGEQVLHDCQRLNPDLVLMDIAMPG
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEECCCC
IDGLETARYLRYLPACPAVVFCTAYGDHALSAFDVEAIDYLMKPVRAERLHAALKRVQTF
CCHHHHHHHHHHCCCCCHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGRLREPQTSCDETPRTHLCVRIRGGLRLIPLDQVRYLQADEKYVVICHEQGEDLIEES
HHHHCCCCCCCCCCCCCCEEEEEEECCEEEEEHHHHHHHCCCCCEEEEEECCCHHHHHHH
LKSLEKEFSDRFVRIHRNCLIARAELTELRRCSDGQVQAVLRNVVTPLAVSRRCVPLLCD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHH
QLRLSAVLTGRW
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2493441; 10984043; 2544550; 8159168 [H]