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The map label for this gene is glmU [H]

Identifier: 62185576

GI number: 62185576

Start: 1140685

End: 1141299

Strand: Direct

Name: glmU [H]

Synonym: CAB978

Alternate gene names: 62185576

Gene position: 1140685-1141299 (Clockwise)

Preceding gene: 62185575

Following gene: 62185577

Centisome position: 99.68

GC content: 39.51

Gene sequence:

>615_bases
ATGATACTCGCATCTGTTTTATTCTCTCCTGAAGATTTTTCTTTTCCTGAACTCATTACAGAAGCGTATTATACTTGGGA
TATTTTAGCATTAATAGATAAAAAATTATCCTCTCATGTGTTCTCAGGAATTCAGGGAACTGTAGAATCTGGAGCTTTTT
TAAAAAATATAGAAAGCATAGAAATCGCTGAAGGAGCTTATGTAGAATCTGGAGCCTATATTGTAGGTCCTTGCATCATA
GGTCCCCAAACAGAAGTCCGTCACGGAGCTTATCTACGAGGAAGTGTGATTACAGGTACAGGTTGTGTTATTGGACACTG
TACAGAAGTAAAAAAAGCCTATTTGGGTCATTATGCCAAAGCTGGCCACTTCGCTTATATTGGAGATTCCGTATTAAGTT
CTGAAGTCAATCTCGGTGCAGGTGTGCGTTGTGCCAATTTTCGCCTTGATGGGAAAAATATTTCTGTTCATTGTGCTGAA
GGTCGGGTAGATACCCAACTAAGAAAAGTCGGTGCCTTTCTTGGGAAAAACGTTTCTGTAGGTTGCAATACTGTGATTAA
TCCTGGGCAGTGCATTCCAGCCCATACAAAAATTTATCCCGGAAAAGTTATCTAG

Upstream 100 bases:

>100_bases
AAGAAGAATCTTCGTCTCCCTATGCTTCGAATAGCTTTTGATTACTCCTTGTCACTAAATCGTCATAACTAGACAATATC
CTAAAAAGCTATGACCTGCC

Downstream 100 bases:

>100_bases
GTTTAGGGCAAATTCTATGGTCGTTATGGATATTTTCGAAGCTTACCGCGTAATGATAGAAACTGGGATAGAAAATTCTT
TAGATGAGTTTGGTCCTAAA

Product: putative glucosamine-1-phosphate N-acetyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MILASVLFSPEDFSFPELITEAYYTWDILALIDKKLSSHVFSGIQGTVESGAFLKNIESIEIAEGAYVESGAYIVGPCII
GPQTEVRHGAYLRGSVITGTGCVIGHCTEVKKAYLGHYAKAGHFAYIGDSVLSSEVNLGAGVRCANFRLDGKNISVHCAE
GRVDTQLRKVGAFLGKNVSVGCNTVINPGQCIPAHTKIYPGKVI

Sequences:

>Translated_204_residues
MILASVLFSPEDFSFPELITEAYYTWDILALIDKKLSSHVFSGIQGTVESGAFLKNIESIEIAEGAYVESGAYIVGPCII
GPQTEVRHGAYLRGSVITGTGCVIGHCTEVKKAYLGHYAKAGHFAYIGDSVLSSEVNLGAGVRCANFRLDGKNISVHCAE
GRVDTQLRKVGAFLGKNVSVGCNTVINPGQCIPAHTKIYPGKVI
>Mature_204_residues
MILASVLFSPEDFSFPELITEAYYTWDILALIDKKLSSHVFSGIQGTVESGAFLKNIESIEIAEGAYVESGAYIVGPCII
GPQTEVRHGAYLRGSVITGTGCVIGHCTEVKKAYLGHYAKAGHFAYIGDSVLSSEVNLGAGVRCANFRLDGKNISVHCAE
GRVDTQLRKVGAFLGKNVSVGCNTVINPGQCIPAHTKIYPGKVI

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetyl-glucosamine (UDP- GlcNAc). Responsible for the acetylation of GlcN-1-P to GlcNAc-1- P, and for the uridyl transfer from UTP to GlcNAc-1-P, to produce UDP-GlcN

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 21754; Mature: 21754

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILASVLFSPEDFSFPELITEAYYTWDILALIDKKLSSHVFSGIQGTVESGAFLKNIESI
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHCCCEE
EIAEGAYVESGAYIVGPCIIGPQTEVRHGAYLRGSVITGTGCVIGHCTEVKKAYLGHYAK
EECCCCEEECCCEEEEEEEECCCCCCCCCCEEECEEEECCCEEEECHHHHHHHHHHHHHC
AGHFAYIGDSVLSSEVNLGAGVRCANFRLDGKNISVHCAEGRVDTQLRKVGAFLGKNVSV
CCCEEEECHHHHHCCCCCCCCEEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCCC
GCNTVINPGQCIPAHTKIYPGKVI
CCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MILASVLFSPEDFSFPELITEAYYTWDILALIDKKLSSHVFSGIQGTVESGAFLKNIESI
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHCCCEE
EIAEGAYVESGAYIVGPCIIGPQTEVRHGAYLRGSVITGTGCVIGHCTEVKKAYLGHYAK
EECCCCEEECCCEEEEEEEECCCCCCCCCCEEECEEEECCCEEEECHHHHHHHHHHHHHC
AGHFAYIGDSVLSSEVNLGAGVRCANFRLDGKNISVHCAEGRVDTQLRKVGAFLGKNVSV
CCCEEEECHHHHHCCCCCCCCEEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHCCCCCC
GCNTVINPGQCIPAHTKIYPGKVI
CCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]