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The map label for this gene is uvrD [H]

Identifier: 62185554

GI number: 62185554

Start: 1114273

End: 1116186

Strand: Direct

Name: uvrD [H]

Synonym: CAB955

Alternate gene names: 62185554

Gene position: 1114273-1116186 (Clockwise)

Preceding gene: 62185551

Following gene: 62185555

Centisome position: 97.37

GC content: 39.13

Gene sequence:

>1914_bases
ATGCTTACTTCAGAATTAAACGAAGCACAAATCGCCGCAGTAACTTCACCACTCAGTCCGATTTTAGTTCTCGCTGGAGC
CGGAGCAGGAAAAACTCGTGTAGTCACTTGCCGCATCCTTCATCTCATTAACGAAGGTATCGCCCCTAAAGAAATCCTGG
CAGTAACTTTTACCAATAAAGCAGCGAAAGAACTTAAAGAACGTATTTTACATTTATGCCCTCAAGCGCATGGTTCCGAC
ATTCCTATGGTATGCACATTCCACAGCTTAGGGGTGTTTATTTTACGCAGGTCTATACAAGCATTAAATAGAGAAAATAA
CTTTATTATCTATGATCAAAGTGACACGGACAAACTGCTCAAACAATGCTTACAAAAATTTAATTTAAAGAAAACTCTAA
GCAGTTCCATACAATATCATATATCACAAGCAAAAAACCGTTTGCTTTCCCCTGAGGACTTGGATCCCGAAGAATATATC
GATCCCGTGGTGTCTATTTATAAAGAATACCAACAACGTTTACACGAAGCCAACGCTTTAGATTTTGATGATTTGTTATT
TCTTACCGTCAGACTATTTCAAGAATTTCCTGAGGTTAGAAAAGAATACAGCGAATTATGGAAAGCTCTTTTAATTGACG
AGTATCAGGATACCAACCACGCACAATACAAAATGGCTCAGACGATCGCGGGGAAACATCAAAATATATTTGCTGTGGGA
GATCCCGACCAATCTATTTACTCTTGGCGTGGGGCCAATATTCATAATATTTTAAACTTTGAAAAAGATTATCCTCGAGC
TCTTGTTCTTCGCTTAGAAGATAACTACCGCAGTTACGGAAATATTCTGAATGCTGCCAATGCTCTAATTCAAAACAACG
CTTCACGATTGAAGAAAGACCTCCGCAGCGTAAAAGGCCCGGGAGAAAAAATCCGTGTATTCTTGGGCAAAACAGATAAA
GAAGAAGCCGAATTTGTAGCTGATGAAATCAGCCGTCTACATAGAAGGTCCCAGATTCCCCTTAGCGATATCTGCATTTT
TTATAGGACAAACTTCCAATCTAGAACTTTCGAAGATGCTTTATTACGTAGACGCATTCCCTATGAAATTCTTGGTGGTC
TTTCATTTTATAAACGTAAGGAAATTCAAGATATCTTGGCTTTTTTAAGAATGTTCACTGCGAAATCCGACGTGGTTGCT
TTTGATAGAACAGTCAATCTTCCTAAGAGAGGGCTAGGTCCTTCTACGATTTCCTCTTTAATTGAGTATGCTCTCACAAA
TAACTTGCCGATTTTAGAAGCATGTAACAACGTTTTACAAACTCAAGAGGTGAAACTCTCTAAGAAACAACAAGAAGGCT
TGAGAGAGTATCTCAGTATTTTTCAACAACTCGAACATGCTTATGCAACCCTTCCTCTGAATGAGTTTGTTGTCGCTACA
ATACGCATCACGGGATATTTTCAAGTATTAAAGGAAGATCCTGATACTTTCGAAGATCGGAAAAGCAATCTTGACGAACT
CGCGTCAAAAACTTTCGAGTGGGAACAGCAAAATACAGATGGAACCTTAGAAAACTTCCTAGACGATCTTGCTTTAAAAA
GTTCTACAGATGACACCGAACTGATCGCAGATCGTGTAAATCTCATGACAATTCACAATGGTAAGGGTTTAGAATTCCGC
ATAGCTTTTGTTGTTGGCTTAGAAGAGAACCTTTTCCCCCATGCAAACTCTAAAAGTAGTTATGAAAATCTTGAAGAAGA
ACGACGTCTATGTTACGTAGGAATCACTAGAGCCCAAGATCTCCTTTACTTAACAGCAGCGCAAACTCGTTTTCTTTGGG
GCACAGTGCGTGTCATGAAACCGAGTCGTTTTCTTAAGGAAATCCCTAGAGATTACTTGATTCAAGTACATTAG

Upstream 100 bases:

>100_bases
TTATTATTTGAAAATAAAAGTATATTAACCTTCTTAGATTATTTTAGCTTCAGGGATCCTGATTTTTTTCAGTCAGAAGC
TATTGAATTAGGATACCACT

Downstream 100 bases:

>100_bases
GTATGCTTCAACACCATCAAAAGCTTTCTCTTCACTACCTTCCCTCGCTGCGTATGCAGCAGGGATTGCAAATATTACAA
TCTCCGATTACCGAGCTCTC

Product: DNA helicase II, UvrD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 637; Mature: 637

Protein sequence:

>637_residues
MLTSELNEAQIAAVTSPLSPILVLAGAGAGKTRVVTCRILHLINEGIAPKEILAVTFTNKAAKELKERILHLCPQAHGSD
IPMVCTFHSLGVFILRRSIQALNRENNFIIYDQSDTDKLLKQCLQKFNLKKTLSSSIQYHISQAKNRLLSPEDLDPEEYI
DPVVSIYKEYQQRLHEANALDFDDLLFLTVRLFQEFPEVRKEYSELWKALLIDEYQDTNHAQYKMAQTIAGKHQNIFAVG
DPDQSIYSWRGANIHNILNFEKDYPRALVLRLEDNYRSYGNILNAANALIQNNASRLKKDLRSVKGPGEKIRVFLGKTDK
EEAEFVADEISRLHRRSQIPLSDICIFYRTNFQSRTFEDALLRRRIPYEILGGLSFYKRKEIQDILAFLRMFTAKSDVVA
FDRTVNLPKRGLGPSTISSLIEYALTNNLPILEACNNVLQTQEVKLSKKQQEGLREYLSIFQQLEHAYATLPLNEFVVAT
IRITGYFQVLKEDPDTFEDRKSNLDELASKTFEWEQQNTDGTLENFLDDLALKSSTDDTELIADRVNLMTIHNGKGLEFR
IAFVVGLEENLFPHANSKSSYENLEEERRLCYVGITRAQDLLYLTAAQTRFLWGTVRVMKPSRFLKEIPRDYLIQVH

Sequences:

>Translated_637_residues
MLTSELNEAQIAAVTSPLSPILVLAGAGAGKTRVVTCRILHLINEGIAPKEILAVTFTNKAAKELKERILHLCPQAHGSD
IPMVCTFHSLGVFILRRSIQALNRENNFIIYDQSDTDKLLKQCLQKFNLKKTLSSSIQYHISQAKNRLLSPEDLDPEEYI
DPVVSIYKEYQQRLHEANALDFDDLLFLTVRLFQEFPEVRKEYSELWKALLIDEYQDTNHAQYKMAQTIAGKHQNIFAVG
DPDQSIYSWRGANIHNILNFEKDYPRALVLRLEDNYRSYGNILNAANALIQNNASRLKKDLRSVKGPGEKIRVFLGKTDK
EEAEFVADEISRLHRRSQIPLSDICIFYRTNFQSRTFEDALLRRRIPYEILGGLSFYKRKEIQDILAFLRMFTAKSDVVA
FDRTVNLPKRGLGPSTISSLIEYALTNNLPILEACNNVLQTQEVKLSKKQQEGLREYLSIFQQLEHAYATLPLNEFVVAT
IRITGYFQVLKEDPDTFEDRKSNLDELASKTFEWEQQNTDGTLENFLDDLALKSSTDDTELIADRVNLMTIHNGKGLEFR
IAFVVGLEENLFPHANSKSSYENLEEERRLCYVGITRAQDLLYLTAAQTRFLWGTVRVMKPSRFLKEIPRDYLIQVH
>Mature_637_residues
MLTSELNEAQIAAVTSPLSPILVLAGAGAGKTRVVTCRILHLINEGIAPKEILAVTFTNKAAKELKERILHLCPQAHGSD
IPMVCTFHSLGVFILRRSIQALNRENNFIIYDQSDTDKLLKQCLQKFNLKKTLSSSIQYHISQAKNRLLSPEDLDPEEYI
DPVVSIYKEYQQRLHEANALDFDDLLFLTVRLFQEFPEVRKEYSELWKALLIDEYQDTNHAQYKMAQTIAGKHQNIFAVG
DPDQSIYSWRGANIHNILNFEKDYPRALVLRLEDNYRSYGNILNAANALIQNNASRLKKDLRSVKGPGEKIRVFLGKTDK
EEAEFVADEISRLHRRSQIPLSDICIFYRTNFQSRTFEDALLRRRIPYEILGGLSFYKRKEIQDILAFLRMFTAKSDVVA
FDRTVNLPKRGLGPSTISSLIEYALTNNLPILEACNNVLQTQEVKLSKKQQEGLREYLSIFQQLEHAYATLPLNEFVVAT
IRITGYFQVLKEDPDTFEDRKSNLDELASKTFEWEQQNTDGTLENFLDDLALKSSTDDTELIADRVNLMTIHNGKGLEFR
IAFVVGLEENLFPHANSKSSYENLEEERRLCYVGITRAQDLLYLTAAQTRFLWGTVRVMKPSRFLKEIPRDYLIQVH

Specific function: Essential helicase [H]

COG id: COG0210

COG function: function code L; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367296, Length=646, Percent_Identity=38.2352941176471, Blast_Score=415, Evalue=1e-117,
Organism=Escherichia coli, GI48994965, Length=645, Percent_Identity=38.6046511627907, Blast_Score=390, Evalue=1e-109,
Organism=Escherichia coli, GI1787196, Length=375, Percent_Identity=28, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6322369, Length=740, Percent_Identity=28.6486486486486, Blast_Score=188, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6324477, Length=655, Percent_Identity=24.7328244274809, Blast_Score=114, Evalue=5e-26,

Paralogues:

None

Copy number: 3000 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005751
- InterPro:   IPR013986
- InterPro:   IPR014017
- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 73186; Mature: 73186

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTSELNEAQIAAVTSPLSPILVLAGAGAGKTRVVTCRILHLINEGIAPKEILAVTFTNK
CCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCEEHHHHHHHHHHCCCCCHHEEEEEECCH
AAKELKERILHLCPQAHGSDIPMVCTFHSLGVFILRRSIQALNRENNFIIYDQSDTDKLL
HHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHH
KQCLQKFNLKKTLSSSIQYHISQAKNRLLSPEDLDPEEYIDPVVSIYKEYQQRLHEANAL
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
DFDDLLFLTVRLFQEFPEVRKEYSELWKALLIDEYQDTNHAQYKMAQTIAGKHQNIFAVG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEC
DPDQSIYSWRGANIHNILNFEKDYPRALVLRLEDNYRSYGNILNAANALIQNNASRLKKD
CCCHHHHHCCCCCHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHH
LRSVKGPGEKIRVFLGKTDKEEAEFVADEISRLHRRSQIPLSDICIFYRTNFQSRTFEDA
HHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCCHHHHH
LLRRRIPYEILGGLSFYKRKEIQDILAFLRMFTAKSDVVAFDRTVNLPKRGLGPSTISSL
HHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHH
IEYALTNNLPILEACNNVLQTQEVKLSKKQQEGLREYLSIFQQLEHAYATLPLNEFVVAT
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEE
IRITGYFQVLKEDPDTFEDRKSNLDELASKTFEWEQQNTDGTLENFLDDLALKSSTDDTE
EEEHHHHHHHHCCCCHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCHHH
LIADRVNLMTIHNGKGLEFRIAFVVGLEENLFPHANSKSSYENLEEERRLCYVGITRAQD
HHHHHHEEEEEECCCCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHCCEEEEEEHHHHH
LLYLTAAQTRFLWGTVRVMKPSRFLKEIPRDYLIQVH
HHEEHHHHHHHHHHHHHHCCHHHHHHHCCHHHEEECC
>Mature Secondary Structure
MLTSELNEAQIAAVTSPLSPILVLAGAGAGKTRVVTCRILHLINEGIAPKEILAVTFTNK
CCCCCCCCHHHHHHHCCCCCEEEEECCCCCCCEEHHHHHHHHHHCCCCCHHEEEEEECCH
AAKELKERILHLCPQAHGSDIPMVCTFHSLGVFILRRSIQALNRENNFIIYDQSDTDKLL
HHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHH
KQCLQKFNLKKTLSSSIQYHISQAKNRLLSPEDLDPEEYIDPVVSIYKEYQQRLHEANAL
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
DFDDLLFLTVRLFQEFPEVRKEYSELWKALLIDEYQDTNHAQYKMAQTIAGKHQNIFAVG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEC
DPDQSIYSWRGANIHNILNFEKDYPRALVLRLEDNYRSYGNILNAANALIQNNASRLKKD
CCCHHHHHCCCCCHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHH
LRSVKGPGEKIRVFLGKTDKEEAEFVADEISRLHRRSQIPLSDICIFYRTNFQSRTFEDA
HHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHEEEEEECCCCCCHHHHH
LLRRRIPYEILGGLSFYKRKEIQDILAFLRMFTAKSDVVAFDRTVNLPKRGLGPSTISSL
HHHHCCCHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHH
IEYALTNNLPILEACNNVLQTQEVKLSKKQQEGLREYLSIFQQLEHAYATLPLNEFVVAT
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEE
IRITGYFQVLKEDPDTFEDRKSNLDELASKTFEWEQQNTDGTLENFLDDLALKSSTDDTE
EEEHHHHHHHHCCCCHHHHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCHHH
LIADRVNLMTIHNGKGLEFRIAFVVGLEENLFPHANSKSSYENLEEERRLCYVGITRAQD
HHHHHHEEEEEECCCCCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHCCEEEEEEHHHHH
LLYLTAAQTRFLWGTVRVMKPSRFLKEIPRDYLIQVH
HHEEHHHHHHHHHHHHHHCCHHHHHHHCCHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA