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The map label for this gene is yggV [C]

Identifier: 62185551

GI number: 62185551

Start: 1112637

End: 1113257

Strand: Direct

Name: yggV [C]

Synonym: CAB952

Alternate gene names: 62185551

Gene position: 1112637-1113257 (Clockwise)

Preceding gene: 62185547

Following gene: 62185554

Centisome position: 97.23

GC content: 38.16

Gene sequence:

>621_bases
ATGAAGATAGTAATTGCTAGCTCCCACGGTTATAAAATACGAGAAACCAAGACTTTTTTAAAACAATTAGGAAGCTTTGA
CATTTTCTCATTAACAGATTTCCCTAACTACTACGCTCCTAAAGAAGTAGGTTCTCTTCCCGAAGAAAACGCTTTAGCAA
AAGGTCTCCACGCAGCACGAGAACTGAACTCTTGGGTAATTGCTGATGACACGATGCTCATGGTCCCTGCATTAAATGGA
CTTCCTGGAAAGCTATCCGCTACTTTTGCCGGAGAAGATGCTTGTGATAAAGACCACAGAAAAAAACTCCTACAAGAAAT
GCAATCTTTAGAAAGCATTGTAGACCGTTCTGCTTACTTTGAATGTTGTATTGTACTTGCTTCACCTGAAGGGAAATTTT
TTAAGACTCGTGGGATTTGTGAAGGCTATATTAGCCATCAAGAAAAAGGTTCTTCTGGTTTTGGTTACGACTCTTTATTT
TTAAAATATGACTACAAACAGACTTTCGCTGAACTTTCCGAAGATATAAAAAATCAAGTCTCTCATAGAGCTAAGGCTTT
ACAAAAGCTCGCCCCTTATTTACAAGACCTGTTAGAGAAACAGCTAGTCTCTAGGAATTAA

Upstream 100 bases:

>100_bases
ATCGCGAAAGGCACTACACTCGACAAAATTACTCATGTAATACCACACGAAACAGAAACTGTTAGTTATTTGCTCTTTCC
CTTTTGCTAAGGAGAAACCC

Downstream 100 bases:

>100_bases
CGTTTCCAATGAATGTTCTAAGCAGCCGCGAATTTCTCGCATCTCTGCAAGTATAGCTTCTGCTCTTAAAAAATCTGCTT
CTAAACTTGCCGTTGCTGGC

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MKIVIASSHGYKIRETKTFLKQLGSFDIFSLTDFPNYYAPKEVGSLPEENALAKGLHAARELNSWVIADDTMLMVPALNG
LPGKLSATFAGEDACDKDHRKKLLQEMQSLESIVDRSAYFECCIVLASPEGKFFKTRGICEGYISHQEKGSSGFGYDSLF
LKYDYKQTFAELSEDIKNQVSHRAKALQKLAPYLQDLLEKQLVSRN

Sequences:

>Translated_206_residues
MKIVIASSHGYKIRETKTFLKQLGSFDIFSLTDFPNYYAPKEVGSLPEENALAKGLHAARELNSWVIADDTMLMVPALNG
LPGKLSATFAGEDACDKDHRKKLLQEMQSLESIVDRSAYFECCIVLASPEGKFFKTRGICEGYISHQEKGSSGFGYDSLF
LKYDYKQTFAELSEDIKNQVSHRAKALQKLAPYLQDLLEKQLVSRN
>Mature_206_residues
MKIVIASSHGYKIRETKTFLKQLGSFDIFSLTDFPNYYAPKEVGSLPEENALAKGLHAARELNSWVIADDTMLMVPALNG
LPGKLSATFAGEDACDKDHRKKLLQEMQSLESIVDRSAYFECCIVLASPEGKFFKTRGICEGYISHQEKGSSGFGYDSLF
LKYDYKQTFAELSEDIKNQVSHRAKALQKLAPYLQDLLEKQLVSRN

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Homo sapiens, GI15626999, Length=204, Percent_Identity=31.3725490196078, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI31657144, Length=153, Percent_Identity=33.9869281045752, Blast_Score=68, Evalue=6e-12,
Organism=Escherichia coli, GI1789324, Length=197, Percent_Identity=35.0253807106599, Blast_Score=104, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17556833, Length=196, Percent_Identity=30.6122448979592, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322529, Length=147, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920712, Length=163, Percent_Identity=34.3558282208589, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_CHLAB (Q5L4Q6)

Other databases:

- EMBL:   CR848038
- RefSeq:   YP_220336.1
- HSSP:   P52061
- ProteinModelPortal:   Q5L4Q6
- SMR:   Q5L4Q6
- GeneID:   3337949
- GenomeReviews:   CR848038_GR
- KEGG:   cab:CAB952
- HOGENOM:   HBG697237
- OMA:   YSKRYDQ
- PhylomeDB:   Q5L4Q6
- ProtClustDB:   PRK00120
- BioCyc:   CABO218497:CAB952-MONOMER
- BRENDA:   3.6.1.15
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 23145; Mature: 23145

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVIASSHGYKIRETKTFLKQLGSFDIFSLTDFPNYYAPKEVGSLPEENALAKGLHAAR
CEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHCCCCCHHHHHHHHHHHH
ELNSWVIADDTMLMVPALNGLPGKLSATFAGEDACDKDHRKKLLQEMQSLESIVDRSAYF
HHCCEEEECCCEEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ECCIVLASPEGKFFKTRGICEGYISHQEKGSSGFGYDSLFLKYDYKQTFAELSEDIKNQV
HEEEEEECCCCCEEHHCCHHHHHHHHHCCCCCCCCCCHHEEEECHHHHHHHHHHHHHHHH
SHRAKALQKLAPYLQDLLEKQLVSRN
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIVIASSHGYKIRETKTFLKQLGSFDIFSLTDFPNYYAPKEVGSLPEENALAKGLHAAR
CEEEEECCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHCCCCCHHHHHHHHHHHH
ELNSWVIADDTMLMVPALNGLPGKLSATFAGEDACDKDHRKKLLQEMQSLESIVDRSAYF
HHCCEEEECCCEEEEECCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ECCIVLASPEGKFFKTRGICEGYISHQEKGSSGFGYDSLFLKYDYKQTFAELSEDIKNQV
HEEEEEECCCCCEEHHCCHHHHHHHHHCCCCCCCCCCHHEEEECHHHHHHHHHHHHHHHH
SHRAKALQKLAPYLQDLLEKQLVSRN
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA