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The map label for this gene is tig

Identifier: 62185489

GI number: 62185489

Start: 1035835

End: 1037160

Strand: Direct

Name: tig

Synonym: CAB887

Alternate gene names: 62185489

Gene position: 1035835-1037160 (Clockwise)

Preceding gene: 62185483

Following gene: 62185490

Centisome position: 90.52

GC content: 38.69

Gene sequence:

>1326_bases
GTGTCGCGAAATTTTTCTAACGAACAATTTTCTGTTAATTTAGAAGAACAGCCTGGGTGTGTTGTTTCTGCTGAAGTAAA
AACTACACCTCAACTGTTAGATAAGCTGCATAAACAGGCTATAAAGAAGATAAAGAAAGATGTCATTTTGCCAGGGTTTC
GCAAAGGCAAAGCTCCTGACGGAATTATCGTTTCTCGCTACCCCAGCCAAGTCACTAAAGAATTAAATCAACTACTCATT
CAATCAGCCTATCAGGCTTTAGCCTCTGTGGGAGACCGAAGACCTCTTTCCCCACAAGCTATCAAATCGACTTCGGTAAC
AAAAGCAGATATCAATGAAGGTGGTCAAGTCAACTTTACCTATGAGGCTTTCCCAACGATTTCTGATATCCCTTGGGATA
AACTCTCCCTATCAGAAGAACCTGCTGTAAAAGATATTACTGATGAAGAAATGGAAAAAGGCTTACAGAATATTTCTTAT
TTCTTCGCAACTAAAACTCCTGTAACTCGTACTTCTCAAGAAGGCGACTTCATCTCACTATCTCTTCATGTATCCAAACA
AAATGAAGAAGGCGTCCCTACACCAATTTTTGAAAATAAATACTTCAAACTTTGTGAAGAGGAAATGACCGACGCTTTCA
AAACTAAGTTTCTAGGCATTTCTGCAGGTCACCGTGTGACTGAAATTATCGCATCCCCCGAAATCCAATCATTCCTCAAC
GGAGATGTTTTAACTTTTACTGTTAACGCGGTTATTGAAGTTGTTGCTCCTGAGCTTGATGATGATAAAGCTCGTCAGCT
ACAAGCTGAATCCCTAGAAGATTTAAAGAAAAAGCTACGCATTCAATTAGAAAATCAAGCAAAAGATAGACAACACCAAC
AGTGCTTTGCTGAGGCAGAAAATGCCTTGGCAAGTATTATCGATTTCGACCTTCCCACATCGATGTTAGAAGATCGTTTA
GCTATGCTAACCAGAGCAAAACTACTCAACGCTCGATTGATTCAATATTGTTCTGATGAAGAACTAGAAAATAAAAAATC
AGATTTATTAAAAGAAGCGGAATTAGAAGCTAAAAAAACTTTAAAACTGTTTTTCCTAGCGAATAAGATTTTCAATGATG
AAAAGCTTGTGATCAGTCGTGAAGAGCTTCAATATATGATGGATGTATGTTCTAGGGAACGTTATGGCATGCAGCCTCCT
CGAGATATCTCTAAAGAAGCTTTACAAGAATTAGTGATGGCAGCTCGTGATCGCTTAACTTACCATAAAGCTATGGAAAA
AGTTCTAGCCAAAGCAAAAGAATCAGCGACAGCGCCCTCTGCATAA

Upstream 100 bases:

>100_bases
TGTAGCTCAGTGGTAGAGCGCCACGTTGCCAACGTGAAGGTCGTGAGTTCAAGCCTCATCACCCGCTTTTCCTTCCAGAA
AAGCTTCAAAGGGTAGTCTT

Downstream 100 bases:

>100_bases
TTGAGCTAGAGGAAAACACTTGACCCAAGAAAGTCTTAAACATAGAATTCAACATTTTAATGTGTAGGCTTGTTTTCAAG
TAAAACAGCATAAAAAAATA

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MSRNFSNEQFSVNLEEQPGCVVSAEVKTTPQLLDKLHKQAIKKIKKDVILPGFRKGKAPDGIIVSRYPSQVTKELNQLLI
QSAYQALASVGDRRPLSPQAIKSTSVTKADINEGGQVNFTYEAFPTISDIPWDKLSLSEEPAVKDITDEEMEKGLQNISY
FFATKTPVTRTSQEGDFISLSLHVSKQNEEGVPTPIFENKYFKLCEEEMTDAFKTKFLGISAGHRVTEIIASPEIQSFLN
GDVLTFTVNAVIEVVAPELDDDKARQLQAESLEDLKKKLRIQLENQAKDRQHQQCFAEAENALASIIDFDLPTSMLEDRL
AMLTRAKLLNARLIQYCSDEELENKKSDLLKEAELEAKKTLKLFFLANKIFNDEKLVISREELQYMMDVCSRERYGMQPP
RDISKEALQELVMAARDRLTYHKAMEKVLAKAKESATAPSA

Sequences:

>Translated_441_residues
MSRNFSNEQFSVNLEEQPGCVVSAEVKTTPQLLDKLHKQAIKKIKKDVILPGFRKGKAPDGIIVSRYPSQVTKELNQLLI
QSAYQALASVGDRRPLSPQAIKSTSVTKADINEGGQVNFTYEAFPTISDIPWDKLSLSEEPAVKDITDEEMEKGLQNISY
FFATKTPVTRTSQEGDFISLSLHVSKQNEEGVPTPIFENKYFKLCEEEMTDAFKTKFLGISAGHRVTEIIASPEIQSFLN
GDVLTFTVNAVIEVVAPELDDDKARQLQAESLEDLKKKLRIQLENQAKDRQHQQCFAEAENALASIIDFDLPTSMLEDRL
AMLTRAKLLNARLIQYCSDEELENKKSDLLKEAELEAKKTLKLFFLANKIFNDEKLVISREELQYMMDVCSRERYGMQPP
RDISKEALQELVMAARDRLTYHKAMEKVLAKAKESATAPSA
>Mature_440_residues
SRNFSNEQFSVNLEEQPGCVVSAEVKTTPQLLDKLHKQAIKKIKKDVILPGFRKGKAPDGIIVSRYPSQVTKELNQLLIQ
SAYQALASVGDRRPLSPQAIKSTSVTKADINEGGQVNFTYEAFPTISDIPWDKLSLSEEPAVKDITDEEMEKGLQNISYF
FATKTPVTRTSQEGDFISLSLHVSKQNEEGVPTPIFENKYFKLCEEEMTDAFKTKFLGISAGHRVTEIIASPEIQSFLNG
DVLTFTVNAVIEVVAPELDDDKARQLQAESLEDLKKKLRIQLENQAKDRQHQQCFAEAENALASIIDFDLPTSMLEDRLA
MLTRAKLLNARLIQYCSDEELENKKSDLLKEAELEAKKTLKLFFLANKIFNDEKLVISREELQYMMDVCSRERYGMQPPR
DISKEALQELVMAARDRLTYHKAMEKVLAKAKESATAPSA

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain

Homologues:

None

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): TIG_CHLAB (Q5L4W8)

Other databases:

- EMBL:   CR848038
- RefSeq:   YP_220274.1
- ProteinModelPortal:   Q5L4W8
- SMR:   Q5L4W8
- GeneID:   3338218
- GenomeReviews:   CR848038_GR
- KEGG:   cab:CAB887
- HOGENOM:   HBG402733
- OMA:   NARLIQY
- ProtClustDB:   PRK01490
- BioCyc:   CABO218497:CAB887-MONOMER
- HAMAP:   MF_00303
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881
- Gene3D:   G3DSA:1.10.3120.10
- Gene3D:   G3DSA:3.30.70.1050
- PIRSF:   PIRSF003095
- TIGRFAMs:   TIGR00115

Pfam domain/function: PF05698 Trigger_C; PF05697 Trigger_N; SSF109998 Trigger_fac_C_bac; SSF102735 Trigger_fac_ribosome-bd_bac

EC number: NA

Molecular weight: Translated: 49748; Mature: 49617

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRNFSNEQFSVNLEEQPGCVVSAEVKTTPQLLDKLHKQAIKKIKKDVILPGFRKGKAPD
CCCCCCCCEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GIIVSRYPSQVTKELNQLLIQSAYQALASVGDRRPLSPQAIKSTSVTKADINEGGQVNFT
CEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHCCCCCEEEEE
YEAFPTISDIPWDKLSLSEEPAVKDITDEEMEKGLQNISYFFATKTPVTRTSQEGDFISL
EECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCCCEEEE
SLHVSKQNEEGVPTPIFENKYFKLCEEEMTDAFKTKFLGISAGHRVTEIIASPEIQSFLN
EEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHC
GDVLTFTVNAVIEVVAPELDDDKARQLQAESLEDLKKKLRIQLENQAKDRQHQQCFAEAE
CCEEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NALASIIDFDLPTSMLEDRLAMLTRAKLLNARLIQYCSDEELENKKSDLLKEAELEAKKT
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LKLFFLANKIFNDEKLVISREELQYMMDVCSRERYGMQPPRDISKEALQELVMAARDRLT
HHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
YHKAMEKVLAKAKESATAPSA
HHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SRNFSNEQFSVNLEEQPGCVVSAEVKTTPQLLDKLHKQAIKKIKKDVILPGFRKGKAPD
CCCCCCCEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GIIVSRYPSQVTKELNQLLIQSAYQALASVGDRRPLSPQAIKSTSVTKADINEGGQVNFT
CEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCHHCCCCCEEEEE
YEAFPTISDIPWDKLSLSEEPAVKDITDEEMEKGLQNISYFFATKTPVTRTSQEGDFISL
EECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCCCEEEE
SLHVSKQNEEGVPTPIFENKYFKLCEEEMTDAFKTKFLGISAGHRVTEIIASPEIQSFLN
EEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCHHHHHHHC
GDVLTFTVNAVIEVVAPELDDDKARQLQAESLEDLKKKLRIQLENQAKDRQHQQCFAEAE
CCEEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NALASIIDFDLPTSMLEDRLAMLTRAKLLNARLIQYCSDEELENKKSDLLKEAELEAKKT
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LKLFFLANKIFNDEKLVISREELQYMMDVCSRERYGMQPPRDISKEALQELVMAARDRLT
HHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
YHKAMEKVLAKAKESATAPSA
HHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA