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The map label for this gene is map [H]

Identifier: 62185333

GI number: 62185333

Start: 834046

End: 834918

Strand: Direct

Name: map [H]

Synonym: CAB720

Alternate gene names: 62185333

Gene position: 834046-834918 (Clockwise)

Preceding gene: 62185332

Following gene: 62185336

Centisome position: 72.88

GC content: 40.44

Gene sequence:

>873_bases
ATGAAAAGAAATGATCCCTGCTGGTGTGGAAGCAAACGTAAATGGAAATATTGCCATCCTCTGGCCCCTAAACTATCTTG
GGAACAACAAAAACAATATTACGCTTCGCAATACGATATTATTTTAAAGACTCCAAAACAAATCGAAAAAATCCGTCATG
CTTGTCAAATAACTGCGCATATACTCGACGCTCTTTGCCAAGCATCTAAAGAAGGCGTAACTACAGAGGACTTAGACCAA
CTCTCCCGTCAATTACATAAAGAATATGACGCAATTCCAGCACCTCTAAATTATGGCTCTCCTCCTTTCCCAAAAACGAT
TTGCACTTCACTGAATGAAGTGATCTGTCACGGCATTCCTAACAATACCCCTTTAAAAAACGGCGATATCATGAACATCG
ATGTTTCTTGTATTGTTGATGGGTATTACGGAGATTGTAGCAATATGGTCATGATTGGCGAGGTCTCTGAAATAAAAAAA
CGCGTCTGTCAAGCATCTTTAGATTGTTTGAACGCAGCAATTGCTAGATTAAAGCCCTATGTACCTCTATACGAAATCGG
CGAAGCTATAGAAGCTTGTGCCGATAGTTATGGATTTTCTGTAGTAGATCAGTTTGTAGGTCACGGTGTGGGTATAAAAT
TCCATGAAAACCCCTATGTCCCGCATTACAGGAATCGTAGTGCTATACCCTTGGCTCCTGGTATGATATTTACTATAGAG
CCCATGATCAACGTAGGCAAAAAAGAAGGGGTTATAGATCCCAATAACCATTGGGAAGCAAGAACTTGCGACAATCAACC
TAGCGCACAGTGGGAACACACCCTACTTATTACTGAGACAGGTTATGAGATACTAACTCTTCTAGAGAAATAA

Upstream 100 bases:

>100_bases
ATTATTCAGCATCGCGTTATTATTAATGTCGGCAAACCTCATGCTTAAAGGTATTTCAATAGCATTTAATATAGGATTTT
ATATTCAGTAGTGTAGATAA

Downstream 100 bases:

>100_bases
TTTCTTCTTCCAGAGATTCTATATGCTCTAGAAGATTCTGAATTATCTCAATGTCTCTCATGTCTGTAAAGGTAGAGACA
TTTTCTTCTTGTTTTTGGAG

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MKRNDPCWCGSKRKWKYCHPLAPKLSWEQQKQYYASQYDIILKTPKQIEKIRHACQITAHILDALCQASKEGVTTEDLDQ
LSRQLHKEYDAIPAPLNYGSPPFPKTICTSLNEVICHGIPNNTPLKNGDIMNIDVSCIVDGYYGDCSNMVMIGEVSEIKK
RVCQASLDCLNAAIARLKPYVPLYEIGEAIEACADSYGFSVVDQFVGHGVGIKFHENPYVPHYRNRSAIPLAPGMIFTIE
PMINVGKKEGVIDPNNHWEARTCDNQPSAQWEHTLLITETGYEILTLLEK

Sequences:

>Translated_290_residues
MKRNDPCWCGSKRKWKYCHPLAPKLSWEQQKQYYASQYDIILKTPKQIEKIRHACQITAHILDALCQASKEGVTTEDLDQ
LSRQLHKEYDAIPAPLNYGSPPFPKTICTSLNEVICHGIPNNTPLKNGDIMNIDVSCIVDGYYGDCSNMVMIGEVSEIKK
RVCQASLDCLNAAIARLKPYVPLYEIGEAIEACADSYGFSVVDQFVGHGVGIKFHENPYVPHYRNRSAIPLAPGMIFTIE
PMINVGKKEGVIDPNNHWEARTCDNQPSAQWEHTLLITETGYEILTLLEK
>Mature_290_residues
MKRNDPCWCGSKRKWKYCHPLAPKLSWEQQKQYYASQYDIILKTPKQIEKIRHACQITAHILDALCQASKEGVTTEDLDQ
LSRQLHKEYDAIPAPLNYGSPPFPKTICTSLNEVICHGIPNNTPLKNGDIMNIDVSCIVDGYYGDCSNMVMIGEVSEIKK
RVCQASLDCLNAAIARLKPYVPLYEIGEAIEACADSYGFSVVDQFVGHGVGIKFHENPYVPHYRNRSAIPLAPGMIFTIE
PMINVGKKEGVIDPNNHWEARTCDNQPSAQWEHTLLITETGYEILTLLEK

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI40385867, Length=249, Percent_Identity=41.7670682730924, Blast_Score=202, Evalue=2e-52,
Organism=Homo sapiens, GI164420681, Length=269, Percent_Identity=42.0074349442379, Blast_Score=199, Evalue=2e-51,
Organism=Escherichia coli, GI1786364, Length=251, Percent_Identity=44.2231075697211, Blast_Score=211, Evalue=5e-56,
Organism=Escherichia coli, GI1788728, Length=256, Percent_Identity=24.609375, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71996291, Length=270, Percent_Identity=41.1111111111111, Blast_Score=192, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6323273, Length=246, Percent_Identity=44.7154471544715, Blast_Score=200, Evalue=2e-52,
Organism=Drosophila melanogaster, GI21355531, Length=269, Percent_Identity=41.635687732342, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24583427, Length=245, Percent_Identity=40, Blast_Score=192, Evalue=2e-49,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467
- InterPro:   IPR004027 [H]

Pfam domain/function: PF00557 Peptidase_M24; PF02810 SEC-C [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 32684; Mature: 32684

Theoretical pI: Translated: 6.49; Mature: 6.49

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRNDPCWCGSKRKWKYCHPLAPKLSWEQQKQYYASQYDIILKTPKQIEKIRHACQITAH
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCEEEEECHHHHHHHHHHHHHHHH
ILDALCQASKEGVTTEDLDQLSRQLHKEYDAIPAPLNYGSPPFPKTICTSLNEVICHGIP
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
NNTPLKNGDIMNIDVSCIVDGYYGDCSNMVMIGEVSEIKKRVCQASLDCLNAAIARLKPY
CCCCCCCCCEEEEEEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCC
VPLYEIGEAIEACADSYGFSVVDQFVGHGVGIKFHENPYVPHYRNRSAIPLAPGMIFTIE
CCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEEC
PMINVGKKEGVIDPNNHWEARTCDNQPSAQWEHTLLITETGYEILTLLEK
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHCC
>Mature Secondary Structure
MKRNDPCWCGSKRKWKYCHPLAPKLSWEQQKQYYASQYDIILKTPKQIEKIRHACQITAH
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCEEEEECHHHHHHHHHHHHHHHH
ILDALCQASKEGVTTEDLDQLSRQLHKEYDAIPAPLNYGSPPFPKTICTSLNEVICHGIP
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
NNTPLKNGDIMNIDVSCIVDGYYGDCSNMVMIGEVSEIKKRVCQASLDCLNAAIARLKPY
CCCCCCCCCEEEEEEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCC
VPLYEIGEAIEACADSYGFSVVDQFVGHGVGIKFHENPYVPHYRNRSAIPLAPGMIFTIE
CCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEEC
PMINVGKKEGVIDPNNHWEARTCDNQPSAQWEHTLLITETGYEILTLLEK
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]