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The map label for this gene is aroC

Identifier: 62185305

GI number: 62185305

Start: 802200

End: 803279

Strand: Direct

Name: aroC

Synonym: CAB692

Alternate gene names: 62185305

Gene position: 802200-803279 (Clockwise)

Preceding gene: 62185304

Following gene: 62185306

Centisome position: 70.1

GC content: 43.43

Gene sequence:

>1080_bases
ATGAGAAATCGCTTTGGTTCTTTATTTTCTCTAACGACATGGGGAGAATCTCATGGACCTTGTCTTGGGGTTGTTATCGA
CGGGTGCCCTGCAGGGCTACAACTCTCCCCTGAAGATTTTGTTCCTGCTATGTCGCGCAGATGCCCAGGACGACCTGGAA
CATCTCCACGTAAAGAAGCGGACACTGTGCATATTCTTTCCGGAATCTATCAAGGCAAAACAACAGGAACACCCATTGCT
CTGCAAATTTTTAATACTGATGTAAACAGCGATCCATATCGCGAACAAGACGATCGCTACCGTCCAGGACATGGACAATT
TGCTTATGAGAAAAAATATGGCATTGTAGACCCCCTAGGAGGAGGCAGGTCATCCGGAAGAGAAACTGCATGCCGCGTAG
CTGCCGGGGTCATCGCAGCAAAATTTCTCGCGCATTATGATATTCATTGTTTAGCTTTCTTATCTAAATTAGGACAGGTA
TCTATTGAGGAATATCCAAAATATTCTAAAGAATTTGCGCAAAGCATTTACAATTCGCCTTTTCTTTCTCCGCTAAACCA
TGACGCTATCTTTCAAATCATCACCGACCTACAAAATACACAAGACTCGTTAGGAGGTGTGGTATCTTTTATTACTTCTC
CTATTCATGAAAGCCTGGGCGAACCCGTATTCAGTAAAGTACAAGCCATGTTGGCTTCTGCGTTGATGAGCATTCCGGCA
GCTAAAGGATTTGAAATAGGGTTAGGATTCGCTTCTGCGGATAGGTATGGATCGGAATATATTGATCCTATTATCATCGA
AGACGGAAGAATTTCCATGAGATCGAATAATTGCGGCGGATCTTTAGGAGGGATTACTATAGGAATGCCCTTAAATGGTC
GGGTAGTGTTTAAACCGACATCTTCTATTCACAAACCCTGTGGCACAGTAACGAAAACTGGGGAACCTACAAGCTATGTT
ACGCAAAAAGGTAGTCGTCATGATCCCTGTGTTACTATAAGAGCTGTAGGTGTCGTAGAAGCCATGGTAAATCTTGTCCT
AGCTGATTTGTTATTACAACAACGATGTGCGAGACTATGA

Upstream 100 bases:

>100_bases
AACGCATCTGTGACTATCACTTCCCTCTTGATGAGGTAAATCTTTTAGATGAACGTTCATTATTCTCTGCGTGTGAATCT
TTTACTACTTTACTAAATCA

Downstream 100 bases:

>100_bases
TCGAAAACTTGATTTCTCATCCTCATCATATCAAACTTGTGGGAGACTTCTTCAATAAAAAGTTATTTTCTTCCATATCT
ACAGATCATCCGCTTGTCAT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MRNRFGSLFSLTTWGESHGPCLGVVIDGCPAGLQLSPEDFVPAMSRRCPGRPGTSPRKEADTVHILSGIYQGKTTGTPIA
LQIFNTDVNSDPYREQDDRYRPGHGQFAYEKKYGIVDPLGGGRSSGRETACRVAAGVIAAKFLAHYDIHCLAFLSKLGQV
SIEEYPKYSKEFAQSIYNSPFLSPLNHDAIFQIITDLQNTQDSLGGVVSFITSPIHESLGEPVFSKVQAMLASALMSIPA
AKGFEIGLGFASADRYGSEYIDPIIIEDGRISMRSNNCGGSLGGITIGMPLNGRVVFKPTSSIHKPCGTVTKTGEPTSYV
TQKGSRHDPCVTIRAVGVVEAMVNLVLADLLLQQRCARL

Sequences:

>Translated_359_residues
MRNRFGSLFSLTTWGESHGPCLGVVIDGCPAGLQLSPEDFVPAMSRRCPGRPGTSPRKEADTVHILSGIYQGKTTGTPIA
LQIFNTDVNSDPYREQDDRYRPGHGQFAYEKKYGIVDPLGGGRSSGRETACRVAAGVIAAKFLAHYDIHCLAFLSKLGQV
SIEEYPKYSKEFAQSIYNSPFLSPLNHDAIFQIITDLQNTQDSLGGVVSFITSPIHESLGEPVFSKVQAMLASALMSIPA
AKGFEIGLGFASADRYGSEYIDPIIIEDGRISMRSNNCGGSLGGITIGMPLNGRVVFKPTSSIHKPCGTVTKTGEPTSYV
TQKGSRHDPCVTIRAVGVVEAMVNLVLADLLLQQRCARL
>Mature_359_residues
MRNRFGSLFSLTTWGESHGPCLGVVIDGCPAGLQLSPEDFVPAMSRRCPGRPGTSPRKEADTVHILSGIYQGKTTGTPIA
LQIFNTDVNSDPYREQDDRYRPGHGQFAYEKKYGIVDPLGGGRSSGRETACRVAAGVIAAKFLAHYDIHCLAFLSKLGQV
SIEEYPKYSKEFAQSIYNSPFLSPLNHDAIFQIITDLQNTQDSLGGVVSFITSPIHESLGEPVFSKVQAMLASALMSIPA
AKGFEIGLGFASADRYGSEYIDPIIIEDGRISMRSNNCGGSLGGITIGMPLNGRVVFKPTSSIHKPCGTVTKTGEPTSYV
TQKGSRHDPCVTIRAVGVVEAMVNLVLADLLLQQRCARL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=358, Percent_Identity=44.6927374301676, Blast_Score=253, Evalue=2e-68,
Organism=Saccharomyces cerevisiae, GI6321290, Length=368, Percent_Identity=42.1195652173913, Blast_Score=253, Evalue=3e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_CHLAB (Q5L5F2)

Other databases:

- EMBL:   CR848038
- RefSeq:   YP_220090.1
- HSSP:   P28777
- ProteinModelPortal:   Q5L5F2
- SMR:   Q5L5F2
- GeneID:   3337261
- GenomeReviews:   CR848038_GR
- KEGG:   cab:CAB692
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- PhylomeDB:   Q5L5F2
- ProtClustDB:   PRK05382
- BioCyc:   CABO218497:CAB692-MONOMER
- BRENDA:   4.2.3.5
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 38705; Mature: 38705

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNRFGSLFSLTTWGESHGPCLGVVIDGCPAGLQLSPEDFVPAMSRRCPGRPGTSPRKEA
CCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCEECHHHHHHHHHHCCCCCCCCCCCHHH
DTVHILSGIYQGKTTGTPIALQIFNTDVNSDPYREQDDRYRPGHGQFAYEKKYGIVDPLG
HHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCC
GGRSSGRETACRVAAGVIAAKFLAHYDIHCLAFLSKLGQVSIEEYPKYSKEFAQSIYNSP
CCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHCCC
FLSPLNHDAIFQIITDLQNTQDSLGGVVSFITSPIHESLGEPVFSKVQAMLASALMSIPA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
AKGFEIGLGFASADRYGSEYIDPIIIEDGRISMRSNNCGGSLGGITIGMPLNGRVVFKPT
CCCCEEECCCHHHHHCCHHCCCCEEEECCEEEEECCCCCCCCCCEEEECCCCCEEEECCC
SSIHKPCGTVTKTGEPTSYVTQKGSRHDPCVTIRAVGVVEAMVNLVLADLLLQQRCARL
HHHHCCCCCCCCCCCCHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRNRFGSLFSLTTWGESHGPCLGVVIDGCPAGLQLSPEDFVPAMSRRCPGRPGTSPRKEA
CCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCEECHHHHHHHHHHCCCCCCCCCCCHHH
DTVHILSGIYQGKTTGTPIALQIFNTDVNSDPYREQDDRYRPGHGQFAYEKKYGIVDPLG
HHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCC
GGRSSGRETACRVAAGVIAAKFLAHYDIHCLAFLSKLGQVSIEEYPKYSKEFAQSIYNSP
CCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHCCC
FLSPLNHDAIFQIITDLQNTQDSLGGVVSFITSPIHESLGEPVFSKVQAMLASALMSIPA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
AKGFEIGLGFASADRYGSEYIDPIIIEDGRISMRSNNCGGSLGGITIGMPLNGRVVFKPT
CCCCEEECCCHHHHHCCHHCCCCEEEECCEEEEECCCCCCCCCCEEEECCCCCEEEECCC
SSIHKPCGTVTKTGEPTSYVTQKGSRHDPCVTIRAVGVVEAMVNLVLADLLLQQRCARL
HHHHCCCCCCCCCCCCHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA