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The map label for this gene is moaE [H]

Identifier: 62185297

GI number: 62185297

Start: 794643

End: 795434

Strand: Direct

Name: moaE [H]

Synonym: CAB684

Alternate gene names: 62185297

Gene position: 794643-795434 (Clockwise)

Preceding gene: 62185296

Following gene: 62185298

Centisome position: 69.44

GC content: 42.42

Gene sequence:

>792_bases
GTGTTTGCCTCAACTTTTGTGTTAGCAACAACACAGGAAAACCCTCCGTGTGTCATACTGACAGGAGCTTCGGGGCAACT
AGGTTCAGCAATCGCCTTGTATCTTCACGAACGAGATTATTATCTCCTACTTGTAGGAAGACAACACGATAAGCTTCGGA
GACTACACGAACACAACCCTAATTCTTCGACCCTAGCTATAGACTATTCTTTCCCCGGATATCTTGCAGATTATAAAAAA
ACTCTTAAAGAGCTCAATCGCCCTATTCAAGGGCTGATCATTTCCACACCTCGCCCTATTTGGGGAAGCATTTTACAATC
CCCGGAATCTTGGGAATCTACATTACAAATAGCTTTTATCGCACAGACGGCTCTAATTCAAGCCACACTCCCCTATATGA
GTTCTCCAAGTTCTATTGTGATCATAGGAGGAACGACATCTGTACAACACCTACCCGCTTACAGCCTATCCTGTGTGATT
CGTCGTATGTGGACAACGTATGCTAAAGCTCTGGCTTATGAATTAGGCCCTAAAGGCATTCGTGTAAACGTTGTCTCTCC
AGGAGCTGTACTCACTCCTTTTCATAAAGGTAGAATCCAAGAAAAAGCTAGGGTAAATCAATCTAGCTATACGGAAGAAT
ATAATAAGGAGACTGAAGAAATACCTTTACGTCGTCATTGCGAATCTGAAGAGCTAGCAAAAACTATAGAGTTTCTCCTA
ACACCATCCTCATCGTTTATTTCAGGGGTCAATTTACTTTTGGATGGAGGGTTTACCTCTTCTCTGAACTAA

Upstream 100 bases:

>100_bases
AACGCCCAATAACCCAAGCTTCTGACTGCACTCTTAACGTTCTAGGAATTACATGCGACCAAGTAGAAAACTCATCCAAT
ATGCTATAACCATCCTCACT

Downstream 100 bases:

>100_bases
CTCCAGTTTTCCCACTGTCAACTGCTGCACTCTATCTAAATCAAATAAAGTGATAGGGAAGGATCCCACCCGCAGCACGA
CACTTTCTGTTGAACACAGG

Product: putative monoamine dehydrogenase/reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MFASTFVLATTQENPPCVILTGASGQLGSAIALYLHERDYYLLLVGRQHDKLRRLHEHNPNSSTLAIDYSFPGYLADYKK
TLKELNRPIQGLIISTPRPIWGSILQSPESWESTLQIAFIAQTALIQATLPYMSSPSSIVIIGGTTSVQHLPAYSLSCVI
RRMWTTYAKALAYELGPKGIRVNVVSPGAVLTPFHKGRIQEKARVNQSSYTEEYNKETEEIPLRRHCESEELAKTIEFLL
TPSSSFISGVNLLLDGGFTSSLN

Sequences:

>Translated_263_residues
MFASTFVLATTQENPPCVILTGASGQLGSAIALYLHERDYYLLLVGRQHDKLRRLHEHNPNSSTLAIDYSFPGYLADYKK
TLKELNRPIQGLIISTPRPIWGSILQSPESWESTLQIAFIAQTALIQATLPYMSSPSSIVIIGGTTSVQHLPAYSLSCVI
RRMWTTYAKALAYELGPKGIRVNVVSPGAVLTPFHKGRIQEKARVNQSSYTEEYNKETEEIPLRRHCESEELAKTIEFLL
TPSSSFISGVNLLLDGGFTSSLN
>Mature_263_residues
MFASTFVLATTQENPPCVILTGASGQLGSAIALYLHERDYYLLLVGRQHDKLRRLHEHNPNSSTLAIDYSFPGYLADYKK
TLKELNRPIQGLIISTPRPIWGSILQSPESWESTLQIAFIAQTALIQATLPYMSSPSSIVIIGGTTSVQHLPAYSLSCVI
RRMWTTYAKALAYELGPKGIRVNVVSPGAVLTPFHKGRIQEKARVNQSSYTEEYNKETEEIPLRRHCESEELAKTIEFLL
TPSSSFISGVNLLLDGGFTSSLN

Specific function: Might catalyze the conversion of monoamine compounds or their metabolites [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=167, Percent_Identity=31.7365269461078, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=24.4979919678715, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI126723750, Length=165, Percent_Identity=29.6969696969697, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=26.6129032258064, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=26.6666666666667, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=27.1653543307087, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=259, Percent_Identity=26.2548262548263, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21355319, Length=258, Percent_Identity=27.5193798449612, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=25.9109311740891, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644337, Length=118, Percent_Identity=34.7457627118644, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 29175; Mature: 29175

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFASTFVLATTQENPPCVILTGASGQLGSAIALYLHERDYYLLLVGRQHDKLRRLHEHNP
CCCCEEEEEEECCCCCEEEEECCCCCCCCEEEEEEECCCEEEEEEECCHHHHHHHHHCCC
NSSTLAIDYSFPGYLADYKKTLKELNRPIQGLIISTPRPIWGSILQSPESWESTLQIAFI
CCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCCCCCHHHHEEEEEH
AQTALIQATLPYMSSPSSIVIIGGTTSVQHLPAYSLSCVIRRMWTTYAKALAYELGPKGI
HHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCE
RVNVVSPGAVLTPFHKGRIQEKARVNQSSYTEEYNKETEEIPLRRHCESEELAKTIEFLL
EEEEECCCCEECCCHHCCHHHHHHCCHHHHHHHHCCHHHCCCHHHCCCHHHHHHHHHHHC
TPSSSFISGVNLLLDGGFTSSLN
CCCHHHHCCEEEEEECCCCCCCC
>Mature Secondary Structure
MFASTFVLATTQENPPCVILTGASGQLGSAIALYLHERDYYLLLVGRQHDKLRRLHEHNP
CCCCEEEEEEECCCCCEEEEECCCCCCCCEEEEEEECCCEEEEEEECCHHHHHHHHHCCC
NSSTLAIDYSFPGYLADYKKTLKELNRPIQGLIISTPRPIWGSILQSPESWESTLQIAFI
CCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCCCCCHHHHEEEEEH
AQTALIQATLPYMSSPSSIVIIGGTTSVQHLPAYSLSCVIRRMWTTYAKALAYELGPKGI
HHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCE
RVNVVSPGAVLTPFHKGRIQEKARVNQSSYTEEYNKETEEIPLRRHCESEELAKTIEFLL
EEEEECCCCEECCCHHCCHHHHHHCCHHHHHHHHCCHHHCCCHHHCCCHHHHHHHHHHHC
TPSSSFISGVNLLLDGGFTSSLN
CCCHHHHCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7590328 [H]