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The map label for this gene is groES [H]

Identifier: 62185226

GI number: 62185226

Start: 705281

End: 705589

Strand: Direct

Name: groES [H]

Synonym: CAB614

Alternate gene names: 62185226

Gene position: 705281-705589 (Clockwise)

Preceding gene: 62185225

Following gene: 62185227

Centisome position: 61.63

GC content: 42.72

Gene sequence:

>309_bases
ATGTCAGATCAAGCAACGACCCTTAGGATTAAGCCCCTGGGTGATAGAATTTTAGTGAAAAGAGAAGAAGAAGATTCTAC
ACCGCGCGGCGGCATCATTTTACCTGATACAGCAAAGAAAAAACAAGACCGAGCAGAAGTGCTAGCCCTAGGAACAGGGA
AGCGTGATAAAGACGGTCAAGTCCTACCTTTTGAAGTTAAAGTAGGTGATACTGTTTTAATAGATAAATACGCGGGACAA
GAACTTACCATCGATGGTGAGGAGTACGTCATTGTTCAAGAAAGCGAAGTTATGGCAGTTCTCAAGTAA

Upstream 100 bases:

>100_bases
TTATTAAGTGCTAAAATCATTGCCAAAAACATGGGGCTCTGCTATCGTTTTCGAGAAACGGCAAAGTCTCTTAGAATATG
AAACACAAGGAGCTTACAAT

Downstream 100 bases:

>100_bases
GACTGATAATTATTTATAGATTGCAAAAAGTTAAGGAGCACAAAAAACAATGGCAGCAAAAAATATTAAATATAACGAAG
ACGCCAGAAAAAAAATCCAC

Product: co-chaperonin GroES

Products: NA

Alternate protein names: 11.2 kDa stress response protein; GroES protein; Protein Cpn10 [H]

Number of amino acids: Translated: 102; Mature: 101

Protein sequence:

>102_residues
MSDQATTLRIKPLGDRILVKREEEDSTPRGGIILPDTAKKKQDRAEVLALGTGKRDKDGQVLPFEVKVGDTVLIDKYAGQ
ELTIDGEEYVIVQESEVMAVLK

Sequences:

>Translated_102_residues
MSDQATTLRIKPLGDRILVKREEEDSTPRGGIILPDTAKKKQDRAEVLALGTGKRDKDGQVLPFEVKVGDTVLIDKYAGQ
ELTIDGEEYVIVQESEVMAVLK
>Mature_101_residues
SDQATTLRIKPLGDRILVKREEEDSTPRGGIILPDTAKKKQDRAEVLALGTGKRDKDGQVLPFEVKVGDTVLIDKYAGQE
LTIDGEEYVIVQESEVMAVLK

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [H]

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family [H]

Homologues:

Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=42.7083333333333, Blast_Score=81, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17555568, Length=93, Percent_Identity=36.5591397849462, Blast_Score=71, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6324594, Length=91, Percent_Identity=35.1648351648352, Blast_Score=60, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21356029, Length=100, Percent_Identity=37, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21358317, Length=95, Percent_Identity=40, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032 [H]

Pfam domain/function: PF00166 Cpn10 [H]

EC number: NA

Molecular weight: Translated: 11268; Mature: 11137

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQATTLRIKPLGDRILVKREEEDSTPRGGIILPDTAKKKQDRAEVLALGTGKRDKDGQ
CCCCCEEEEEEECCCEEEEEECCCCCCCCCCEEECCCCCCCCCCEEEEEEECCCCCCCCC
VLPFEVKVGDTVLIDKYAGQELTIDGEEYVIVQESEVMAVLK
EEEEEEEECCEEEEEECCCCEEEECCCEEEEEECCCEEEEEC
>Mature Secondary Structure 
SDQATTLRIKPLGDRILVKREEEDSTPRGGIILPDTAKKKQDRAEVLALGTGKRDKDGQ
CCCCEEEEEEECCCEEEEEECCCCCCCCCCEEECCCCCCCCCCEEEEEEECCCCCCCCC
VLPFEVKVGDTVLIDKYAGQELTIDGEEYVIVQESEVMAVLK
EEEEEEEECCEEEEEECCCCEEEECCCEEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2571668; 12682364 [H]