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The map label for this gene is coaD

Identifier: 23501973

GI number: 23501973

Start: 1069145

End: 1069639

Strand: Reverse

Name: coaD

Synonym: BR1095

Alternate gene names: 23501973

Gene position: 1069639-1069145 (Counterclockwise)

Preceding gene: 23501974

Following gene: 23501972

Centisome position: 50.75

GC content: 55.76

Gene sequence:

>495_bases
ATGACGATCGCGATCTATGCGGGTTCCTTTGACCCGGTAACCAACGGCCATATAGATGTCCTTAAAGGGGCCTTGCGCCT
TGCCGATCAGGTTATTGTTGCCATCGGCATGCATCCTGGCAAAAAACCGCTTTTCAGTTTTGATGAGCGCGTTGCGCTTA
TTGAGGCAAGTGCGAAGGCGGTTCTGCACAAGGATGCTGCGCGTGTTTCCGTCATCGCTTTTGATGGGCTGGTCATTGAT
GCTGCGCGCAAGCATGGGGCGCAATTGATGGTACGGGGCTTGCGTGACGGCACCGACCTTGATTACGAAATGCAGATGGC
TGGCATGAACGGCACCATGGCGCCGGAATTGCAGACGGTTTTTCTACCTGCCGATCCGGCAGTGCGCACGATTACCGCCA
CATTGGTTCGCCAGATTGCGTCCATGGGCGGGGACATCAAGCCCTTCGTTCCGGTGGCCGTCGCTGCCGCCTTGAACACC
AAATTCAAATCCTGA

Upstream 100 bases:

>100_bases
AGATGCTGTTCATATCGCGTTCATTTGTTTTCTTGGTTTCTGTTTTCTTATCGCTGCTGTTCTTGTTGAAAATCCCGTCA
GAAAAGGCTAGCTGGAAGAA

Downstream 100 bases:

>100_bases
CCGCAGGGAGTTTTTCGATCATGTCTTTCATTCGCTCGGCGCTGGCCGCTGCCGCTTTTGTCGCGCTCTCGATCGGTGCA
GTGCAGACCGCATCGGCTGC

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MTIAIYAGSFDPVTNGHIDVLKGALRLADQVIVAIGMHPGKKPLFSFDERVALIEASAKAVLHKDAARVSVIAFDGLVID
AARKHGAQLMVRGLRDGTDLDYEMQMAGMNGTMAPELQTVFLPADPAVRTITATLVRQIASMGGDIKPFVPVAVAAALNT
KFKS

Sequences:

>Translated_164_residues
MTIAIYAGSFDPVTNGHIDVLKGALRLADQVIVAIGMHPGKKPLFSFDERVALIEASAKAVLHKDAARVSVIAFDGLVID
AARKHGAQLMVRGLRDGTDLDYEMQMAGMNGTMAPELQTVFLPADPAVRTITATLVRQIASMGGDIKPFVPVAVAAALNT
KFKS
>Mature_163_residues
TIAIYAGSFDPVTNGHIDVLKGALRLADQVIVAIGMHPGKKPLFSFDERVALIEASAKAVLHKDAARVSVIAFDGLVIDA
ARKHGAQLMVRGLRDGTDLDYEMQMAGMNGTMAPELQTVFLPADPAVRTITATLVRQIASMGGDIKPFVPVAVAAALNTK
FKS

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=159, Percent_Identity=42.7672955974843, Blast_Score=134, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_BRUA1 (B2S5U8)

Other databases:

- EMBL:   CP000887
- RefSeq:   YP_001935019.1
- ProteinModelPortal:   B2S5U8
- SMR:   B2S5U8
- GeneID:   6328587
- GenomeReviews:   CP000887_GR
- KEGG:   bmc:BAbS19_I10380
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17400; Mature: 17268

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAIYAGSFDPVTNGHIDVLKGALRLADQVIVAIGMHPGKKPLFSFDERVALIEASAKA
CEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCEEEEHHHHHH
VLHKDAARVSVIAFDGLVIDAARKHGAQLMVRGLRDGTDLDYEMQMAGMNGTMAPELQTV
HHHCCCCEEEEEEECCEEEEHHHHCCHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEE
FLPADPAVRTITATLVRQIASMGGDIKPFVPVAVAAALNTKFKS
EECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TIAIYAGSFDPVTNGHIDVLKGALRLADQVIVAIGMHPGKKPLFSFDERVALIEASAKA
EEEEEECCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCEEEEHHHHHH
VLHKDAARVSVIAFDGLVIDAARKHGAQLMVRGLRDGTDLDYEMQMAGMNGTMAPELQTV
HHHCCCCEEEEEEECCEEEEHHHHCCHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEE
FLPADPAVRTITATLVRQIASMGGDIKPFVPVAVAAALNTKFKS
EECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA