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The map label for this gene is gpt

Identifier: 23501924

GI number: 23501924

Start: 1015900

End: 1016397

Strand: Reverse

Name: gpt

Synonym: BR1046

Alternate gene names: 23501924

Gene position: 1016397-1015900 (Counterclockwise)

Preceding gene: 23501925

Following gene: 23501923

Centisome position: 48.22

GC content: 58.03

Gene sequence:

>498_bases
ATGTCCTTGCCCGATAAAGCCTTTCCCGTTTCCTGGGATCAGTTTCACCGCGATGCCCGCGCCCTCGCCTGGCGAATTGC
CGGTCTGGATCGTGAATGGCGCGCCATCGTAGCGATCACGCGCGGAGGGCTCGTGCCGGCTGCCATCATCTGCCGCGAAC
TGGGTATCCGCCTCATTGAAACCGTCTGCATCGCTTCCTATCACGATTACACGTCACAGGGCGAAATGCAGGTTCTCAAA
GGGATCGGAGCATCTCTTCTGGAAAATCAGGGTGAAGGCGTCATTGTGGTGGACGACCTGACCGACACAGGCAAGACCGC
CGCAATCGTGCGCGAGATGATGCCGCGCGCGCATTTTGCCACCGTATATGCAAAGCCGAAGGGCCGTCCGCTTATCGACA
CCTTCGTCACGGAGGTCTCACAGGATACCTGGATCTATTTCCCATGGGATATGGGCTTCACCTATCAGGAGCCGATTGCT
GGCGGAAAACGCGGCTAA

Upstream 100 bases:

>100_bases
ACAGTTGGCGCGAATGACGGCATGTCATCGCAGATTTTTGGTTTTTTGCAGGTCCGCAGGGCGCAACCCCACGCCACGGA
TCGATCCATGGAGCGTTTCG

Downstream 100 bases:

>100_bases
ATGAAACCAAATGAACGCGATTGCGGTGATATTTCCGCCGCAATCGCGCCTTATGGAAAGGATGCCGAGAGAGCATCATT
TGCAGGATAAAGGCTTTCAT

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MSLPDKAFPVSWDQFHRDARALAWRIAGLDREWRAIVAITRGGLVPAAIICRELGIRLIETVCIASYHDYTSQGEMQVLK
GIGASLLENQGEGVIVVDDLTDTGKTAAIVREMMPRAHFATVYAKPKGRPLIDTFVTEVSQDTWIYFPWDMGFTYQEPIA
GGKRG

Sequences:

>Translated_165_residues
MSLPDKAFPVSWDQFHRDARALAWRIAGLDREWRAIVAITRGGLVPAAIICRELGIRLIETVCIASYHDYTSQGEMQVLK
GIGASLLENQGEGVIVVDDLTDTGKTAAIVREMMPRAHFATVYAKPKGRPLIDTFVTEVSQDTWIYFPWDMGFTYQEPIA
GGKRG
>Mature_164_residues
SLPDKAFPVSWDQFHRDARALAWRIAGLDREWRAIVAITRGGLVPAAIICRELGIRLIETVCIASYHDYTSQGEMQVLKG
IGASLLENQGEGVIVVDDLTDTGKTAAIVREMMPRAHFATVYAKPKGRPLIDTFVTEVSQDTWIYFPWDMGFTYQEPIAG
GKRG

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily

Homologues:

Organism=Escherichia coli, GI1786433, Length=156, Percent_Identity=51.2820512820513, Blast_Score=165, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XGPT_BRUC2 (A9MB59)

Other databases:

- EMBL:   CP000872
- RefSeq:   YP_001592883.1
- ProteinModelPortal:   A9MB59
- SMR:   A9MB59
- GeneID:   5784359
- GenomeReviews:   CP000872_GR
- KEGG:   bcs:BCAN_A1060
- HOGENOM:   HBG503428
- OMA:   LVDTFIT
- ProtClustDB:   PRK09177
- BioCyc:   BCAN483179:BCAN_A1060-MONOMER
- HAMAP:   MF_01903
- InterPro:   IPR000836

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 18370; Mature: 18239

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 102-102 BINDING 145-145

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPDKAFPVSWDQFHRDARALAWRIAGLDREWRAIVAITRGGLVPAAIICRELGIRLIE
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
TVCIASYHDYTSQGEMQVLKGIGASLLENQGEGVIVVDDLTDTGKTAAIVREMMPRAHFA
HHHHHHHCCCCCCCHHHHHHHCCHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEE
TVYAKPKGRPLIDTFVTEVSQDTWIYFPWDMGFTYQEPIAGGKRG
EEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SLPDKAFPVSWDQFHRDARALAWRIAGLDREWRAIVAITRGGLVPAAIICRELGIRLIE
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
TVCIASYHDYTSQGEMQVLKGIGASLLENQGEGVIVVDDLTDTGKTAAIVREMMPRAHFA
HHHHHHHCCCCCCCHHHHHHHCCHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEE
TVYAKPKGRPLIDTFVTEVSQDTWIYFPWDMGFTYQEPIAGGKRG
EEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA