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The map label for this gene is erpA2 [H]

Identifier: 23501761

GI number: 23501761

Start: 846045

End: 846371

Strand: Reverse

Name: erpA2 [H]

Synonym: BR0875

Alternate gene names: 23501761

Gene position: 846371-846045 (Counterclockwise)

Preceding gene: 23501775

Following gene: 23501759

Centisome position: 40.15

GC content: 54.74

Gene sequence:

>327_bases
ATGACAGGCATTACCGTTTCAGATTCCGCTGCCAGGCGGATCGCCAAAATTCTCGATTCGGAGCCGGGAAAGACCGCGCT
TCGCGTTTCTGTCGAAGGTGGCGGCTGCTCCGGCTTTTCCTATAAATATGACCTCGTCGACGCACAGACCGAGGATGACA
TCGTCATCGAAAAACTCGGCGCCAGAGTGCTGATTGATTCCATCTCCGTGCCTTATATGGACGGCTCTGAAATTGATTTC
GTCGATGATCTGATGGGGCAATCATTCCAGATCCGCAACCCCAATGCGACCGCTTCCTGCGGCTGCGGCACCAGCTTCGC
GATCTGA

Upstream 100 bases:

>100_bases
GTTCATAGCTATCAGCTAAACATGAAGGCAAGTACGCGGCTATCGGAAAATCTCAAGAACGCATAACCCGATCCCCGTCC
CTGCAAACGGAACAAGGCAA

Downstream 100 bases:

>100_bases
GCGGCGCACCAAAACCCGTGATGCAAAACCGGCGGCCAGATGGCCGCCGTTTTTTTAACCATGGCAACAAGCGGACAGTT
TCAGACTTTCACTGAAGCAA

Product: HesB/YadR/YfhF family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 108; Mature: 107

Protein sequence:

>108_residues
MTGITVSDSAARRIAKILDSEPGKTALRVSVEGGGCSGFSYKYDLVDAQTEDDIVIEKLGARVLIDSISVPYMDGSEIDF
VDDLMGQSFQIRNPNATASCGCGTSFAI

Sequences:

>Translated_108_residues
MTGITVSDSAARRIAKILDSEPGKTALRVSVEGGGCSGFSYKYDLVDAQTEDDIVIEKLGARVLIDSISVPYMDGSEIDF
VDDLMGQSFQIRNPNATASCGCGTSFAI
>Mature_107_residues
TGITVSDSAARRIAKILDSEPGKTALRVSVEGGGCSGFSYKYDLVDAQTEDDIVIEKLGARVLIDSISVPYMDGSEIDFV
DDLMGQSFQIRNPNATASCGCGTSFAI

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=106, Percent_Identity=44.3396226415094, Blast_Score=94, Evalue=3e-20,
Organism=Homo sapiens, GI52426768, Length=106, Percent_Identity=32.0754716981132, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788877, Length=105, Percent_Identity=40.9523809523809, Blast_Score=94, Evalue=2e-21,
Organism=Escherichia coli, GI1787974, Length=106, Percent_Identity=36.7924528301887, Blast_Score=94, Evalue=3e-21,
Organism=Escherichia coli, GI1786351, Length=106, Percent_Identity=38.6792452830189, Blast_Score=91, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71998452, Length=107, Percent_Identity=41.1214953271028, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI193209025, Length=105, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25146411, Length=105, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323001, Length=105, Percent_Identity=35.2380952380952, Blast_Score=79, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6325324, Length=129, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24649697, Length=106, Percent_Identity=40.5660377358491, Blast_Score=82, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24642263, Length=106, Percent_Identity=33.0188679245283, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 11431; Mature: 11300

Theoretical pI: Translated: 4.10; Mature: 4.10

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGITVSDSAARRIAKILDSEPGKTALRVSVEGGGCSGFSYKYDLVDAQTEDDIVIEKLG
CCCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCHHHHHCC
ARVLIDSISVPYMDGSEIDFVDDLMGQSFQIRNPNATASCGCGTSFAI
CEEEEECCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TGITVSDSAARRIAKILDSEPGKTALRVSVEGGGCSGFSYKYDLVDAQTEDDIVIEKLG
CCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCCHHHHHCC
ARVLIDSISVPYMDGSEIDFVDDLMGQSFQIRNPNATASCGCGTSFAI
CEEEEECCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA