Click here to switch to the map view.

The map label for this gene is sugE [H]

Identifier: 23501667

GI number: 23501667

Start: 763971

End: 764288

Strand: Reverse

Name: sugE [H]

Synonym: BR0780

Alternate gene names: 23501667

Gene position: 764288-763971 (Counterclockwise)

Preceding gene: 23501668

Following gene: 23501662

Centisome position: 36.26

GC content: 52.52

Gene sequence:

>318_bases
ATGGCATGGATCTATCTGGTATTCGCAGGCATTTTTGAGGTTGTCTGGGCTTTTTTCATGAAAAAGTCCGAGGGTTTTTC
CCTTCTCACACCCACGATCATAACTTTCGTGACCATGATGGGCAGTTTCCTGCTGCTTGCCATCGCAATGCGCAGCCTGC
CGCTTGGCACCGCCTATGCTATATGGACCGGGATCGGCGCGGTGGGTGCATTCATCGTCGGTATATTCCTGCTTGGCGAA
GCGGCAACCTTCTTCCGCGTGGCCAGCGTCGCGCTTATTCTTGCAGGCATTATCGGACTGAAACTGTCTTCCACATAA

Upstream 100 bases:

>100_bases
GGGTCAAGGGGTCGTGGGTTCGAATCCCGCCGCTCCGACCATTTTCTTCCCCTTATTTCCCCAGATTGCCTGCCCCCCTT
TTCACCAAATGAGCTTTAAA

Downstream 100 bases:

>100_bases
AATGCAAAAAGGGAGGCATCAGCCTCCCTTCATTCAATCTGCATAATATTCAGCGAACCTGATCCAGAAGCCGCTTGCAT
TCCAGAAGGTCAAAAAGGGC

Product: sugE protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 105; Mature: 104

Protein sequence:

>105_residues
MAWIYLVFAGIFEVVWAFFMKKSEGFSLLTPTIITFVTMMGSFLLLAIAMRSLPLGTAYAIWTGIGAVGAFIVGIFLLGE
AATFFRVASVALILAGIIGLKLSST

Sequences:

>Translated_105_residues
MAWIYLVFAGIFEVVWAFFMKKSEGFSLLTPTIITFVTMMGSFLLLAIAMRSLPLGTAYAIWTGIGAVGAFIVGIFLLGE
AATFFRVASVALILAGIIGLKLSST
>Mature_104_residues
AWIYLVFAGIFEVVWAFFMKKSEGFSLLTPTIITFVTMMGSFLLLAIAMRSLPLGTAYAIWTGIGAVGAFIVGIFLLGEA
ATFFRVASVALILAGIIGLKLSST

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=104, Percent_Identity=64.4230769230769, Blast_Score=126, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11233; Mature: 11102

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWIYLVFAGIFEVVWAFFMKKSEGFSLLTPTIITFVTMMGSFLLLAIAMRSLPLGTAYA
CHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
IWTGIGAVGAFIVGIFLLGEAATFFRVASVALILAGIIGLKLSST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AWIYLVFAGIFEVVWAFFMKKSEGFSLLTPTIITFVTMMGSFLLLAIAMRSLPLGTAYA
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
IWTGIGAVGAFIVGIFLLGEAATFFRVASVALILAGIIGLKLSST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]