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The map label for this gene is siaT [H]

Identifier: 23100710

GI number: 23100710

Start: 3391470

End: 3392744

Strand: Reverse

Name: siaT [H]

Synonym: OB3255

Alternate gene names: 23100710

Gene position: 3392744-3391470 (Counterclockwise)

Preceding gene: 23100711

Following gene: 23100709

Centisome position: 93.45

GC content: 36.55

Gene sequence:

>1275_bases
ATGATACTTGTATTAGTTCTATCGTTAATTGTTCTATTTATTATCGGTGTACCTGTGGCAATTTCATTAGGGTTATCTTC
TAGTCTGGCGATATTAGTAGCTGGAGACATACCGTTGTTAACATTGGCACAACGTGCTTTTGTCTCACTTGATTCTTTCC
CTTTACTAGCGATTCCGTTGTTTATACTTGCGGGTGCTTTAATGGAATATGGGGGGATATCACAACGATTAATAAACTTG
GCTAATGCAATTACTGGTCATGTACCAGGAGGCTTAGCGATTGTAACTGTAGTAACCACGATGTTCTTTGCTGCTATATC
AGGATCAAGTGTAGCCGCAACTGCGGCGCTTGGCGCAATCTTGATTCCAGCGATGATTAATCGAGGTTATGATAAAGAAT
TTGCAGGTGGAGTACAGGCTGTTTCTGGAACGTTAGGAATTATAATACCACCGAGTATACCTTTAATATTGTATGGGACA
GCTGTCGGGGCATCTATTGGAGATTTATTTATCGCCGGAATGGTACCAGGAATCATCATTGGTATTGGACTCGTTGTAAC
GGTGTATATATTGGCTAAAAAGCGTAATTATTTAAAAGAACCAAAGAAATCAAGCAAAGATATTGGCAAAGCATTCTTAG
AAGCAATTCCAGCATTAATCATGCCAATTATCATTCTAGGCGGAATATATAGTGGAATATTTACTGCCACTGAAGCTGCT
GGTGTTGCGGTTGCTTATGCATTTATCGTTAGTGTTTTCGTTTACAAAGCAATTAATAAAGTAAACATAAAAGAAATATT
AACCCAAGCATCTGTAACAACTTCTACCATTATGTTTATTCTTGCTACGGCTGGATTATTTAGCTGGATACTAACAATTG
AAAATATACCGCAACAGGTTGCTAGTCTAATAACATCTATTTCAGATAGTCCGATGGTATTCTTAACTATAGTTATTCTA
GTACTTTTACTTGTGGGTATGTTTATGGAGACAAACGCTTCTATTATCATTTTAGCTCCTATTCTTGTGCCGGTTGCTGT
AGAACTCGGATTAGACCCAGTTCATTTTGGTATTGTTATGATCGTTACATTAGCGATTGGTATGGTAACACCACCATTAG
GGTTGAATCTATTTGTAGTATCAAAAATAGGAAAAGTACGTATTGATCATTTAACAAAAGGGTTAATTCCTTTCTATATT
GCTATTTTAATTAGCTTAATCGTTATAACATATATCCCTTCCATAACAATGAGCCTAGTGGAATGGATGAAATAA

Upstream 100 bases:

>100_bases
CAATACCACTTGGTTCGCTTCTTATGTTGTGTAATATTATTGCATTGTTAATAAGTCCACCTGAAGATGATGATTCGAAG
GAAACGGTAGGTGACTTACT

Downstream 100 bases:

>100_bases
ATAAAGGAAGTGAATAAATGGATAATCAGCTATTAAGTCAATTAAGCTCAACTGGAAAATTTATGATGGATAAAGACCTT
GCCTGGGGTACTGCGGGCAA

Product: C4-dicarboxylate transport system permease large protein

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MILVLVLSLIVLFIIGVPVAISLGLSSSLAILVAGDIPLLTLAQRAFVSLDSFPLLAIPLFILAGALMEYGGISQRLINL
ANAITGHVPGGLAIVTVVTTMFFAAISGSSVAATAALGAILIPAMINRGYDKEFAGGVQAVSGTLGIIIPPSIPLILYGT
AVGASIGDLFIAGMVPGIIIGIGLVVTVYILAKKRNYLKEPKKSSKDIGKAFLEAIPALIMPIIILGGIYSGIFTATEAA
GVAVAYAFIVSVFVYKAINKVNIKEILTQASVTTSTIMFILATAGLFSWILTIENIPQQVASLITSISDSPMVFLTIVIL
VLLLVGMFMETNASIIILAPILVPVAVELGLDPVHFGIVMIVTLAIGMVTPPLGLNLFVVSKIGKVRIDHLTKGLIPFYI
AILISLIVITYIPSITMSLVEWMK

Sequences:

>Translated_424_residues
MILVLVLSLIVLFIIGVPVAISLGLSSSLAILVAGDIPLLTLAQRAFVSLDSFPLLAIPLFILAGALMEYGGISQRLINL
ANAITGHVPGGLAIVTVVTTMFFAAISGSSVAATAALGAILIPAMINRGYDKEFAGGVQAVSGTLGIIIPPSIPLILYGT
AVGASIGDLFIAGMVPGIIIGIGLVVTVYILAKKRNYLKEPKKSSKDIGKAFLEAIPALIMPIIILGGIYSGIFTATEAA
GVAVAYAFIVSVFVYKAINKVNIKEILTQASVTTSTIMFILATAGLFSWILTIENIPQQVASLITSISDSPMVFLTIVIL
VLLLVGMFMETNASIIILAPILVPVAVELGLDPVHFGIVMIVTLAIGMVTPPLGLNLFVVSKIGKVRIDHLTKGLIPFYI
AILISLIVITYIPSITMSLVEWMK
>Mature_424_residues
MILVLVLSLIVLFIIGVPVAISLGLSSSLAILVAGDIPLLTLAQRAFVSLDSFPLLAIPLFILAGALMEYGGISQRLINL
ANAITGHVPGGLAIVTVVTTMFFAAISGSSVAATAALGAILIPAMINRGYDKEFAGGVQAVSGTLGIIIPPSIPLILYGT
AVGASIGDLFIAGMVPGIIIGIGLVVTVYILAKKRNYLKEPKKSSKDIGKAFLEAIPALIMPIIILGGIYSGIFTATEAA
GVAVAYAFIVSVFVYKAINKVNIKEILTQASVTTSTIMFILATAGLFSWILTIENIPQQVASLITSISDSPMVFLTIVIL
VLLLVGMFMETNASIIILAPILVPVAVELGLDPVHFGIVMIVTLAIGMVTPPLGLNLFVVSKIGKVRIDHLTKGLIPFYI
AILISLIVITYIPSITMSLVEWMK

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=410, Percent_Identity=37.3170731707317, Blast_Score=258, Evalue=4e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 44418; Mature: 44418

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVLVLSLIVLFIIGVPVAISLGLSSSLAILVAGDIPLLTLAQRAFVSLDSFPLLAIPL
CHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHH
FILAGALMEYGGISQRLINLANAITGHVPGGLAIVTVVTTMFFAAISGSSVAATAALGAI
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LIPAMINRGYDKEFAGGVQAVSGTLGIIIPPSIPLILYGTAVGASIGDLFIAGMVPGIII
HHHHHHCCCCCHHHHCCHHHHCCCEEEEECCCCCEEEEEHHHCCHHHHHHHHHHHHHHHH
GIGLVVTVYILAKKRNYLKEPKKSSKDIGKAFLEAIPALIMPIIILGGIYSGIFTATEAA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVAVAYAFIVSVFVYKAINKVNIKEILTQASVTTSTIMFILATAGLFSWILTIENIPQQV
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASLITSISDSPMVFLTIVILVLLLVGMFMETNASIIILAPILVPVAVELGLDPVHFGIVM
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCHHHHHHHH
IVTLAIGMVTPPLGLNLFVVSKIGKVRIDHLTKGLIPFYIAILISLIVITYIPSITMSLV
HHHHHHHHCCCCCCCCCCEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EWMK
HHHC
>Mature Secondary Structure
MILVLVLSLIVLFIIGVPVAISLGLSSSLAILVAGDIPLLTLAQRAFVSLDSFPLLAIPL
CHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHH
FILAGALMEYGGISQRLINLANAITGHVPGGLAIVTVVTTMFFAAISGSSVAATAALGAI
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LIPAMINRGYDKEFAGGVQAVSGTLGIIIPPSIPLILYGTAVGASIGDLFIAGMVPGIII
HHHHHHCCCCCHHHHCCHHHHCCCEEEEECCCCCEEEEEHHHCCHHHHHHHHHHHHHHHH
GIGLVVTVYILAKKRNYLKEPKKSSKDIGKAFLEAIPALIMPIIILGGIYSGIFTATEAA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVAVAYAFIVSVFVYKAINKVNIKEILTQASVTTSTIMFILATAGLFSWILTIENIPQQV
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASLITSISDSPMVFLTIVILVLLLVGMFMETNASIIILAPILVPVAVELGLDPVHFGIVM
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCHHHHHHHH
IVTLAIGMVTPPLGLNLFVVSKIGKVRIDHLTKGLIPFYIAILISLIVITYIPSITMSLV
HHHHHHHHCCCCCCCCCCEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EWMK
HHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]