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The map label for this gene is caiD [C]

Identifier: 23100123

GI number: 23100123

Start: 2737711

End: 2738493

Strand: Reverse

Name: caiD [C]

Synonym: OB2668

Alternate gene names: 23100123

Gene position: 2738493-2737711 (Counterclockwise)

Preceding gene: 23100124

Following gene: 23100122

Centisome position: 75.43

GC content: 37.29

Gene sequence:

>783_bases
GTGACAATGACATCTGCGGTTCGTTATCAAAAGGAAAATCAAATAGCTTATATAGCAATGAATCGACCAGAAAAACGAAA
TGCATTATCGATAGAAATGGCAGAAGAATTAATAGCAGCACTACATCAGGCAGAGAAAGATTCAGAGGTGAAGGTAGTAA
TTTTAACCGGTGAAGGAAAAGGTTTCTCTGCTGGAGGGGATCTACAAGTACTGCATTCATTAAATAATTCCGCTCAAATT
ATGAATTATATGAAGAAAGCACTGCAAATTATTCAAACGATGCGGGACTTAGATAAATATGTAATCAGTGCTGTGCATGG
ATTTGCAGCAGGAGCGGGATTTAGCATTGCAATTGCAGCCGATTTTATAGTAGCAAAGAAAGATGCTAGTTTTGCTTGTA
GTTTTACAAATGTAGGTATTATCCCGGATTTAGGTCTTTTAAAAGGTCTTGCTGATAAACTACCAACAGCTGTTGCAAAA
GAGTGGATTTCATCCGGAAGGCATATTACTGCACAAGAAGCTTATGAGCGAGGAATAGTAAATCGTGTAGTAGAAGGAGA
TCTATTAGAAGAAGCGACGGATTTTGCACAATTTATTGTACAAGGTCCGCCATTAGCTAATCAATTTGTTAAGCACATGG
TGAATCATGCTAGTGAATACAACCAGGATACGAATGATCTACAAGAATTAGCGGTACAAACCTTACTTTTACAGTCAGAA
GATAATAAAGAGGGAATTGCAGCCTTCTTTGAAAAAAGAAAACCTGCTTTTAAAGGGAAGTAA

Upstream 100 bases:

>100_bases
ACAGTCAATTCAACAAGTAGTTAATGAACTTCAGCAACAATATGAGCAAGCCAAAAACAAAAACGAAATTGCTATTAAGT
AAAAGTAAGGGGTGGAAAAA

Downstream 100 bases:

>100_bases
AAGGAGAGGTCCGTAATGAATTTATCTATTTCTTCATCGGAACAGGCAGAACTAGATTTATTAAGACGTAGCGTGGAGAC
TTTTTGCAAACAGGAGGTCA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MTMTSAVRYQKENQIAYIAMNRPEKRNALSIEMAEELIAALHQAEKDSEVKVVILTGEGKGFSAGGDLQVLHSLNNSAQI
MNYMKKALQIIQTMRDLDKYVISAVHGFAAGAGFSIAIAADFIVAKKDASFACSFTNVGIIPDLGLLKGLADKLPTAVAK
EWISSGRHITAQEAYERGIVNRVVEGDLLEEATDFAQFIVQGPPLANQFVKHMVNHASEYNQDTNDLQELAVQTLLLQSE
DNKEGIAAFFEKRKPAFKGK

Sequences:

>Translated_260_residues
MTMTSAVRYQKENQIAYIAMNRPEKRNALSIEMAEELIAALHQAEKDSEVKVVILTGEGKGFSAGGDLQVLHSLNNSAQI
MNYMKKALQIIQTMRDLDKYVISAVHGFAAGAGFSIAIAADFIVAKKDASFACSFTNVGIIPDLGLLKGLADKLPTAVAK
EWISSGRHITAQEAYERGIVNRVVEGDLLEEATDFAQFIVQGPPLANQFVKHMVNHASEYNQDTNDLQELAVQTLLLQSE
DNKEGIAAFFEKRKPAFKGK
>Mature_259_residues
TMTSAVRYQKENQIAYIAMNRPEKRNALSIEMAEELIAALHQAEKDSEVKVVILTGEGKGFSAGGDLQVLHSLNNSAQIM
NYMKKALQIIQTMRDLDKYVISAVHGFAAGAGFSIAIAADFIVAKKDASFACSFTNVGIIPDLGLLKGLADKLPTAVAKE
WISSGRHITAQEAYERGIVNRVVEGDLLEEATDFAQFIVQGPPLANQFVKHMVNHASEYNQDTNDLQELAVQTLLLQSED
NKEGIAAFFEKRKPAFKGK

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=249, Percent_Identity=32.9317269076305, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI31542718, Length=250, Percent_Identity=32.8, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI70995211, Length=266, Percent_Identity=27.0676691729323, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4502327, Length=263, Percent_Identity=30.7984790874525, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI68989263, Length=215, Percent_Identity=26.9767441860465, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI37594469, Length=194, Percent_Identity=27.319587628866, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI37594471, Length=194, Percent_Identity=27.319587628866, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI45643119, Length=181, Percent_Identity=29.2817679558011, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI260275230, Length=181, Percent_Identity=29.2817679558011, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI260274832, Length=181, Percent_Identity=29.2817679558011, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI157694516, Length=222, Percent_Identity=27.4774774774775, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI213417737, Length=222, Percent_Identity=27.4774774774775, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI25453481, Length=181, Percent_Identity=29.8342541436464, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4757966, Length=181, Percent_Identity=29.8342541436464, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI51538573, Length=181, Percent_Identity=29.8342541436464, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI51538581, Length=181, Percent_Identity=29.8342541436464, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4757968, Length=191, Percent_Identity=29.3193717277487, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI49355787, Length=191, Percent_Identity=29.3193717277487, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI20127408, Length=183, Percent_Identity=24.0437158469945, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI221142681, Length=266, Percent_Identity=35.7142857142857, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1787659, Length=251, Percent_Identity=33.0677290836653, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1787660, Length=256, Percent_Identity=32.421875, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87082183, Length=252, Percent_Identity=31.3492063492063, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1788597, Length=268, Percent_Identity=29.8507462686567, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1788682, Length=244, Percent_Identity=26.6393442622951, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790281, Length=183, Percent_Identity=27.3224043715847, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=252, Percent_Identity=33.7301587301587, Blast_Score=127, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI25145438, Length=261, Percent_Identity=34.4827586206897, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17534483, Length=258, Percent_Identity=30.2325581395349, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17560910, Length=259, Percent_Identity=27.4131274131274, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17536985, Length=243, Percent_Identity=27.5720164609054, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17540714, Length=219, Percent_Identity=28.310502283105, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17540306, Length=256, Percent_Identity=28.125, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17535521, Length=256, Percent_Identity=24.21875, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17558304, Length=225, Percent_Identity=24.4444444444444, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25144157, Length=179, Percent_Identity=27.9329608938547, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI25144160, Length=179, Percent_Identity=27.9329608938547, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17549921, Length=191, Percent_Identity=25.6544502617801, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=190, Percent_Identity=24.7368421052632, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129971, Length=246, Percent_Identity=32.520325203252, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24653477, Length=246, Percent_Identity=32.520325203252, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24653139, Length=252, Percent_Identity=30.1587301587302, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI19922422, Length=257, Percent_Identity=26.8482490272374, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI19920382, Length=263, Percent_Identity=29.277566539924, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24650670, Length=199, Percent_Identity=30.6532663316583, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21357171, Length=257, Percent_Identity=26.0700389105058, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24654903, Length=185, Percent_Identity=25.9459459459459, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI19921018, Length=213, Percent_Identity=23.943661971831, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 28489; Mature: 28358

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMTSAVRYQKENQIAYIAMNRPEKRNALSIEMAEELIAALHQAEKDSEVKVVILTGEGK
CCCCHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
GFSAGGDLQVLHSLNNSAQIMNYMKKALQIIQTMRDLDKYVISAVHGFAAGAGFSIAIAA
CCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHH
DFIVAKKDASFACSFTNVGIIPDLGLLKGLADKLPTAVAKEWISSGRHITAQEAYERGIV
HHHHEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
NRVVEGDLLEEATDFAQFIVQGPPLANQFVKHMVNHASEYNQDTNDLQELAVQTLLLQSE
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
DNKEGIAAFFEKRKPAFKGK
CCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TMTSAVRYQKENQIAYIAMNRPEKRNALSIEMAEELIAALHQAEKDSEVKVVILTGEGK
CCCHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
GFSAGGDLQVLHSLNNSAQIMNYMKKALQIIQTMRDLDKYVISAVHGFAAGAGFSIAIAA
CCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHH
DFIVAKKDASFACSFTNVGIIPDLGLLKGLADKLPTAVAKEWISSGRHITAQEAYERGIV
HHHHEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
NRVVEGDLLEEATDFAQFIVQGPPLANQFVKHMVNHASEYNQDTNDLQELAVQTLLLQSE
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
DNKEGIAAFFEKRKPAFKGK
CCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA