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The map label for this gene is mmgC [H]

Identifier: 23100122

GI number: 23100122

Start: 2736529

End: 2737695

Strand: Reverse

Name: mmgC [H]

Synonym: OB2667

Alternate gene names: 23100122

Gene position: 2737695-2736529 (Counterclockwise)

Preceding gene: 23100123

Following gene: 23100121

Centisome position: 75.41

GC content: 39.59

Gene sequence:

>1167_bases
ATGAATTTATCTATTTCTTCATCGGAACAGGCAGAACTAGATTTATTAAGACGTAGCGTGGAGACTTTTTGCAAACAGGA
GGTCACCCCATATTATACGAACTGGGAAGAACAAGGAATGGTTCCGAGACAATTTTGGAATAAGCTTGGAGAACAAGGAT
TTTTACTTCCAGAAGTACCAGAAGAATATGGAGGTCTTGGTGCAAGCTTTCTTTATTCGACAACAATAATAGAGTCGTTT
TGTCGACAGGGATATAGCTCGATCGCAGCAAATCTATCCGTACATGATACGATACTAGCAAACTATTTCTTGCAATATGG
AACCGAAGAACAAAAGAAATATTACTTGCCGAGAATGATTTCAGGTGAATTAGTTGGTGCAATTGCAATGACTGAGCCGG
GGGCGGGGAGTGACCTTCAACGGATAAAAACCACAGCCAATTTTGATGAAGGCTTAAATGGCTATGTTTTAAATGGTTCA
AAAACATTTATTACGAACGGCCAGCATTGTGACTTTGCAATTGTTGTGGCGAAAACGAAAGTGGATGTAAAACCATCAAA
AGGTATATCGCTATTTATCGTTGACGCAAAGAAGAATGGTTTTACTAAAGGAAAAAATCTTGAAAAAATAGGACTACATG
CTTGTGATACGTCTGAATTATATTTTGAAGATATTCTTTTAGATGAGTCTGATATTCTTGGAGGAGTAAATCAAGGCTTT
TCCGTGTTAATGAACGAATTACCTCGGGAACGGTTGATTGTTGCCAATTGTGCTGTTGCCTCCATGGAAGGCGTACTTAC
TGACACGGTGAGCTATGTGAAGGAGCGAGAGTTATTCGGAACAACCCTTGATCAATTCCAGCATACGCAATTTACATTGG
CTGAATTACAAACCAAAGTACGTGTCCAACGGTCTTTTGCCGATGAATGTACAACAAGGTGTATAGAAGGGAATTTAGAC
ACTGCTACAGCTAGTATGGCAAAACTAAGTTGTACTGAAGTTCAAGGTGAAGTGATTGATCGGTGTCTGCAGTTATTTGG
AGGATATGGCTATATGCTAGAGTACCCTATAGCTCGAGCTTATGCGGATGCTCGAGTTCAACGGATTTATGGCGGTACAT
CGGAAGTGATGAAGCTAATTATTAGTAGAGAATTGTTGTCAAAGTAA

Upstream 100 bases:

>100_bases
AACCTTACTTTTACAGTCAGAAGATAATAAAGAGGGAATTGCAGCCTTCTTTGAAAAAAGAAAACCTGCTTTTAAAGGGA
AGTAAAAGGAGAGGTCCGTA

Downstream 100 bases:

>100_bases
CTGTTTTTAAGTGAGAAGAATGAAACAAATCTTACTATAAGGGAGTTGTTTGCAAATGCTAGCACCACTAACCCCACTAG
ATTGGAAACGTAGAGCTATC

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNLSISSSEQAELDLLRRSVETFCKQEVTPYYTNWEEQGMVPRQFWNKLGEQGFLLPEVPEEYGGLGASFLYSTTIIESF
CRQGYSSIAANLSVHDTILANYFLQYGTEEQKKYYLPRMISGELVGAIAMTEPGAGSDLQRIKTTANFDEGLNGYVLNGS
KTFITNGQHCDFAIVVAKTKVDVKPSKGISLFIVDAKKNGFTKGKNLEKIGLHACDTSELYFEDILLDESDILGGVNQGF
SVLMNELPRERLIVANCAVASMEGVLTDTVSYVKERELFGTTLDQFQHTQFTLAELQTKVRVQRSFADECTTRCIEGNLD
TATASMAKLSCTEVQGEVIDRCLQLFGGYGYMLEYPIARAYADARVQRIYGGTSEVMKLIISRELLSK

Sequences:

>Translated_388_residues
MNLSISSSEQAELDLLRRSVETFCKQEVTPYYTNWEEQGMVPRQFWNKLGEQGFLLPEVPEEYGGLGASFLYSTTIIESF
CRQGYSSIAANLSVHDTILANYFLQYGTEEQKKYYLPRMISGELVGAIAMTEPGAGSDLQRIKTTANFDEGLNGYVLNGS
KTFITNGQHCDFAIVVAKTKVDVKPSKGISLFIVDAKKNGFTKGKNLEKIGLHACDTSELYFEDILLDESDILGGVNQGF
SVLMNELPRERLIVANCAVASMEGVLTDTVSYVKERELFGTTLDQFQHTQFTLAELQTKVRVQRSFADECTTRCIEGNLD
TATASMAKLSCTEVQGEVIDRCLQLFGGYGYMLEYPIARAYADARVQRIYGGTSEVMKLIISRELLSK
>Mature_388_residues
MNLSISSSEQAELDLLRRSVETFCKQEVTPYYTNWEEQGMVPRQFWNKLGEQGFLLPEVPEEYGGLGASFLYSTTIIESF
CRQGYSSIAANLSVHDTILANYFLQYGTEEQKKYYLPRMISGELVGAIAMTEPGAGSDLQRIKTTANFDEGLNGYVLNGS
KTFITNGQHCDFAIVVAKTKVDVKPSKGISLFIVDAKKNGFTKGKNLEKIGLHACDTSELYFEDILLDESDILGGVNQGF
SVLMNELPRERLIVANCAVASMEGVLTDTVSYVKERELFGTTLDQFQHTQFTLAELQTKVRVQRSFADECTTRCIEGNLD
TATASMAKLSCTEVQGEVIDRCLQLFGGYGYMLEYPIARAYADARVQRIYGGTSEVMKLIISRELLSK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=48.0106100795756, Blast_Score=355, Evalue=4e-98,
Organism=Homo sapiens, GI226958412, Length=371, Percent_Identity=35.5795148247978, Blast_Score=234, Evalue=1e-61,
Organism=Homo sapiens, GI226958414, Length=342, Percent_Identity=37.1345029239766, Blast_Score=229, Evalue=3e-60,
Organism=Homo sapiens, GI4501859, Length=374, Percent_Identity=32.620320855615, Blast_Score=204, Evalue=9e-53,
Organism=Homo sapiens, GI4557233, Length=372, Percent_Identity=33.0645161290323, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI21361497, Length=388, Percent_Identity=32.7319587628866, Blast_Score=192, Evalue=3e-49,
Organism=Homo sapiens, GI187960098, Length=376, Percent_Identity=31.3829787234043, Blast_Score=184, Evalue=9e-47,
Organism=Homo sapiens, GI4557231, Length=376, Percent_Identity=31.3829787234043, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI76496475, Length=380, Percent_Identity=30.7894736842105, Blast_Score=178, Evalue=7e-45,
Organism=Homo sapiens, GI7656849, Length=365, Percent_Identity=30.958904109589, Blast_Score=178, Evalue=7e-45,
Organism=Homo sapiens, GI4557235, Length=380, Percent_Identity=30.7894736842105, Blast_Score=178, Evalue=7e-45,
Organism=Homo sapiens, GI4503943, Length=379, Percent_Identity=26.3852242744063, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI7669494, Length=353, Percent_Identity=26.628895184136, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI48976061, Length=334, Percent_Identity=26.6467065868263, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI211971008, Length=334, Percent_Identity=26.6467065868263, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI38505218, Length=293, Percent_Identity=25.938566552901, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI87081958, Length=390, Percent_Identity=30.5128205128205, Blast_Score=175, Evalue=6e-45,
Organism=Escherichia coli, GI1786223, Length=370, Percent_Identity=29.7297297297297, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI87081702, Length=384, Percent_Identity=25, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538396, Length=379, Percent_Identity=35.6200527704486, Blast_Score=226, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17533517, Length=371, Percent_Identity=33.4231805929919, Blast_Score=203, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17570075, Length=384, Percent_Identity=31.7708333333333, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI17551932, Length=370, Percent_Identity=32.4324324324324, Blast_Score=194, Evalue=5e-50,
Organism=Caenorhabditis elegans, GI17569725, Length=389, Percent_Identity=30.0771208226221, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17508101, Length=365, Percent_Identity=29.8630136986301, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17534899, Length=367, Percent_Identity=31.6076294277929, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17505929, Length=370, Percent_Identity=30.8108108108108, Blast_Score=184, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI17506239, Length=365, Percent_Identity=30.4109589041096, Blast_Score=177, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI71985184, Length=391, Percent_Identity=28.6445012787724, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71990804, Length=279, Percent_Identity=33.3333333333333, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI32563615, Length=230, Percent_Identity=33.9130434782609, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17534353, Length=377, Percent_Identity=27.8514588859416, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71985192, Length=290, Percent_Identity=29.6551724137931, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71982178, Length=271, Percent_Identity=25.830258302583, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17562446, Length=326, Percent_Identity=25.4601226993865, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21355753, Length=373, Percent_Identity=35.3887399463807, Blast_Score=211, Evalue=7e-55,
Organism=Drosophila melanogaster, GI21356377, Length=372, Percent_Identity=31.989247311828, Blast_Score=198, Evalue=4e-51,
Organism=Drosophila melanogaster, GI24660351, Length=386, Percent_Identity=31.8652849740933, Blast_Score=188, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24646207, Length=372, Percent_Identity=30.6451612903226, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24666513, Length=369, Percent_Identity=27.6422764227642, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI281363737, Length=347, Percent_Identity=31.1239193083574, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI19920834, Length=377, Percent_Identity=27.3209549071618, Blast_Score=106, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43207; Mature: 43207

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSISSSEQAELDLLRRSVETFCKQEVTPYYTNWEEQGMVPRQFWNKLGEQGFLLPEVP
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHCCCCCCCCCCC
EEYGGLGASFLYSTTIIESFCRQGYSSIAANLSVHDTILANYFLQYGTEEQKKYYLPRMI
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHCCHHH
SGELVGAIAMTEPGAGSDLQRIKTTANFDEGLNGYVLNGSKTFITNGQHCDFAIVVAKTK
CCHHEEEEEECCCCCCCHHHHHHHHCCCCCCCCCEEECCCEEEEECCCCCCEEEEEEEEE
VDVKPSKGISLFIVDAKKNGFTKGKNLEKIGLHACDTSELYFEDILLDESDILGGVNQGF
ECCCCCCCCEEEEEECCCCCCCCCCCCHHHCCEECCCCHHHHHHHHCCCHHHHCCCCHHH
SVLMNELPRERLIVANCAVASMEGVLTDTVSYVKERELFGTTLDQFQHTQFTLAELQTKV
HHHHHHCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVQRSFADECTTRCIEGNLDTATASMAKLSCTEVQGEVIDRCLQLFGGYGYMLEYPIARA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHH
YADARVQRIYGGTSEVMKLIISRELLSK
HHHHHHHHHHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLSISSSEQAELDLLRRSVETFCKQEVTPYYTNWEEQGMVPRQFWNKLGEQGFLLPEVP
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHCCCCCCCCCCC
EEYGGLGASFLYSTTIIESFCRQGYSSIAANLSVHDTILANYFLQYGTEEQKKYYLPRMI
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHCCHHH
SGELVGAIAMTEPGAGSDLQRIKTTANFDEGLNGYVLNGSKTFITNGQHCDFAIVVAKTK
CCHHEEEEEECCCCCCCHHHHHHHHCCCCCCCCCEEECCCEEEEECCCCCCEEEEEEEEE
VDVKPSKGISLFIVDAKKNGFTKGKNLEKIGLHACDTSELYFEDILLDESDILGGVNQGF
ECCCCCCCCEEEEEECCCCCCCCCCCCHHHCCEECCCCHHHHHHHHCCCHHHHCCCCHHH
SVLMNELPRERLIVANCAVASMEGVLTDTVSYVKERELFGTTLDQFQHTQFTLAELQTKV
HHHHHHCCHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVQRSFADECTTRCIEGNLDTATASMAKLSCTEVQGEVIDRCLQLFGGYGYMLEYPIARA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHH
YADARVQRIYGGTSEVMKLIISRELLSK
HHHHHHHHHHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]