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The map label for this gene is prkA [H]

Identifier: 23100109

GI number: 23100109

Start: 2720701

End: 2722596

Strand: Reverse

Name: prkA [H]

Synonym: OB2654

Alternate gene names: 23100109

Gene position: 2722596-2720701 (Counterclockwise)

Preceding gene: 23100110

Following gene: 28563943

Centisome position: 74.99

GC content: 34.44

Gene sequence:

>1896_bases
ATGGATATAATAAACAAAGTGAGAAATTTGAGAGATGAAGAAAAACGATTAGAATGGGAAGGTACATTCGCCGATTATTT
AGAAATAATAAAGGATCGTCCAGAAGTTGCTCAAACCGCACATTCACGTGTATATAATATGGTTAAAAGTGCAGGGGTAG
AGGAACGAGATGGTCGTAGAATGTATGAATTTTTTGGGTCATCCATTTTTGGCTTAGAGTCCGCAATCGAACGATTAGTA
GAAGAGTATTTTCATCCAGCTGCCAAACGACTCGATGTTAGAAAACGTATTTTGTTATTAATGGGGCCAGTTAGTGGAGG
GAAATCAACTATTGTTAGCATGTTGAAGAGAGGATTAGAACATTACTCTCGTACAGATGAAGGTGCAGTATATGCAATTA
AAGGTTGTCCGATGCATGAAGATCCTCTACATTTAATTCCACAACACTTAAGAGAAGATTTTTTCCAAGAATATGGTATT
CGTATTGAAGGTAGTTTATCGCCATTAAATACAATGAGATTGGATAAAGATTATGGTGGGAAAATTGAAGACGTAAAAGT
AGAACGGATCTTTTTCTCTGAAGATAAAAGAATAGGGATTGGAACATTTAGTCCATCAGATCCAAAATCACAAGATATTG
CTGATTTAACAGGAAGTATCGATTTTTCTACAATTGCAGAGTTCGGTTCCGAATCAGATCCGCGTGCCTATCGCTTTGAT
GGCGAGTTAAATAAAGCTAATCGTGGAATGATGGAATTTCAGGAAATCTTAAAAAGTGATGAGAAATTTTTATGGCATTT
ACTTTCTTTAACACAGGAAGGGAATTTTAAAGCTGGAAGGTTCGCTCTGATATCGGCAGACGAACTTATCATTGCGCATA
CAAACGAATCAGAGTATAAATCATTTATATCAAATAAGAAAAACGAAGCATTACATTCACGAATGATTGTTATGCCAATA
CCTTATAACTTGAAAGTAAGCGAAGAAGAGCGTATATATCAAAAAATGATTAAAGAAAGTGATATATCACATGTACATGT
GGCACCACATGCTTTACGAGCAGCAGCGATTTTTTCTATATTAAGTAGATTAAAAGAATCCAAAAAACAAGGCGTAGATG
TTGTTAAGAAAATGCGACTCTATGATGGGGAAAGCGTAGAAGGTTTTAATCAAGTAGATGTTGAAGAGCTGCGGAAAGAA
TATCAAGATGAAGGCATGGATGGAATAGATCCAAGATATGTCATTAATCGCATATCTTCTACGATTATTCGTAAAGAAAT
CCCATCAATTAATGCATTAGATGTTCTTCGTTCATTGAAAGAAGGTTTGGATCAACATCCATCTATTTCAAAAGATGATT
TGGAAACATATTTGAATTATATCTCGATTGCACGAAAAGAATATGATGAAATTGCAAAGAAAGAAGTACAAAAAGCTTTT
GTTTATTCATACGAGGAATCTGCAAAGACATTAATGGATAATTATCTTGATAATGTAGAGGCATACTGCAATAAGAATAA
GCTGCGTGATCCATTGACTGGAGAAGAAATGAATCCAGATGAAAAATTAATGCGCTCGATTGAAGAACAAATAGGTATTT
CAGAAAATGCGAAAAAAGCATTCCGAGAAGAAATTTTAATTCGATTATCTGCTTATGCAAGAAAAGGCAAACGTTTTGAC
TATAATTCGCATGAACGCTTAAGGGAAGCAATTCAGAAAAAGCTGTTTGCAGATTTAAAAGATGTGGTTAAAATCACTAC
CTCGTCCAAAACACCAGATGAATCACAACTTAAGAAGATTAATGAAGTTATTGCTCGTCTAATTGATGAACATGGTTATA
ATTCAGTTTCTGCAAATGAATTACTGCGGTATGTTGGAAGTTTATTGAATAGATAA

Upstream 100 bases:

>100_bases
TAGTTTATAAGGACCATTCGTCAAAATCATTCGTACAAGCATGATTTAAACAGCCTATGCATAGGATATAGAAATCGTTG
CAAGATGGAGGGAGTCATCG

Downstream 100 bases:

>100_bases
ATAGAAAAAGCCAAGAAGCTTGATTAGTGATCATCAACTTCTTGGCTTTTTTATTTGCAAATTGATCTAGTCCCAAGGTA
TAAATTATTCATTTGACATT

Product: serine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MDIINKVRNLRDEEKRLEWEGTFADYLEIIKDRPEVAQTAHSRVYNMVKSAGVEERDGRRMYEFFGSSIFGLESAIERLV
EEYFHPAAKRLDVRKRILLLMGPVSGGKSTIVSMLKRGLEHYSRTDEGAVYAIKGCPMHEDPLHLIPQHLREDFFQEYGI
RIEGSLSPLNTMRLDKDYGGKIEDVKVERIFFSEDKRIGIGTFSPSDPKSQDIADLTGSIDFSTIAEFGSESDPRAYRFD
GELNKANRGMMEFQEILKSDEKFLWHLLSLTQEGNFKAGRFALISADELIIAHTNESEYKSFISNKKNEALHSRMIVMPI
PYNLKVSEEERIYQKMIKESDISHVHVAPHALRAAAIFSILSRLKESKKQGVDVVKKMRLYDGESVEGFNQVDVEELRKE
YQDEGMDGIDPRYVINRISSTIIRKEIPSINALDVLRSLKEGLDQHPSISKDDLETYLNYISIARKEYDEIAKKEVQKAF
VYSYEESAKTLMDNYLDNVEAYCNKNKLRDPLTGEEMNPDEKLMRSIEEQIGISENAKKAFREEILIRLSAYARKGKRFD
YNSHERLREAIQKKLFADLKDVVKITTSSKTPDESQLKKINEVIARLIDEHGYNSVSANELLRYVGSLLNR

Sequences:

>Translated_631_residues
MDIINKVRNLRDEEKRLEWEGTFADYLEIIKDRPEVAQTAHSRVYNMVKSAGVEERDGRRMYEFFGSSIFGLESAIERLV
EEYFHPAAKRLDVRKRILLLMGPVSGGKSTIVSMLKRGLEHYSRTDEGAVYAIKGCPMHEDPLHLIPQHLREDFFQEYGI
RIEGSLSPLNTMRLDKDYGGKIEDVKVERIFFSEDKRIGIGTFSPSDPKSQDIADLTGSIDFSTIAEFGSESDPRAYRFD
GELNKANRGMMEFQEILKSDEKFLWHLLSLTQEGNFKAGRFALISADELIIAHTNESEYKSFISNKKNEALHSRMIVMPI
PYNLKVSEEERIYQKMIKESDISHVHVAPHALRAAAIFSILSRLKESKKQGVDVVKKMRLYDGESVEGFNQVDVEELRKE
YQDEGMDGIDPRYVINRISSTIIRKEIPSINALDVLRSLKEGLDQHPSISKDDLETYLNYISIARKEYDEIAKKEVQKAF
VYSYEESAKTLMDNYLDNVEAYCNKNKLRDPLTGEEMNPDEKLMRSIEEQIGISENAKKAFREEILIRLSAYARKGKRFD
YNSHERLREAIQKKLFADLKDVVKITTSSKTPDESQLKKINEVIARLIDEHGYNSVSANELLRYVGSLLNR
>Mature_631_residues
MDIINKVRNLRDEEKRLEWEGTFADYLEIIKDRPEVAQTAHSRVYNMVKSAGVEERDGRRMYEFFGSSIFGLESAIERLV
EEYFHPAAKRLDVRKRILLLMGPVSGGKSTIVSMLKRGLEHYSRTDEGAVYAIKGCPMHEDPLHLIPQHLREDFFQEYGI
RIEGSLSPLNTMRLDKDYGGKIEDVKVERIFFSEDKRIGIGTFSPSDPKSQDIADLTGSIDFSTIAEFGSESDPRAYRFD
GELNKANRGMMEFQEILKSDEKFLWHLLSLTQEGNFKAGRFALISADELIIAHTNESEYKSFISNKKNEALHSRMIVMPI
PYNLKVSEEERIYQKMIKESDISHVHVAPHALRAAAIFSILSRLKESKKQGVDVVKKMRLYDGESVEGFNQVDVEELRKE
YQDEGMDGIDPRYVINRISSTIIRKEIPSINALDVLRSLKEGLDQHPSISKDDLETYLNYISIARKEYDEIAKKEVQKAF
VYSYEESAKTLMDNYLDNVEAYCNKNKLRDPLTGEEMNPDEKLMRSIEEQIGISENAKKAFREEILIRLSAYARKGKRFD
YNSHERLREAIQKKLFADLKDVVKITTSSKTPDESQLKKINEVIARLIDEHGYNSVSANELLRYVGSLLNR

Specific function: Unknown

COG id: COG2766

COG function: function code T; Putative Ser protein kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prkA family [H]

Homologues:

Organism=Escherichia coli, GI1788083, Length=651, Percent_Identity=30.4147465437788, Blast_Score=266, Evalue=3e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013153
- InterPro:   IPR010650
- InterPro:   IPR016230 [H]

Pfam domain/function: PF08298 AAA_PrkA; PF06798 PrkA [H]

EC number: NA

Molecular weight: Translated: 72669; Mature: 72669

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00133 CARBOXYPEPT_ZN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIINKVRNLRDEEKRLEWEGTFADYLEIIKDRPEVAQTAHSRVYNMVKSAGVEERDGRR
CCHHHHHHCCCCHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHH
MYEFFGSSIFGLESAIERLVEEYFHPAAKRLDVRKRILLLMGPVSGGKSTIVSMLKRGLE
HHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
HYSRTDEGAVYAIKGCPMHEDPLHLIPQHLREDFFQEYGIRIEGSLSPLNTMRLDKDYGG
HHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHCCCCCCCC
KIEDVKVERIFFSEDKRIGIGTFSPSDPKSQDIADLTGSIDFSTIAEFGSESDPRAYRFD
CCCCEEEEEEEECCCCEEEECCCCCCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCEEEEC
GELNKANRGMMEFQEILKSDEKFLWHLLSLTQEGNFKAGRFALISADELIIAHTNESEYK
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCHHHHH
SFISNKKNEALHSRMIVMPIPYNLKVSEEERIYQKMIKESDISHVHVAPHALRAAAIFSI
HHHHCCHHHHHHHCEEEEECCCCCEECHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHH
LSRLKESKKQGVDVVKKMRLYDGESVEGFNQVDVEELRKEYQDEGMDGIDPRYVINRISS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
TIIRKEIPSINALDVLRSLKEGLDQHPSISKDDLETYLNYISIARKEYDEIAKKEVQKAF
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYSYEESAKTLMDNYLDNVEAYCNKNKLRDPLTGEEMNPDEKLMRSIEEQIGISENAKKA
HHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
FREEILIRLSAYARKGKRFDYNSHERLREAIQKKLFADLKDVVKITTSSKTPDESQLKKI
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
NEVIARLIDEHGYNSVSANELLRYVGSLLNR
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MDIINKVRNLRDEEKRLEWEGTFADYLEIIKDRPEVAQTAHSRVYNMVKSAGVEERDGRR
CCHHHHHHCCCCHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHH
MYEFFGSSIFGLESAIERLVEEYFHPAAKRLDVRKRILLLMGPVSGGKSTIVSMLKRGLE
HHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
HYSRTDEGAVYAIKGCPMHEDPLHLIPQHLREDFFQEYGIRIEGSLSPLNTMRLDKDYGG
HHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCHHHHCCCCCCCC
KIEDVKVERIFFSEDKRIGIGTFSPSDPKSQDIADLTGSIDFSTIAEFGSESDPRAYRFD
CCCCEEEEEEEECCCCEEEECCCCCCCCCCCHHHHHHCCCCHHHHHHHCCCCCCCEEEEC
GELNKANRGMMEFQEILKSDEKFLWHLLSLTQEGNFKAGRFALISADELIIAHTNESEYK
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCHHHHH
SFISNKKNEALHSRMIVMPIPYNLKVSEEERIYQKMIKESDISHVHVAPHALRAAAIFSI
HHHHCCHHHHHHHCEEEEECCCCCEECHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHH
LSRLKESKKQGVDVVKKMRLYDGESVEGFNQVDVEELRKEYQDEGMDGIDPRYVINRISS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
TIIRKEIPSINALDVLRSLKEGLDQHPSISKDDLETYLNYISIARKEYDEIAKKEVQKAF
HHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYSYEESAKTLMDNYLDNVEAYCNKNKLRDPLTGEEMNPDEKLMRSIEEQIGISENAKKA
HHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHH
FREEILIRLSAYARKGKRFDYNSHERLREAIQKKLFADLKDVVKITTSSKTPDESQLKKI
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
NEVIARLIDEHGYNSVSANELLRYVGSLLNR
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]